| The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights AE Coutinho, KE Chapman Molecular and cellular endocrinology 335 (1), 2-13, 2011 | 1858 | 2011 |
| 11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action K Chapman, M Holmes, J Seckl Physiological reviews 93 (3), 1139-1206, 2013 | 866 | 2013 |
| 11 beta-hydroxysteroid dehydrogenase is an exclusive 11 beta-reductase in primary cultures of rat hepatocytes: effect of physicochemical and hormonal manipulations PM Jamieson, KE Chapman, CR Edwards, JR Seckl Endocrinology 136 (11), 4754-4761, 1995 | 406 | 1995 |
| Human placental 11 beta-hydroxysteroid dehydrogenase: evidence for and partial purification of a distinct NAD-dependent isoform RW Brown, KE Chapman, CR Edwards, JR Seckl Endocrinology 132 (6), 2614-2621, 1993 | 358 | 1993 |
| Postnatal handling increases the expression of cAMP-inducible transcription factors in the rat hippocampus: the effects of thyroid hormones and serotonin MJ Meaney, J Diorio, D Francis, S Weaver, J Yau, K Chapman, JR Seckl Journal of Neuroscience 20 (10), 3926-3935, 2000 | 322 | 2000 |
| Glucocorticoids and 11beta-hydroxysteroid dehydrogenase in adipose tissue JR Seckl, NM Morton, KE Chapman, BR Walker Recent progress in hormone research 59, 359-394, 2004 | 318 | 2004 |
| 5′-heterogeneity of glucocorticoid receptor messenger RNA is tissue specific: differential regulation of variant transcripts by early-life events JA McCormick, V Lyons, MD Jacobson, J Noble, J Diorio, M Nyirenda, ... Molecular endocrinology 14 (4), 506-517, 2000 | 313 | 2000 |
| Mineralocorticoid and glucocorticoid receptor balance in control of HPA axis and behaviour AP Harris, MC Holmes, ER De Kloet, KE Chapman, JR Seckl Psychoneuroendocrinology 38 (5), 648-658, 2013 | 263 | 2013 |
| Mutations that alter the ability of the Escherichia coli cyclic AMP receptor protein to activate transcription A Bell, K Gaston, R Williams, K Chapman, A Kolb, H Buc, S Minchin, ... Nucleic acids research 18 (24), 7243-7250, 1990 | 235 | 1990 |
| Cloning and production of antisera to human placental 11 β-hydroxysteroid dehydrogenase type 2 RW BROWN, KE CHAPMAN, Y KOTELEVTSEV, JLW YAU, RS LINDSAY, ... Biochemical Journal 313 (3), 1007-1017, 1996 | 216 | 1996 |
| Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11β-hydroxysteroid dehydrogenase type 1 IJ Bujalska, N Draper, Z Michailidou, JW Tomlinson, PC White, ... Journal of molecular endocrinology 34 (3), 675-684, 2005 | 210 | 2005 |
| High titers of transmissible spongiform encephalopathy infectivity associated with extremely low levels of PrPSc in vivo RM Barron, SL Campbell, D King, A Bellon, KE Chapman, RA Williamson, ... Journal of Biological Chemistry 282 (49), 35878-35886, 2007 | 188 | 2007 |
| High titers of transmissible spongiform encephalopathy infectivity associated with extremely low levels of PrPSc in vivo RM Barron, SL Campbell, D King, A Bellon, KE Chapman, RA Williamson, ... Journal of Biological Chemistry 282 (49), 35878-35886, 2007 | 188 | 2007 |
| Local amplification of glucocorticoids by 11β-hydroxysteroid dehydrogenase type 1 promotes macrophage phagocytosis of apoptotic leukocytes JS Gilmour, AE Coutinho, JF Cailhier, TY Man, M Clay, G Thomas, ... The Journal of Immunology 176 (12), 7605-7611, 2006 | 187 | 2006 |
| Glucocorticoid receptor is required for foetal heart maturation EA Rog-Zielinska, A Thomson, CJ Kenyon, DG Brownstein, CM Moran, ... Human molecular genetics 22 (16), 3269-3282, 2013 | 171 | 2013 |
| C/EBP regulates hepatic transcription of 11β-hydroxysteroid dehydrogenase type 1: a novel mechanism for cross-talk between the C/EBP and glucocorticoid signaling pathways LJS Williams, V Lyons, I MacLeod, V Rajan, GJ Darlington, V Poli, ... Journal of Biological Chemistry 275 (39), 30232-30239, 2000 | 159 | 2000 |
| 11β-Hydroxysteroid dehydrogenase 1 in adipocytes: expression is differentiation-dependent and hormonally regulated A Napolitano, MW Voice, CRW Edwards, JR Seckl, KE Chapman The Journal of Steroid Biochemistry and Molecular Biology 64 (5-6), 251-260, 1998 | 157 | 1998 |
| Early environmental regulation of hippocampal glucocorticoid receptor gene expression: characterization of intracellular mediators and potential genomic target sites ICG Weaver, P La Plante, S Weaver, A Parent, S Sharma, J Diorio, ... Molecular and cellular endocrinology 185 (1-2), 205-218, 2001 | 150 | 2001 |
| Changing glucocorticoid action: 11β-hydroxysteroid dehydrogenase type 1 in acute and chronic inflammation KE Chapman, AE Coutinho, Z Zhang, T Kipari, JS Savill, JR Seckl The Journal of steroid biochemistry and molecular biology 137, 82-92, 2013 | 149 | 2013 |
| 'Liver-type'11β-hydroxysteroid dehydrogenase cDNA encodes reductase but not dehydrogenase activity in intact mammalian COS-7 cells SC Low, KE Chapman, CRW Edwards, JR Seckl Journal of Molecular Endocrinology 13 (2), 167-174, 1994 | 146 | 1994 |
seckl jonathanUniversity of EdinburghVerified email at ed.ac.uk
