| ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma MD Hogarty, MD Norris, K Davis, X Liu, NF Evageliou, CS Hayes, B Pawel, ... Cancer research 68 (23), 9735-9745, 2008 | 246 | 2008 |
| Increased frequency of spontaneous skin tumors in transgenic mice which overexpress ornithine decarboxylase L Megosh, SK Gilmour, D Rosson, AP Soler, M Blessing, JA Sawicki, ... Cancer research 55 (19), 4205-4209, 1995 | 184 | 1995 |
| Polyamine-blocking therapy reverses immunosuppression in the tumor microenvironment CS Hayes, AC Shicora, MP Keough, AE Snook, MR Burns, SK Gilmour Cancer immunology research 2 (3), 274-285, 2014 | 155 | 2014 |
| Role of ornithine decarboxylase in epidermal tumorigenesis A Clifford, D Morgan, SH Yuspa, AP Soler, S Gilmour Cancer research 55 (8), 1680-1686, 1995 | 153 | 1995 |
| Regulation of ornithine decarboxylase gene expression in mouse epidermis and epidermal tumors during two-stage tumorigenesis SK Gilmour, AK Verma, T Madara, TG O'Brien Cancer research 47 (5), 1221-1225, 1987 | 136 | 1987 |
| Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin. MK Smith, CS Trempus, SK Gilmour Carcinogenesis 19 (8), 1409-1415, 1998 | 107 | 1998 |
| High levels of intracellular polyamines promote histone acetyltransferase activity resulting in chromatin hyperacetylation CA Hobbs, SK Gilmour Journal of cellular biochemistry 77 (3), 345-360, 2000 | 103 | 2000 |
| Inhibition of ornithine decarboxylase (ODC) decreases tumor vascularization and reverses spontaneous tumors in ODC/Ras transgenic mice L Lan, C Trempus, SK Gilmour Cancer research 60 (20), 5696-5703, 2000 | 101 | 2000 |
| Polyamines and nonmelanoma skin cancer SK Gilmour Toxicology and applied pharmacology 224 (3), 249-256, 2007 | 98 | 2007 |
| Translational development of difluoromethylornithine (DFMO) for the treatment of neuroblastoma H Bassiri, A Benavides, M Haber, SK Gilmour, MD Norris, MD Hogarty Translational pediatrics 4 (3), 226, 2015 | 97 | 2015 |
| Use of dabigatran etexilate to reduce breast cancer progression K DeFeo, C Hayes, M Chernick, J Van Ryn, SK Gilmour Cancer biology & therapy 10 (10), 1001-1008, 2010 | 87 | 2010 |
| Induction of ornithine decarboxylase by 12-O-tetradecanoylphorbol 13-acetate in hamster fibroblasts. Relationship between levels of enzyme activity, immunoreactive protein, and … SK Gilmour, N Avdalovic, T Madara, TG O'Brien Journal of Biological Chemistry 260 (30), 16439-16444, 1985 | 82 | 1985 |
| A novel polyamine blockade therapy activates an anti-tumor immune response ET Alexander, A Minton, MC Peters, O Phanstiel IV, SK Gilmour Oncotarget 8 (48), 84140, 2017 | 78 | 2017 |
| Polyamine antagonist therapies inhibit neuroblastoma initiation and progression NF Evageliou, M Haber, A Vu, TW Laetsch, J Murray, LD Gamble, ... Clinical Cancer Research 22 (17), 4391-4404, 2016 | 76 | 2016 |
| Deregulation of polyamine biosynthesis alters intrinsic histone acetyltransferase and deacetylase activities in murine skin and tumors CA Hobbs, BA Paul, SK Gilmour Cancer research 62 (1), 67-74, 2002 | 74 | 2002 |
| K6/ODC transgenic mice as a sensitive model for carcinogen identification Y Chen, LC Megosh, SK Gilmour, JA Sawicki, TG O’Brien Toxicology letters 116 (1-2), 27-35, 2000 | 74 | 2000 |
| Ornithine decarboxylase expression leads to translocation and activation of protein kinase CK2 in vivo LJ Shore, AP Soler, SK Gilmour Journal of Biological Chemistry 272 (19), 12536-12543, 1997 | 65 | 1997 |
| Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion AJ Muller, JB DuHadaway, MY Chang, A Ramalingam, E Sutanto-Ward, ... Cancer immunology, immunotherapy 59, 1655-1663, 2010 | 64 | 2010 |
| Ornithine decarboxylase overexpression leads to increased epithelial tumor invasiveness MK Smith, MA Goral, JH Wright, LM Matrisian, RJ Morris, ... Cancer research 57 (11), 2104-2108, 1997 | 58 | 1997 |
| Ornithine decarboxylase over‐expression stimulates mitogen‐activated protein kinase and anchorage‐independent growth of human breast epithelial cells A Manni, R Wechter, S Gilmour, MF Verderame, D Mauger, LM Demers International journal of cancer 70 (2), 175-182, 1997 | 56 | 1997 |
