Natural products in drug discovery: advances and opportunities AG Atanasov, SB Zotchev, VM Dirsch, CT Supuran Nature reviews Drug discovery 20 (3), 200-216, 2021 | 3240 | 2021 |
G proteins control diverse pathways of transmembrane signaling1 M Freissmuth, PJ Casey, AG Gilman The FASEB journal 3 (10), 2125-2131, 1989 | 583 | 1989 |
Laryngeal recurrent nerve injury in surgery for benign thyroid diseases: effect of nerve dissection and impact of individual surgeon in more than 27,000 nerves at risk M Hermann, G Alk, R Roka, K Glaser, M Freissmuth Annals of surgery 235 (2), 261-268, 2002 | 521 | 2002 |
A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis K Kollmann, G Heller, C Schneckenleithner, W Warsch, R Scheicher, ... Cancer cell 24 (2), 167-181, 2013 | 370 | 2013 |
Neuromonitoring in thyroid surgery: prospective evaluation of intraoperative electrophysiological responses for the prediction of recurrent laryngeal nerve injury M Hermann, C Hellebart, M Freissmuth Annals of surgery 240 (1), 9-17, 2004 | 345 | 2004 |
Adenosine receptors: G protein-mediated signalling and the role of accessory proteins M Klinger, M Freissmuth, C Nanoff Cellular signalling 14 (2), 99-108, 2002 | 344 | 2002 |
Expression of Gsα in Escherichia coli: purification and properties of two forms of the protein MP Graziano, M Freissmuth, AG Gilman Journal of Biological Chemistry 264 (1), 409-418, 1989 | 306 | 1989 |
Amphetamines, new psychoactive drugs and the monoamine transporter cycle HH Sitte, M Freissmuth Trends in pharmacological sciences 36 (1), 41-50, 2015 | 288 | 2015 |
Risk factors for postoperative bleeding after thyroid surgery R Promberger, J Ott, F Kober, C Koppitsch, R Seemann, M Freissmuth, ... Journal of British Surgery 99 (3), 373-379, 2012 | 256 | 2012 |
Mutations of GS α designed to alter the reactivity of the protein with bacterial toxins: substitutions at ARG187 result in loss of GTPase activity M Freissmuth, AG Gilman Journal of Biological Chemistry 264 (36), 21907-21914, 1989 | 256 | 1989 |
Oligomerization of the human serotonin transporter and of the rat GABA transporter 1 visualized by fluorescence resonance energy transfer microscopy in living cells JA Schmid, P Scholze, O Kudlacek, M Freissmuth, EA Singer, HH Sitte Journal of Biological Chemistry 276 (6), 3805-3810, 2001 | 239 | 2001 |
Pharmakologie und Toxikologie M Freissmuth, S Offermanns, S Böhm Springer Berlin Heidelberg, 2016 | 237 | 2016 |
Stimulation of the mitogen-activated protein kinase via the A2A-adenosine receptor in primary human endothelial cells V Sexl, G Mancusi, C Höller, E Gloria-Maercker, W Schütz, M Freissmuth Journal of Biological Chemistry 272 (9), 5792-5799, 1997 | 225 | 1997 |
Reverse intrinsic activity of antagonists on G protein-coupled receptors W Schütz, M Freissmuth Trends in pharmacological sciences 13, 376-380, 1992 | 205 | 1992 |
Calmodulin dependence of presynaptic metabotropic glutamate receptor signaling V O'Connor, OE Far, E Bofill-Cardona, C Nanoff, M Freissmuth, ... Science 286 (5442), 1180-1184, 1999 | 196 | 1999 |
Suramin analogues as subtype-selective G protein inhibitors. M Freissmuth, S Boehm, W Beindl, P Nickel, AP Ijzerman, M Hohenegger, ... Molecular pharmacology 49 (4), 602-611, 1996 | 190 | 1996 |
STAT1 acts as a tumor promoter for leukemia development B Kovacic, D Stoiber, R Moriggl, E Weisz, RG Ott, R Kreibich, DE Levy, ... Cancer cell 10 (1), 77-87, 2006 | 176 | 2006 |
Functional expression of the human serotonin 5-HT1A receptor in Escherichia coli. Ligand binding properties and interaction with recombinant G protein alpha-subunits. B Bertin, M Freissmuth, RM Breyer, W Schütz, AD Strosberg, S Marullo Journal of Biological Chemistry 267 (12), 8200-8206, 1992 | 171 | 1992 |
Interactions of the bovine brain A1-adenosine receptor with recombinant G protein alpha-subunits. Selectivity for rGi alpha-3. M Freissmuth, W Schütz, ME Linder Journal of Biological Chemistry 266 (27), 17778-17783, 1991 | 170 | 1991 |
Physical interaction between the serotonin transporter and neuronal nitric oxide synthase underlies reciprocal modulation of their activity B Chanrion, C Mannoury la Cour, F Bertaso, M Lerner-Natoli, ... Proceedings of the National Academy of Sciences 104 (19), 8119-8124, 2007 | 169 | 2007 |