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Seok-Man Ho
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Synergistic effects of common schizophrenia risk variants
N Schrode, SM Ho, K Yamamuro, A Dobbyn, L Huckins, MR Matos, ...
Nature genetics 51 (10), 1475-1485, 2019
2022019
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk
P Rajarajan, T Borrman, W Liao, N Schrode, E Flaherty, C Casiño, ...
Science 362 (6420), eaat4311, 2018
1962018
Dual Functions of Highly Potent Graphene Derivative–Poly-l-Lysine Composites To Inhibit Bacteria and Support Human Cells
S Some, SM Ho, P Dua, E Hwang, YH Shin, HJ Yoo, JS Kang, D Lee, ...
ACS nano 6 (8), 7151-7161, 2012
1612012
Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells
SM Ho, BJ Hartley, TCW Julia, M Beaumont, K Stafford, PA Slesinger, ...
Methods 101, 113-124, 2016
1552016
The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain
Y Jiang, YHE Loh, P Rajarajan, T Hirayama, W Liao, BS Kassim, ...
Nature genetics 49 (8), 1239-1250, 2017
1452017
Transformative network modeling of multi-omics data reveals detailed circuits, key regulators, and potential therapeutics for Alzheimer’s disease
M Wang, A Li, M Sekiya, ND Beckmann, X Quan, N Schrode, ...
Neuron 109 (2), 257-272. e14, 2021
1142021
In utero exposure to maternal smoking is associated with DNA methylation alterations and reduced neuronal content in the developing fetal brain
Z Chatterton, BJ Hartley, MH Seok, N Mendelev, S Chen, M Milekic, ...
Epigenetics & chromatin 10, 1-11, 2017
982017
Evaluating synthetic activation and repression of neuropsychiatric-related genes in hiPSC-derived NPCs, neurons, and astrocytes
SM Ho, BJ Hartley, E Flaherty, P Rajarajan, R Abdelaal, I Obiorah, ...
Stem cell reports 9 (2), 615-628, 2017
772017
Characterization of molecular and cellular phenotypes associated with a heterozygous CNTNAP2 deletion using patient-derived hiPSC neural cells
IS Lee, C Carvalho, P Douvaras, SM Ho, BJ Hartley, LW Zuccherato, ...
NPJ schizophrenia 1 (1), 1-5, 2015
602015
Cdo interacts with APPL1 and activates Akt in myoblast differentiation
GU Bae, JR Lee, BG Kim, JW Han, YE Leem, HJ Lee, SM Ho, MJ Hahn, ...
Molecular biology of the cell 21 (14), 2399-2411, 2010
582010
Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models
J Xu, BJ Hartley, P Kurup, A Phillips, A Topol, M Xu, C Ononenyi, ...
Molecular psychiatry 23 (2), 271-281, 2018
412018
TGF-β-activated kinase 1 (TAK1) and apoptosis signal-regulating kinase 1 (ASK1) interact with the promyogenic receptor Cdo to promote myogenic differentiation via activation of …
P Tran, SM Ho, BG Kim, TA Vuong, YE Leem, GU Bae, JS Kang
Journal of Biological Chemistry 287 (15), 11602-11615, 2012
412012
ASCL1-and DLX2-induced GABAergic neurons from hiPSC-derived NPCs
N Barretto, H Zhang, SK Powell, MB Fernando, S Zhang, EK Flaherty, ...
Journal of neuroscience methods 334, 108548, 2020
392020
Cdo suppresses canonical Wnt signalling via interaction with Lrp6 thereby promoting neuronal differentiation
MH Jeong, SM Ho, TA Vuong, SB Jo, G Liu, SA Aaronson, YE Leem, ...
Nature communications 5 (1), 5455, 2014
372014
Gas1 cooperates with Cdo and promotes myogenic differentiation via activation of p38MAPK
YE Leem, JW Han, HJ Lee, HL Ha, YL Kwon, SM Ho, BG Kim, P Tran, ...
Cellular signalling 23 (12), 2021-2029, 2011
352011
From “directed differentiation” to “neuronal induction”: Modeling neuropsychiatric disease: Supplementary issue: Stem cell biology
SM Ho, A Topol, KJ Brennand
Biomarker insights 10, BMI. S20066, 2015
342015
Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk
SK Powell, C O’Shea, K Townsley, I Prytkova, K Dobrindt, R Elahi, ...
Molecular psychiatry 28 (5), 1970-1982, 2023
152023
Integration of CRISPR-engineering and hiPSC-based models of psychiatric genomics
MR Matos, SM Ho, N Schrode, KJ Brennand
Molecular and Cellular Neuroscience 107, 103532, 2020
112020
Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons
A Li, S Cartwright, A Yu, SM Ho, N Schrode, PJM Deans, MR Matos, ...
STAR protocols 2 (2), 100580, 2021
52021
Activity-Dependent Transcriptional Program in NGN2+ Neurons Enriched for Genetic Risk for Brain-Related Disorders
Y Ma, J Bendl, BJ Hartley, JF Fullard, R Abdelaal, SM Ho, R Kosoy, ...
Biological Psychiatry 95 (2), 187-198, 2024
12024
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