Han Yuan
Han Yuan
Calico Life Sciences; Cornell University
Bestätigte E-Mail-Adresse bei
Zitiert von
Zitiert von
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia
AG Kotini, CJ Chang, A Chow, H Yuan, TC Ho, T Wang, S Vora, ...
Cell stem cell 20 (3), 315-328. e7, 2017
Multitask learning improves prediction of cancer drug sensitivity
H Yuan, I Paskov, H Paskov, AJ González, CS Leslie
Scientific reports 6 (1), 31619, 2016
Drosophila Muller F Elements Maintain a Distinct Set of Genomic Properties Over 40 Million Years of Evolution
W Leung, CD Shaffer, LK Reed, ST Smith, W Barshop, W Dirkes, ...
G3: Genes, Genomes, Genetics 5 (5), 719-740, 2015
Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation
J Dalal, JH Roh, SE Maloney, A Akuffo, S Shah, H Yuan, B Wamsley, ...
Genes & development 27 (5), 565-578, 2013
Cluster M mycobacteriophages Bongo, PegLeg, and Rey with unusually large repertoires of tRNA isotypes
WH Pope, KR Anders, M Baird, CA Bowman, MM Boyle, GW Broussard, ...
Journal of virology 88 (5), 2461-2480, 2014
Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets
T Wang, AR Pine, AG Kotini, H Yuan, L Zamparo, DT Starczynowski, ...
Cell Stem Cell 28 (6), 1074-1089. e7, 2021
scBasset: sequence-based modeling of single-cell ATAC-seq using convolutional neural networks
H Yuan, DR Kelley
Nature Methods 19 (9), 1088-1096, 2022
Novel insights from a multiomics dissection of the Hayflick limit
M Chan, H Yuan, I Soifer, TM Maile, RY Wang, A Ireland, JJ O'Brien, ...
Elife 11, e70283, 2022
BindSpace decodes transcription factor binding signals by large-scale sequence embedding
H Yuan, M Kshirsagar, L Zamparo, Y Lu, CS Leslie
Nature methods 16 (9), 858-861, 2019
Acute myeloid leukemia iPSCs reveal a role for RUNX1 in the maintenance of human leukemia stem cells
J Wesely, AG Kotini, F Izzo, H Luo, H Yuan, J Sun, M Georgomanoli, ...
Cell reports 31 (9), 107688, 2020
The complete cell atlas of an aging multicellular organism
AE Roux, H Yuan, K Podshivalova, D Hendrickson, R Kerr, C Kenyon, ...
bioRxiv, 2022.06. 15.496201, 2022
Novel extragenic genomic safe harbors for precise therapeutic T cell engineering
A Odak, H Yuan, J Feucht, VA Cantu, J Mansilla-Soto, F Kogel, J Eyquem, ...
Blood Journal, blood. 2022018924, 2023
Individual cell types in C. elegans age differently and activate distinct cell-protective responses
AE Roux, H Yuan, K Podshivalova, D Hendrickson, R Kerr, C Kenyon, ...
Cell Reports 42 (8), 2023
Investigation of Maternal Genotype Effects in Autism by Genome‐Wide Association
H Yuan, JD Dougherty
Autism Research 7 (2), 245-253, 2014
BindVAE: Dirichlet variational autoencoders for de novo motif discovery from accessible chromatin
M Kshirsagar, H Yuan, JL Ferres, C Leslie
Genome Biology 23 (1), 174, 2022
Globin vector regulatory elements are active in early hematopoietic progenitor cells
A Cabriolu, A Odak, L Zamparo, H Yuan, CS Leslie, M Sadelain
Molecular Therapy 30 (6), 2199-2209, 2022
Targeted Integration of a CAR at a Novel Genomic Safe Harbor Directs Potent Therapeutic Outcomes
A Odak, H Yuan, J Feucht, J Mansilla-Soto, J Eyquem, C Leslie, ...
Blood 136, 28, 2020
Novel Genomic Safe Harbors for Effective CAR T Cell Engineering
A Odak, H Yuan, J Mansilla-Soto, J Eyquem, P Vedantam, C Leslie, ...
MOLECULAR THERAPY 27 (4), 433-433, 2019
Modeling Large-scale Data Sets in Computational Genomics with Joint Learning
H Yuan
Weill Medical College of Cornell University, 2019
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