Bjoern Papke
Bjoern Papke
Lineberger Comprehensice Cancer Center
Verified email at unc.edu - Homepage
Title
Cited by
Cited by
Year
Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling
G Zimmermann, B Papke, S Ismail, N Vartak, A Chandra, M Hoffmann, ...
Nature 497 (7451), 638-642, 2013
5122013
Drugging RAS: Know the enemy
B Papke, CJ Der
Science 355 (6330), 1158-1163, 2017
1982017
KRas localizes to the plasma membrane by spatial cycles of solubilization, trapping and vesicular transport
M Schmick, N Vartak, B Papke, M Kovacevic, DC Truxius, L Rossmannek, ...
Cell 157 (2), 459-471, 2014
1862014
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
KL Bryant, CA Stalnecker, D Zeitouni, JE Klomp, S Peng, AP Tikunov, ...
Nature medicine 25 (4), 628-640, 2019
1662019
Identification of pyrazolopyridazinones as PDEδ inhibitors
B Papke, S Murarka, HA Vogel, P Martín-Gago, M Kovacevic, DC Truxius, ...
Nature communications 7 (1), 1-9, 2016
1032016
The autodepalmitoylating activity of APT maintains the spatial organization of palmitoylated membrane proteins
N Vartak, B Papke, HE Grecco, L Rossmannek, H Waldmann, C Hedberg, ...
Biophysical journal 106 (1), 93-105, 2014
602014
Precise measurement of protein interacting fractions with fluorescence lifetime imaging microscopy
KA Walther, B Papke, MB Sinn, K Michel, A Kinkhabwala
Molecular Biosystems 7 (2), 322-336, 2011
462011
Atypical KRASG12R mutant is impaired in PI3K signaling and macropinocytosis in pancreatic cancer
GA Hobbs, NM Baker, AM Miermont, RD Thurman, M Pierobon, TH Tran, ...
Cancer discovery 10 (1), 104-123, 2020
232020
Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
I Ozkan-Dagliyan, JN Diehl, SD George, A Schaefer, B Papke, ...
Cell reports 31 (11), 107764, 2020
62020
Author Correction: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer (Nature Medicine,(2019), 25, 4,(628-640), 10.1038/s41591-019-0368-8)
KL Bryant, CA Stalnecker, D Zeitouni, JE Klomp, S Peng, AP Tikunov, ...
Nature medicine 26 (6), 982, 2020
22020
The Spatial Organization of Ras Signaling
B Papke, M Schmick, N Vartak, PIH Bastiaens
Ras Superfamily Small G Proteins: Biology and Mechanisms 1, 173-188, 2014
12014
Silencing of oncogenic KRAS by mutant-selective small interfering RNA
B Papke, SH Azam, AY Feng, C Gutierrez-Ford, H Huggins, PS Pallan, ...
ACS Pharmacology & Translational Science, 2020
2020
Abstract B32: Silencing of oncogenic KRAS by a mutant-favoring short interfering RNA
B Papke, AED Van Swearingen, AY Feng, SH Azam, EB Harrison, R Yang, ...
Molecular Cancer Research 18 (5 Supplement), B32-B32, 2020
2020
Abstract LB-287: Combination therapies with CDK4/6 inhibitors to treat KRAS-mutant pancreatic cancer
CM Goodwin, S Javaid, AM Waters, B Papke, R Yang, M Pierobon, ...
Cancer Research 79 (13 Supplement), LB-287-LB-287, 2019
2019
MA27. 06 Therapeutic Silencing of Oncogenic KRAS With a Mutant-Specific Short Interfering RNA
C Pecot, A Van Swearingen, B Papke
Journal of Thoracic Oncology 13 (10), S456, 2018
2018
Pharmacological interference with the PDEδ-K-Ras interaction impairs oncogenic K-Ras signaling
B Papke
Private Universität Witten/Herdecke Witten, 2014
2014
Targeting P130Cas-and Microtubule-Dependent MYC Regulation Sensitizes Pancreatic Cancer to ERK MAPK Inhibition
AM Waters, TO Khatib, B Papke, C Goodwin, GA Hobbs, JN Diehl, ...
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