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Ryan J. Duchatel
Ryan J. Duchatel
ChadTough Defeat DIPG Fellow, University of Newcastle
Bestätigte E-Mail-Adresse bei newcastle.edu.au - Startseite
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Zitiert von
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Can hemp help? Low-THC cannabis and non-THC cannabinoids for the treatment of cancer
F Afrin, M Chi, AL Eamens, RJ Duchatel, AM Douglas, J Schneider, ...
Cancers 12 (4), 1033, 2020
562020
Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies
IJ Findlay, GN De Iuliis, RJ Duchatel, ER Jackson, NA Vitanza, JE Cain, ...
Oncogene 41 (4), 461-475, 2022
532022
Signal transduction in diffuse intrinsic pontine glioma
RJ Duchatel, ER Jackson, F Alvaro, B Nixon, H Hondermarck, MD Dun
Proteomics 19 (21-22), 1800479, 2019
472019
Increased white matter neuron density in a rat model of maternal immune activation—implications for schizophrenia
RJ Duchatel, P Jobling, BA Graham, LR Harms, PT Michie, DM Hodgson, ...
Progress in Neuro-Psychopharmacology and Biological Psychiatry 65, 118-126, 2016
342016
Preclinical and clinical evaluation of German-sourced ONC201 for the treatment of H3K27M-mutant diffuse intrinsic pontine glioma
RJ Duchatel, A Mannan, AS Woldu, T Hawtrey, PA Hindley, AM Douglas, ...
Neuro-oncology advances 3 (1), vdab169, 2021
332021
Clinical efficacy of ONC201 in H3K27M-mutant diffuse midline gliomas is driven by disruption of integrated metabolic and epigenetic pathways
S Venneti, AR Kawakibi, S Ji, SM Waszak, SR Sweha, M Mota, M Pun, ...
Cancer discovery 13 (11), 2370-2393, 2023
282023
White matter neuron biology and neuropathology in schizophrenia
RJ Duchatel, C Shannon Weickert, PA Tooney
npj Schizophrenia 5 (1), 10, 2019
272019
ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma
ER Jackson, RJ Duchatel, DE Staudt, ML Persson, A Mannan, S Yadavilli, ...
Cancer research 83 (14), 2421-2437, 2023
202023
Shwachman–Bodian–Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia
MD Dun, A Mannan, CJ Rigby, S Butler, HD Toop, D Beck, P Connerty, ...
Leukemia 34 (12), 3393-3397, 2020
172020
Increased complement component 4 (C4) gene expression in the cingulate cortex of rats exposed to late gestation immune activation
RJ Duchatel, CL Meehan, LR Harms, PT Michie, MJ Bigland, DW Smith, ...
Schizophrenia research 199, 442-444, 2018
172018
Late gestation immune activation increases IBA1-positive immunoreactivity levels in the corpus callosum of adult rat offspring
RJ Duchatel, CL Meehan, LR Harms, PT Michie, MJ Bigland, DW Smith, ...
Psychiatry research 266, 175-185, 2018
142018
B-cell lymphoma 6 (BCL6): from master regulator of humoral immunity to oncogenic driver in pediatric cancers
T McLachlan, WC Matthews, ER Jackson, DE Staudt, AM Douglas, ...
Molecular Cancer Research 20 (12), 1711-1723, 2022
112022
Reduced cortical somatostatin gene expression in a rat model of maternal immune activation
RJ Duchatel, LR Harms, CL Meehan, PT Michie, MJ Bigland, DW Smith, ...
Psychiatry Research 282, 112621, 2019
82019
A review of the anti-tumor potential of current therapeutics targeting the mitochondrial protease ClpP in H3K27-altered, diffuse midline glioma
ER Jackson, ML Persson, CJ Fish, IJ Findlay, S Mueller, J Nazarian, ...
Neuro-oncology, Epub ahead of print, 2023
72023
Dipg-03. Targeting pi3k using the blood brain barrier penetrable inhibitor, gdc-0084, for the treatment of diffuse intrinsic pontine glioma (dipg)
R Duchatel, E Jackson, A Patabendige, J Cain, M Tsoli, M Monje, F Alvaro, ...
Neuro-oncology 21 (Supplement_2), ii68-ii68, 2019
62019
Blockade of ROS production inhibits oncogenic signaling in acute myeloid leukemia and amplifies response to precision therapies
ZP Germon, JR Sillar, A Mannan, RJ Duchatel, D Staudt, HC Murray, ...
Science Signaling 16 (778), eabp9586, 2023
52023
Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection
DE Staudt, HC Murray, DA Skerrett-Byrne, ND Smith, MFB Jamaluddin, ...
Clinical proteomics 19 (1), 48, 2022
32022
PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma
RJ Duchatel, ER Jackson, SG Parackal, D Kiltschewskij, IJ Findlay, ...
The Journal of Clinical Investigation 134 (6), 2024
22024
A road map for the treatment of pediatric diffuse midline glioma
C Koschmann, WN Al-Holou, MM Alonso, J Anastas, P Bandopadhayay, ...
Cancer cell 42 (1), 1-5, 2024
22024
DIPG-29. Phosphatidylinositol-4, 5-bisphosphate 3-kinase (PI3K) inhibition drives protein kinase c activation (PKC) in diffuse intrinsic pontine glioma (DIPG)
RJ Duchatel, A Mannan, ER Jackson, D Staudt, DA Skerrett-Byrne, ...
Neuro-oncology 22 (Supplement_3), iii292-iii293, 2020
22020
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