| Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease C Zuccato, A Ciammola, D Rigamonti, BR Leavitt, D Goffredo, L Conti, ... Science 293 (5529), 493-498, 2001 | 1599 | 2001 |
| Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease M Chen, VO Ona, M Li, RJ Ferrante, KB Fink, S Zhu, J Bian, L Guo, ... Nature medicine 6 (7), 797-801, 2000 | 1353 | 2000 |
| Neurotoxicity induces cleavage of p35 to p25 by calpain M Lee, YT Kwon, M Li, J Peng, RM Friedlander, LH Tsai Nature 405 (6784), 360-364, 2000 | 1315 | 2000 |
| Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice S Zhu, IG Stavrovskaya, M Drozda, BYS Kim, V Ona, M Li, S Sarang, ... Nature 417 (6884), 74-78, 2002 | 1299 | 2002 |
| Apoptosis and caspases in neurodegenerative diseases RM Friedlander New England Journal of Medicine 348 (14), 1365-1375, 2003 | 1218 | 2003 |
| Inhibition of interleukin 1β converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage H Hara, RM Friedlander, V Gagliardini, C Ayata, K Fink, Z Huang, ... Proceedings of the National Academy of Sciences 94 (5), 2007-2012, 1997 | 1144 | 1997 |
| Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease VO Ona, M Li, JPG Vonsattel, LJ Andrews, SQ Khan, WM Chung, AS Frey, ... Nature 399 (6733), 263-267, 1999 | 964 | 1999 |
| Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model M Li, VO Ona, C Guegan, M Chen, V Jackson-Lewis, LJ Andrews, ... Science 288 (5464), 335-339, 2000 | 866 | 2000 |
| Minocycline inhibits caspase-independent and-dependent mitochondrial cell death pathways in models of Huntington's disease X Wang, S Zhu, M Drozda, W Zhang, IG Stavrovskaya, E Cattaneo, ... Proceedings of the National Academy of Sciences 100 (18), 10483-10487, 2003 | 508 | 2003 |
| Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction ROS Mejia, VO Ona, M Li, RM Friedlander Neurosurgery 48 (6), 1393-1401, 2001 | 441 | 2001 |
| Arteriovenous malformations of the brain RM Friedlander New England Journal of Medicine 356 (26), 2704-2712, 2007 | 431 | 2007 |
| Expression of a dominant negative mutant of interleukin-1β converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic … RM Friedlander, V Gagliardini, H Hara, KB Fink, W Li, G MacDonald, ... The Journal of experimental medicine 185 (5), 933-940, 1997 | 425 | 1997 |
| Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury YD Teng, H Choi, RC Onario, S Zhu, FC Desilets, S Lan, EJ Woodard, ... Proceedings of the National Academy of Sciences 101 (9), 3071-3076, 2004 | 418 | 2004 |
| Inhibition of ICE slows ALS in mice RM Friedlander, RH Brown, V Gagliardini, J Wang, J Yuan Nature 388 (6637), 31-31, 1997 | 403 | 1997 |
| Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release Y Suofu, W Li, FG Jean-Alphonse, J Jia, NK Khattar, J Li, SV Baranov, ... Proceedings of the National Academy of Sciences 114 (38), E7997-E8006, 2017 | 399 | 2017 |
| Attenuation of transient focal cerebral ischemic injury in transgenic mice expressing a mutant ICE inhibitory protein H Hara, K Fink, M Endres, RM Friedlander, V Gagliardini, J Yuan, ... Journal of Cerebral Blood Flow & Metabolism 17 (4), 370-375, 1997 | 326 | 1997 |
| Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway. M Miura, RM Friedlander, J Yuan Proceedings of the National Academy of Sciences 92 (18), 8318-8322, 1995 | 324 | 1995 |
| Functional role and therapeutic implications of neuronal caspase-1 and-3 in a mouse model of traumatic spinal cord injury M Li, VO Ona, M Chen, M Kaul, L Tenneti, X Zhang, PE Stieg, SA Lipton, ... Neuroscience 99 (2), 333-342, 2000 | 288 | 2000 |
| Functional role of interleukin 1 beta (IL-1 beta) in IL-1 beta-converting enzyme-mediated apoptosis. RM Friedlander, V Gagliardini, RJ Rotello, J Yuan The Journal of experimental medicine 184 (2), 717-724, 1996 | 281 | 1996 |
| Cerebral intraparenchymal hemorrhage: a review BA Gross, BT Jankowitz, RM Friedlander Jama 321 (13), 1295-1303, 2019 | 265 | 2019 |
