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Dr Menuka Karki
Dr Menuka Karki
Harvard Medical School, Harvard University
Bestätigte E-Mail-Adresse bei hms.harvard.edu
Titel
Zitiert von
Zitiert von
Jahr
Comprehensive molecular characterization identifies distinct genomic and immune hallmarks of renal medullary carcinoma
P Msaouel, GG Malouf, X Su, H Yao, DN Tripathi, M Soeung, J Gao, ...
Cancer Cell 37 (5), 720-734. e13, 2020
882020
Exploring natural product chemistry and biology with multicomponent reactions. 5. Discovery of a novel tubulin-targeting scaffold derived from the rigidin family of marine …
LV Frolova, IV Magedov, AE Romero, M Karki, I Otero, K Hayden, ...
Journal of medicinal chemistry 56 (17), 6886-6900, 2013
612013
SETD2 Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma
YC Chiang, IY Park, EA Terzo, DN Tripathi, FM Mason, CC Fahey, M Karki, ...
Cancer research 78 (12), 3135-3146, 2018
562018
Precocious centriole disengagement and centrosome fragmentation induced by mitotic delay
M Karki, N Keyhaninejad, CB Shuster
Nature communications 8 (1), 15803, 2017
402017
The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase
RNH Seervai, RK Jangid, M Karki, DN Tripathi, SY Jung, SE Kearns, ...
Science advances 6 (40), eabb7854, 2020
332020
Synthetic and Biological Studies of Tubulin Targeting C2‐Substituted 7‐Deazahypoxanthines Derived from Marine Alkaloid Rigidins
R Scott, M Karki, MR Reisenauer, R Rodrigues, R Dasari, WR Smith, ...
ChemMedChem 9 (7), 1428-1435, 2014
332014
Somatic mutations in planar cell polarity genes in neural tissue from human fetuses with neural tube defects
T Tian, Y Lei, Y Chen, M Karki, L Jin, RH Finnell, L Wang, A Ren
Human genetics 139, 1299-1314, 2020
262020
A cytoskeletal function for PBRM1 reading methylated microtubules
M Karki, RK Jangid, R Anish, RNH Seervai, JP Bertocchio, T Hotta, ...
Science advances 7 (14), eabf2866, 2021
222021
Neuronal SETD2 activity links microtubule methylation to an anxiety-like phenotype in mice
M Koenning, X Wang, M Karki, RK Jangid, S Kearns, DN Tripathi, ...
Brain 144 (8), 2527-2540, 2021
132021
Reengineered epipodophyllotoxin
IV Magedov, NM Evdokimov, M Karki, AS Peretti, DT Lima, LV Frolova, ...
Chemical communications 48 (84), 10416-10418, 2012
112012
Bexarotene – a novel modulator of AURKA and the primary cilium in VHL-deficient cells
P Chowdhury, RT Powell, C Stephan, IP Uray, T Talley, M Karki, ...
Journal of cell science 131 (24), jcs219923, 2018
82018
FKBP8 variants are risk factors for spina bifida
T Tian, X Cao, SE Kim, YL Lin, JW Steele, RM Cabrera, M Karki, W Yang, ...
Human molecular genetics 29 (18), 3132-3144, 2020
42020
Neddylation inhibition sensitises renal medullary carcinoma tumours to platinum chemotherapy
DD Shapiro, NM Zacharias, DN Tripathi, M Karki, JP Bertocchio, ...
Clinical and Translational Medicine 13 (5), e1267, 2023
32023
CIC missense variants contribute to susceptibility for spina bifida
X Han, X Cao, V Aguiar‐Pulido, W Yang, M Karki, PAP Ramirez, ...
Human mutation 43 (12), 2021-2032, 2022
22022
SETD2 is an actin lysine methyltransferase
RNH Seervai, RK Jangid, M Karki, DN Tripathi, SY Jung, SE Kearns, ...
bioRxiv, 2020.04. 13.034629, 2020
12020
Direct detection of rpoB and katG gene mutations of Mycobacterium tuberculosis in clinical samples
S Pandey, A Lamichhane, A Byanjankar, A Kharel, C Rai, SP Lekhak, ...
Asian Pacific Journal of Tropical Biomedicine 7 (8), 698-701, 2017
12017
Hyperprogression due to myeloid mimicry in renal medullary carcinoma treated with nivolumab plus ipilimumab
M Soeung, X Yan, L Zhang, L Perelli, J Chen, BS Tidwell, H Khan, CN Le, ...
Cancer Research 84 (6_Supplement), 2702-2702, 2024
2024
A cytoskeletal function for PBRM1: reading methylated microtubules to maintain genomic stability
M Karki, R Jangid, R Anish, RN Seervai, JP Bertocchio, T Hotta, ...
Cancer Research 81 (13_Supplement), 2042-2042, 2021
2021
Regulation of Mitotic Centrosome Integrity and Cytokinesis in Cultured Human Cells
M Karki
New Mexico State University, 2017
2017
Prolonged prometaphase arrest induces centriole disengagement and centrosome fragmentation in cultured human cells.
M Karki, N Keyhaninejad, CB Shuster
MOLECULAR BIOLOGY OF THE CELL 26, 2015
2015
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