| A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration P Koch, T Opitz, JA Steinbeck, J Ladewig, O Brüstle Proceedings of the National Academy of Sciences 106 (9), 3225-3230, 2009 | 609 | 2009 |
| Small molecules enable highly efficient neuronal conversion of human fibroblasts J Ladewig, J Mertens, J Kesavan, J Doerr, D Poppe, F Glaue, S Herms, ... Nature methods 9 (6), 575-578, 2012 | 388 | 2012 |
| Excitation-induced ataxin-3 aggregation in neurons from patients with Machado–Joseph disease P Koch, P Breuer, M Peitz, J Jungverdorben, J Kesavan, D Poppe, J Doerr, ... Nature 480 (7378), 543-546, 2011 | 373 | 2011 |
| Human-induced pluripotent stem cells form functional neurons and improve recovery after grafting in stroke-damaged brain K Oki, J Tatarishvili, J Wood, P Koch, S Wattananit, Y Mine, E Monni, ... Stem cells 30 (6), 1120-1133, 2012 | 358 | 2012 |
| Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons A Falk, P Koch, J Kesavan, Y Takashima, J Ladewig, M Alexander, ... PloS one 7 (1), e29597, 2012 | 354 | 2012 |
| Leveling Waddington: the emergence of direct programming and the loss of cell fate hierarchies J Ladewig, P Koch, O Brüstle Nature reviews Molecular cell biology 14 (4), 225-236, 2013 | 303 | 2013 |
| An organoid-based model of cortical development identifies non-cell-autonomous defects in Wnt signaling contributing to Miller-Dieker syndrome V Iefremova, G Manikakis, O Krefft, A Jabali, K Weynans, R Wilkens, ... Cell reports 19 (1), 50-59, 2017 | 267 | 2017 |
| Analysis of short tandem repeat expansions and their methylation state with nanopore sequencing P Giesselmann, B Brändl, E Raimondeau, R Bowen, C Rohrandt, ... Nature biotechnology 37 (12), 1478-1481, 2019 | 165 | 2019 |
| Presenilin-1 L166P mutant human pluripotent stem cell–derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation P Koch, IY Tamboli, J Mertens, P Wunderlich, J Ladewig, K Stüber, ... The American journal of pathology 180 (6), 2404-2416, 2012 | 136 | 2012 |
| Genes and mechanisms involved in the generation and amplification of basal radial glial cells M Penisson, J Ladewig, R Belvindrah, F Francis Frontiers in cellular neuroscience 13, 381, 2019 | 93 | 2019 |
| APP processing in human pluripotent stem cell-derived neurons is resistant to NSAID-based γ-secretase modulation J Mertens, K Stüber, P Wunderlich, J Ladewig, JC Kesavan, ... Stem Cell Reports 1 (6), 491-498, 2013 | 86 | 2013 |
| Arylsulfatase A overexpressing human iPSC-derived neural cells reduce CNS sulfatide storage in a mouse model of metachromatic leukodystrophy J Doerr, A Böckenhoff, B Ewald, J Ladewig, M Eckhardt, V Gieselmann, ... Molecular Therapy 23 (9), 1519-1531, 2015 | 61 | 2015 |
| Widespread occurrence of serpin genes with multiple reactive centre-containing exon cassettes in insects and nematodes O Krüger, J Ladewig, K Köster, H Ragg Gene 293 (1-2), 97-105, 2002 | 59 | 2002 |
| Generation of standardized and reproducible forebrain-type cerebral organoids from human induced pluripotent stem cells O Krefft, A Jabali, V Iefremova, P Koch, J Ladewig Journal of Visualized Experiments: JoVE, 56768, 2018 | 54 | 2018 |
| Lineage selection of functional and cryopreservable human embryonic stem cell-derived neurons J Ladewig, P Koch, E Endl, B Meiners, T Opitz, S Couillard-Despres, ... Stem cells 26 (7), 1705-1712, 2008 | 53 | 2008 |
| Auto-attraction of neural precursors and their neuronal progeny impairs neuronal migration J Ladewig, P Koch, O Brüstle Nature neuroscience 17 (1), 24-26, 2014 | 48 | 2014 |
| Embryonic stem cell–based modeling of tau pathology in human neurons J Mertens, K Stüber, D Poppe, J Doerr, J Ladewig, O Brüstle, P Koch The American journal of pathology 182 (5), 1769-1779, 2013 | 46 | 2013 |
| Mutations in the heterotopia gene Eml1/EML1 severely disrupt the formation of primary cilia A Uzquiano, C Cifuentes-Diaz, A Jabali, DM Romero, A Houllier, F Dingli, ... Cell Reports 28 (6), 1596-1611. e10, 2019 | 40 | 2019 |
| Human cerebral organoids reveal progenitor pathology in EML1‐linked cortical malformation A Jabali, A Hoffrichter, A Uzquiano, F Marsoner, R Wilkens, M Siekmann, ... EMBO reports 23 (5), e54027, 2022 | 26 | 2022 |
| Human‐specific ARHGAP11B ensures human‐like basal progenitor levels in hominid cerebral organoids J Fischer, E Fernández Ortuño, F Marsoner, A Artioli, J Peters, T Namba, ... EMBO reports 23 (11), e54728, 2022 | 25 | 2022 |
