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Shreeram Akilesh
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FcRn: the neonatal Fc receptor comes of age
DC Roopenian, S Akilesh
Nature reviews immunology 7 (9), 715-725, 2007
26062007
Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6
K Ozaki, R Spolski, R Ettinger, HP Kim, G Wang, CF Qi, P Hwu, DJ Shaffer, ...
The Journal of Immunology 173 (9), 5361-5371, 2004
8282004
Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease
SB Petkova, S Akilesh, TJ Sproule, GJ Christianson, H Al Khabbaz, ...
International immunology 18 (12), 1759-1769, 2006
6472006
A catalog of genetic loci associated with kidney function from analyses of a million individuals
M Wuttke, Y Li, M Li, KB Sieber, MF Feitosa, M Gorski, A Tin, L Wang, ...
Nature genetics 51 (6), 957-972, 2019
6132019
The MHC class I-like IgG receptor controls perinatal IgG transport, IgG homeostasis, and fate of IgG-Fc-coupled drugs
DC Roopenian, GJ Christianson, TJ Sproule, AC Brown, S Akilesh, ...
The Journal of Immunology 170 (7), 3528-3533, 2003
5152003
Podocytes use FcRn to clear IgG from the glomerular basement membrane
S Akilesh, TB Huber, H Wu, G Wang, B Hartleben, JB Kopp, JH Miner, ...
Proceedings of the National Academy of Sciences 105 (3), 967-972, 2008
3052008
Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism
S Akilesh, GJ Christianson, DC Roopenian, AS Shaw
The Journal of Immunology 179 (7), 4580-4588, 2007
3012007
Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis
S Akilesh, H Suleiman, H Yu, MC Stander, P Lavin, R Gbadegesin, ...
The Journal of clinical investigation 121 (10), 4127-4137, 2011
2952011
The MHC class I–like Fc receptor promotes humorally mediated autoimmune disease
S Akilesh, S Petkova, TJ Sproule, DJ Shaffer, GJ Christianson, ...
The Journal of clinical investigation 113 (9), 1328-1333, 2004
2332004
Multicenter clinicopathologic correlation of kidney biopsies performed in COVID-19 patients presenting with acute kidney injury or proteinuria
S Akilesh, CC Nast, M Yamashita, K Henriksen, V Charu, ML Troxell, ...
American Journal of Kidney Diseases 77 (1), 82-93. e1, 2021
2052021
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria
A Teumer, Y Li, S Ghasemi, BP Prins, M Wuttke, T Hermle, A Giri, ...
Nature communications 10 (1), 4130, 2019
1492019
Rac1 activation in podocytes induces rapid foot process effacement and proteinuria
H Yu, H Suleiman, AHJ Kim, JH Miner, A Dani, AS Shaw, S Akilesh
Molecular and cellular biology 33 (23), 4755-4764, 2013
1442013
The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis
J Xie, L Liu, N Mladkova, Y Li, H Ren, W Wang, Z Cui, L Lin, X Hu, X Yu, ...
Nature communications 11 (1), 1600, 2020
1312020
Customized molecular phenotyping by quantitative gene expression and pattern recognition analysis
S Akilesh, DJ Shaffer, D Roopenian
Genome research 13 (7), 1719-1727, 2003
1202003
COVID-19 vasculopathy: mounting evidence for an indirect mechanism of endothelial injury
RF Nicosia, G Ligresti, N Caporarello, S Akilesh, D Ribatti
The American Journal of Pathology 191 (8), 1374-1384, 2021
922021
A 3D human renal cell carcinoma-on-a-chip for the study of tumor angiogenesis
CP Miller, C Tsuchida, Y Zheng, J Himmelfarb, S Akilesh
Neoplasia 20 (6), 610-620, 2018
892018
An ITAM-signaling pathway controls cross-presentation of particulate but not soluble antigens in dendritic cells
DB Graham, LM Stephenson, SK Lam, K Brim, HM Lee, J Bautista, ...
The Journal of experimental medicine 204 (12), 2889-2897, 2007
802007
B cell–derived IL-4 acts on podocytes to induce proteinuria and foot process effacement
AHJ Kim, JJ Chung, S Akilesh, A Koziell, S Jain, JB Hodgin, MJ Miller, ...
Jci Insight 2 (21), 2017
742017
Fibrillary glomerulonephritis: clinicopathologic features and atypical cases from a multi-institutional cohort
NK Andeen, ML Troxell, M Riazy, RS Avasare, J Lapasia, JA Jefferson, ...
Clinical Journal of the American Society of Nephrology 14 (12), 1741-1750, 2019
632019
Monoclonal antibodies directed against human FcRn and their applications
GJ Christianson, VZ Sun, S Akilesh, E Pesavento, G Proetzel, ...
MAbs 4 (2), 208-216, 2012
572012
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