Antiviral Activity of Vitis vinifera Leaf Extract against SARS-CoV-2 and HSV-1 C Zannella, R Giugliano, A Chianese, C Buonocore, GA Vitale, G Sanna, ... Viruses 13 (7), 1263, 2021 | 63 | 2021 |
DOT1L: a key target in normal chromatin remodelling and in mixed-lineage leukaemia treatment F Sarno, A Nebbioso, L Altucci Epigenetics 15 (5), 439-453, 2020 | 58 | 2020 |
Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies M Brindisi, J Senger, C Cavella, A Grillo, G Chemi, S Gemma, ... European Journal of Medicinal Chemistry 157, 127-138, 2018 | 46 | 2018 |
Identification and characterization of PKF118-310 as a KDM4A inhibitor G Franci, F Sarno, A Nebbioso, L Altucci Epigenetics 12 (3), 198-205, 2017 | 43 | 2017 |
Discovery of the first-in-class GSK-3β/HDAC dual inhibitor as disease-modifying agent to combat Alzheimer’s disease A De Simone, V La Pietra, N Betari, N Petragnani, M Conte, S Daniele, ... ACS Medicinal Chemistry Letters 10 (4), 469-474, 2019 | 41 | 2019 |
Clinical epigenetics settings for cancer and cardiovascular diseases: real-life applications of network medicine at the bedside F Sarno, G Benincasa, M List, AL Barabasi, J Baumbach, F Ciardiello, ... Clinical Epigenetics 13, 1-38, 2021 | 40 | 2021 |
Epigenetic modulator UVI5008 inhibits MRSA by interfering with bacterial gyrase G Franci, V Folliero, M Cammarota, C Zannella, F Sarno, C Schiraldi, ... Scientific Reports 8 (1), 1-12, 2018 | 33 | 2018 |
Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells C Zwergel, M Schnekenburger, F Sarno, C Battistelli, MC Manara, G Stazi, ... Clinical epigenetics 11, 1-18, 2019 | 31 | 2019 |
Harnessing the role of HDAC6 in idiopathic pulmonary fibrosis: design, synthesis, structural analysis, and biological evaluation of potent inhibitors G Campiani, C Cavella, JD Osko, M Brindisi, N Relitti, S Brogi, ... Journal of medicinal chemistry 64 (14), 9960-9988, 2021 | 30 | 2021 |
Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation N Relitti, AP Saraswati, G Chemi, M Brindisi, S Brogi, D Herp, ... European Journal of Medicinal Chemistry 212, 112998, 2021 | 30 | 2021 |
Spiroindoline-capped selective HDAC6 inhibitors: design, synthesis, structural analysis, and biological evaluation AP Saraswati, N Relitti, M Brindisi, JD Osko, G Chemi, S Federico, A Grillo, ... ACS Medicinal Chemistry Letters 11 (11), 2268-2276, 2020 | 30 | 2020 |
Caldera unrest driven by CO2-induced drying of the deep hydrothermal system R Moretti, C Troise, F Sarno, G De Natale Scientific reports 8 (1), 8309, 2018 | 29 | 2018 |
Two novel SIRT1 activators, SCIC2 and SCIC2. 1, enhance SIRT1-mediated effects in stress response and senescence L Scisciola, F Sarno, V Carafa, S Cosconati, S Di Maro, L Ciuffreda, ... Epigenetics 15 (6-7), 664-683, 2020 | 26 | 2020 |
A new family of Jumonji C domain-containing KDM inhibitors inspired by natural product purpurogallin JA Souto, F Sarno, A Nebbioso, C Papulino, R Álvarez, J Lombino, ... Frontiers in chemistry 8, 312, 2020 | 18 | 2020 |
Trifolium Repens Blocks Proliferation in Chronic Myelogenous Leukemia via the BCR-ABL/STAT5 Pathway F Sarno, G Pepe, P Termolino, V Carafa, C Massaro, F Merciai, ... Cells 9 (2), 379, 2020 | 16 | 2020 |
3-Chloro-N′-(2-hydroxybenzylidene) benzohydrazide: an LSD1-selective inhibitor and iron-chelating agent for anticancer therapy F Sarno, C Papulino, G Franci, JH Andersen, B Cautain, C Melardo, ... Frontiers in Pharmacology 9, 413437, 2018 | 16 | 2018 |
Synthesis and Biological Evaluation of Tripartin, a Putative KDM4 Natural Product Inhibitor, and 1‐Dichloromethylinden‐1‐ol Analogues L Guillade, F Sarno, H Tarhonskaya, A Nebbioso, S Alvarez, A Kawamura, ... ChemMedChem 13 (18), 1949-1956, 2018 | 15 | 2018 |
Designing dual transglutaminase 2/histone deacetylase inhibitors effective at halting neuronal death M Basso, HH Chen, D Tripathy, M Conte, KYP Apperley, A De Simone, ... ChemMedChem 13 (3), 227-230, 2018 | 14 | 2018 |
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability S Federico, T Khan, A Fontana, S Brogi, R Benedetti, F Sarno, G Carullo, ... European Journal of Medicinal Chemistry 238, 114409, 2022 | 13 | 2022 |
The role of ozone carried by liposomes in the therapy of infectious and skin-regenerating ocular surface A Cutarelli, G Carlini, F Sarno, A Nebbioso, F Garofalo, L Altucci, ... Journal of Biomedical Science and Engineering 12 (7), 347-353, 2019 | 12 | 2019 |