Cooperative and independent roles of the Drp1 adaptors Mff, MiD49 and MiD51 in mitochondrial fission LD Osellame, AP Singh, DA Stroud, CS Palmer, D Stojanovski, ... Journal of cell science 129 (11), 2170-2181, 2016 | 321 | 2016 |
Structural insights into the membrane-anchoring mechanism of a cholesterol-dependent cytolysin R Ramachandran, AP Heuck, RK Tweten, AE Johnson Nature structural biology 9 (11), 823-827, 2002 | 243 | 2002 |
Dissecting dynamin's role in clathrin-mediated endocytosis M Mettlen, T Pucadyil, R Ramachandran, SL Schmid Biochemical Society Transactions 37 (5), 1022-1026, 2009 | 240 | 2009 |
Membrane-dependent conformational changes initiate cholesterol-dependent cytolysin oligomerization and intersubunit β-strand alignment R Ramachandran, RK Tweten, AE Johnson Nature structural & molecular biology 11 (8), 697-705, 2004 | 215 | 2004 |
The dynamin middle domain is critical for tetramerization and higher‐order self‐assembly R Ramachandran, M Surka, JS Chappie, DM Fowler, TR Foss, BD Song, ... The EMBO journal 26 (2), 559-566, 2007 | 208 | 2007 |
Crystal structures of the full-length murine and human gasdermin D reveal mechanisms of autoinhibition, lipid binding, and oligomerization Z Liu, C Wang, J Yang, B Zhou, R Yang, R Ramachandran, DW Abbott, ... Immunity 51 (1), 43-49. e4, 2019 | 176 | 2019 |
A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission PJ Macdonald, N Stepanyants, N Mehrotra, JA Mears, X Qi, H Sesaki, ... Molecular biology of the cell 25 (12), 1905-1915, 2014 | 172 | 2014 |
Coincident phosphatidic acid interaction restrains Drp1 in mitochondrial division Y Adachi, K Itoh, T Yamada, KL Cerveny, TL Suzuki, P Macdonald, ... Molecular cell 63 (6), 1034-1043, 2016 | 171 | 2016 |
Cardiolipin's propensity for phase transition and its reorganization by dynamin-related protein 1 form a basis for mitochondrial membrane fission N Stepanyants, PJ Macdonald, CA Francy, JA Mears, X Qi, ... Molecular biology of the cell 26 (17), 3104-3116, 2015 | 169 | 2015 |
Real‐time detection reveals that effectors couple dynamin's GTP‐dependent conformational changes to the membrane R Ramachandran, SL Schmid The EMBO journal 27 (1), 27-37, 2008 | 128 | 2008 |
Membrane insertion of the pleckstrin homology domain variable loop 1 is critical for dynamin-catalyzed vesicle scission R Ramachandran, TJ Pucadyil, YW Liu, S Acharya, M Leonard, ... Molecular biology of the cell 20 (22), 4630-4639, 2009 | 127 | 2009 |
The mechanoenzymatic core of dynamin-related protein 1 comprises the minimal machinery required for membrane constriction CA Francy, FJD Alvarez, L Zhou, R Ramachandran, JA Mears Journal of Biological Chemistry 290 (18), 11692-11703, 2015 | 123 | 2015 |
The dynamin superfamily R Ramachandran, S Schmid Current Biology 28 (8), R411-R416, 2018 | 119 | 2018 |
Robust colorimetric assays for dynamin's basal and stimulated GTPase activities M Leonard, BD Song, R Ramachandran, SL Schmid Methods in enzymology 404, 490-503, 2005 | 118 | 2005 |
Differential curvature sensing and generating activities of dynamin isoforms provide opportunities for tissue-specific regulation YW Liu, S Neumann, R Ramachandran, SM Ferguson, TJ Pucadyil, ... Proceedings of the National Academy of Sciences 108 (26), E234-E242, 2011 | 111 | 2011 |
The domains of a cholesterol-dependent cytolysin undergo a major FRET-detected rearrangement during pore formation R Ramachandran, RK Tweten, AE Johnson Proceedings of the National Academy of Sciences 102 (20), 7139-7144, 2005 | 109 | 2005 |
Distinct splice variants of dynamin-related protein 1 differentially utilize mitochondrial fission factor as an effector of cooperative GTPase activity PJ Macdonald, CA Francy, N Stepanyants, L Lehman, A Baglio, JA Mears, ... Journal of Biological Chemistry 291 (1), 493-507, 2016 | 95 | 2016 |
Dynamin-related protein 1 oligomerization in solution impairs functional interactions with membrane-anchored mitochondrial fission factor RW Clinton, CA Francy, R Ramachandran, X Qi, JA Mears Journal of Biological Chemistry 291 (1), 478-492, 2016 | 94 | 2016 |
Vesicle scission: dynamin R Ramachandran Seminars in cell & developmental biology 22 (1), 10-17, 2011 | 88 | 2011 |
Mitochondrial dynamics: The dynamin superfamily and execution by collusion R Ramachandran Seminars in cell & developmental biology 76, 201-212, 2018 | 76 | 2018 |