The Achilles’ Heel of “Ultrastable” hyperthermophile proteins: submillimolar concentrations of SDS stimulate rapid conformational change, aggregation, and amyloid formation in … JM Khan, P Sharma, K Arora, N Kishor, P Kaila, P Guptasarma Biochemistry 55 (28), 3920-3936, 2016 | 31 | 2016 |
The conserved XPF: ERCC1-like Zip2: Spo16 complex controls meiotic crossover formation through structure-specific DNA binding K Arora, KD Corbett Nucleic acids research 47 (5), 2365-2376, 2019 | 28 | 2019 |
Calcium binding to beta-2-microglobulin at physiological pH drives the occurrence of conformational changes which cause the protein to precipitate into amorphous forms that … S Kumar, P Sharma, K Arora, M Raje, P Guptasarma PLoS One 9 (4), e95725, 2014 | 24 | 2014 |
The DNA-binding protein HU is a molecular glue that attaches bacteria to extracellular DNA in biofilms B Thakur, K Arora, A Gupta, P Guptasarma Journal of Biological Chemistry 296, 2021 | 18 | 2021 |
Single cell-level detection and quantitation of leaky protein expression from any strongly regulated bacterial system K Arora, SS Mangale, P Guptasarma Analytical biochemistry 484, 180-182, 2015 | 11 | 2015 |
Introduction of a thermophile-sourced ion pair network in the fourth beta/alpha unit of a psychophile-derived triosephosphate isomerase from Methanococcoides burtonii … N Dhaunta, K Arora, SK Chandrayan, P Guptasarma Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (6), 1023-1033, 2013 | 10 | 2013 |
HU-AB simulacrum: Fusion of HU-B and HU-A into HU-BA, a functional analog of the Escherichia coli HU-AB heterodimer K Arora, B Thakur, A Gupta, P Guptasarma Biochemical and Biophysical Research Communications 560, 27-31, 2021 | 4 | 2021 |
N-terminal extensions appear to frustrate HU heterodimer formation by strengthening intersubunit contacts and blocking the formation of a heterotetrameric intermediate K Arora, B Thakur, A Mrigwani, P Guptasarma Biochemistry 60 (23), 1836-1852, 2021 | 3 | 2021 |
Structure of Zip2: Spo16, a conserved XPF: ERCC1-like complex critical for meiotic crossover formation K Arora, KD Corbett bioRxiv, 258194, 2018 | 1 | 2018 |
Folding, Stability and DNA Binding of E. Coli Hu and its Engineered Variants K Arora, P Guptasarma IISERM, 2016 | | 2016 |
New Insights into DNA Binding and Dimerization Dynamics of E. Coli Histone Like Protein HU. K Arora, P Guptasarma The FASEB Journal 29, 710.2, 2015 | | 2015 |