S. Christian Orrenius
S. Christian Orrenius
Head Computational Sciences, Nerviano Medical Sciences
Bestätigte E-Mail-Adresse bei - Startseite
Zitiert von
Zitiert von
Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death
P Magnaghi, R D'Alessio, B Valsasina, N Avanzi, S Rizzi, D Asa, ...
Nature Chemical Biology 9 (9), 548-556, 2013
Formation and reduction of glutathione-protein mixed disulfides during oxidative stress: A study with isolated hepatocytes and menadione (2-methyl-1, 4-naphthoquinone)
G Bellomo, F Mirabelli, D DiMonte, P Richelmi, H Thor, C Orrenius, ...
Biochemical pharmacology 36 (8), 1313-1320, 1987
Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs …
M Menichincheri, E Ardini, P Magnaghi, N Avanzi, P Banfi, R Bossi, ...
Journal of Medicinal Chemistry 59 (7), 3392-3408, 2016
Influence of molecular flexibility and polar surface area metrics on oral bioavailability in the rat
JJ Lu, K Crimin, JT Goodwin, P Crivori, C Orrenius, L Xing, PJ Tandler, ...
Journal of medicinal chemistry 47 (24), 6104-6107, 2004
Chiral recognition of alcohol enantiomers in acyl transfer reactions catalysed by Candida antarctica lipase B
C Orrenius, F Hbffner, D Rotticci, N öhrner, T Norin, K Hult
Biocatalysis and Biotransformation 16 (1), 1-15, 1998
Molecular recognition of sec-alcohol enantiomers by Candida antarctica lipase B
D Rotticci, F Hæffner, C Orrenius, T Norin, K Hult
Journal of Molecular Catalysis B: Enzymatic 5 (1), 267-272, 1998
Kinetic resolutions of amine and thiol analogues of secondary alcohols catalyzed by the Candida antarctica lipase B
N Öhrner, C Orrenius, A Mattson, T Norin, K Hult
Enzyme and microbial technology 19 (5), 328-331, 1996
The Candida antarctica lipase B catalysed kinetic resolution of seudenol in non-aqueous media of controlled water activity
C Orrenius, T Norin, K Hult, G Carrea
Tetrahedron: Asymmetry 6 (12), 3023-3030, 1995
Alkylsulfanyl-1, 2, 4-triazoles, a new class of allosteric valosine containing protein inhibitors. Synthesis and structure–activity relationships
P Polucci, P Magnaghi, M Angiolini, D Asa, N Avanzi, A Badari, J Bertrand, ...
Journal of medicinal chemistry 56 (2), 437-450, 2013
Preparation of a novel cross-linked polymer for second-order nonlinear optics
M Trollsås, C Orrenius, F Sahlen, UW Gedde, T Norin, A Hult, D Hermann, ...
Journal of the American Chemical Society 118 (36), 8542-8548, 1996
Candida antarctica lipase B catalysed kinetic resolutions: Substrate structure requirements for the preparation of enantiomerically enriched secondary alcanols
C Orrenius, N Öhrner, D Rotticci, A Mattson, K Hult, T Norin
Tetrahedron: Asymmetry 6 (5), 1217-1220, 1995
Afatinib Is a New Therapeutic Approach in Chordoma with a Unique Ability to Target EGFR and BrachyuryAfatinib Targets EGFR and Brachyury in Chordoma
P Magnaghi, B Salom, L Cozzi, N Amboldi, D Ballinari, E Tamborini, ...
Molecular cancer therapeutics 17 (3), 603-613, 2018
Enantiomerically enriched bifunctional sec-alcohols prepared by Candida antarctica lipase B catalysis. Evidence of non-steric interactions
D Rotticci, C Orrenius, K Hult, T Norin
Tetrahedron: Asymmetry 8 (3), 359-362, 1997
Model based on GRID-derived descriptors for estimating CYP3A4 enzyme stability of potential drug candidates
P Crivori, I Zamora, B Speed, C Orrenius, I Poggesi
Journal of computer-aided molecular design 18 (3), 155-166, 2004
Linear and nonlinear methods in modeling the aqueous solubility of organic compounds
C Catana, H Gao, C Orrenius, PFW Stouten
Journal of chemical information and modeling 45 (1), 170-176, 2005
Preparation of 1-pyridinylethanols of high enantiomeric purity by lipase catalysed transesterifications
C Orrenius, A Mattson, T Norin, N Öhrner, K Hult
Tetrahedron: Asymmetry 5 (7), 1363-1366, 1994
Discovery and optimization of pyrrolo [1, 2-a] pyrazinones leads to novel and selective inhibitors of PIM kinases
F Casuscelli, E Ardini, N Avanzi, E Casale, G Cervi, M D’Anello, D Donati, ...
Bioorganic & medicinal chemistry 21 (23), 7364-7380, 2013
Enthalpic and entropic contributions to lipase enantioselectivity
PL Overbeeke, SC Orrenius, JA Jongejan, JA Duine
Chemistry and physics of lipids 93 (1-2), 81-93, 1998
Lipase mediated resolution of γ-branched chain fatty acid methyl esters
N Heinsman, SC Orrenius, CLM Marcelis, A De Sousa Teixeira, ...
Biocatalysis and Biotransformation 16 (2), 145-162, 1998
Kinetic resolution of chiral auxiliaries with C2-symmetry by lipase-catalyzed alcoholysis and aminolysis
A Mattson, C Orrenius, N Ohrner, CR Unelius, K Hult, T Norin
Acta chemica scandinavica 50 (10), 918-921, 1996
Das System kann den Vorgang jetzt nicht ausführen. Versuchen Sie es später erneut.
Artikel 1–20