| Inflammatory cytokines provide a third signal for activation of naive CD4+ and CD8+ T cells JM Curtsinger, CS Schmidt, A Mondino, DC Lins, RM Kedl, MK Jenkins, ... The Journal of Immunology 162 (6), 3256-3262, 1999 | 932 | 1999 |
| Cutting edge: type I IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation JM Curtsinger, JO Valenzuela, P Agarwal, D Lins, MF Mescher The Journal of Immunology 174 (8), 4465-4469, 2005 | 852 | 2005 |
| Inflammatory cytokines as a third signal for T cell activation JM Curtsinger, MF Mescher Current opinion in immunology 22 (3), 333-340, 2010 | 815 | 2010 |
| Signals required for programming effector and memory development by CD8+ T cells MF Mescher, JM Curtsinger, P Agarwal, KA Casey, M Gerner, ... Immunological reviews 211 (1), 81-92, 2006 | 813 | 2006 |
| Signal 3 determines tolerance versus full activation of naive CD8 T cells: dissociating proliferation and development of effector function JM Curtsinger, DC Lins, MF Mescher The Journal of experimental medicine 197 (9), 1141-1151, 2003 | 763 | 2003 |
| CD8 T cell clonal expansion and development of effector function require prolonged exposure to antigen, costimulation, and signal 3 cytokine JM Curtsinger, CM Johnson, MF Mescher The Journal of Immunology 171 (10), 5165-5171, 2003 | 409 | 2003 |
| Purification and characterization of a prokaryotic glycoprotein from the cell envelope of Halobacterium salinarium. MF Mescher, JL Strominger Journal of Biological Chemistry 251 (7), 2005-2014, 1976 | 374 | 1976 |
| CTLA-4 Blockade Reverses CD8+ T Cell Tolerance to Tumor by a CD4+ T Cell–and IL-2-Dependent Mechanism P Shrikant, A Khoruts, MF Mescher Immunity 11 (4), 483-493, 1999 | 370 | 1999 |
| Programming for CD8 T cell memory development requires IL-12 or type I IFN Z Xiao, KA Casey, SC Jameson, JM Curtsinger, MF Mescher The Journal of Immunology 182 (5), 2786-2794, 2009 | 294 | 2009 |
| The roles of IL-12 in providing a third signal for clonal expansion of naive CD8 T cells J Valenzuela, C Schmidt, M Mescher The Journal of Immunology 169 (12), 6842-6849, 2002 | 281 | 2002 |
| Gene regulation and chromatin remodeling by IL-12 and type I IFN in programming for CD8 T cell effector function and memory P Agarwal, A Raghavan, SL Nandiwada, JM Curtsinger, PR Bohjanen, ... The Journal of Immunology 183 (3), 1695-1704, 2009 | 273 | 2009 |
| Cytotoxic T lymphocyte mediated lysis without release of serine esterase HL Ostergaard, KP Kane, MF Mescher, WR Clark Nature 330 (6143), 71-72, 1987 | 242 | 1987 |
| CD8+ memory T cells (CD44high, Ly-6C+) are more sensitive than naive cells (CD44low, Ly-6C−) to TCR/CD8 signaling in response to antigen JM Curtsinger, DC Lins, MF Mescher The Journal of Immunology 160 (7), 3236-3243, 1998 | 233 | 1998 |
| CD8+ T cells become nonresponsive (anergic) following activation in the presence of costimulation MJ Deeths, RM Kedl, MF Mescher The Journal of Immunology 163 (1), 102-110, 1999 | 222 | 1999 |
| Actin-containing matrix associated with the plasma membrane of murine tumour and lymphoid cells MF Mescher, MJL Jose, SP Balk Nature 289 (5794), 139-144, 1981 | 217 | 1981 |
| The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunity Y Wang, I Shaked, SM Stanford, W Zhou, JM Curtsinger, Z Mikulski, ... Immunity 39 (1), 111-122, 2013 | 205 | 2013 |
| Adjuvant effect of IL-12: conversion of peptide antigen administration from tolerizing to immunizing for CD8+ T cells in vivo CS Schmidt, MF Mescher The Journal of Immunology 163 (5), 2561-2567, 1999 | 197 | 1999 |
| Peptide antigen priming of naive, but not memory, CD8 T cells requires a third signal that can be provided by IL-12 CS Schmidt, MF Mescher The Journal of Immunology 168 (11), 5521-5529, 2002 | 180 | 2002 |
| Control of syngeneic tumor growth by activation of CD8+ T cells: efficacy is limited by migration away from the site and induction of nonresponsiveness P Shrikant, MF Mescher The Journal of Immunology 162 (5), 2858-2866, 1999 | 180 | 1999 |
| Activated CD8 binding to class I protein mediated by the T-cell receptor results in signalling AM O'Rourke, J Rogers, MF Mescher Nature 346 (6280), 187-189, 1990 | 179 | 1990 |
