Cardiac cell modelling: observations from the heart of the cardiac physiome project M Fink, SA Niederer, EM Cherry, FH Fenton, JT Koivumäki, G Seemann, ... Progress in biophysics and molecular biology 104 (1-3), 2-21, 2011 | 187 | 2011 |
Impact of sarcoplasmic reticulum calcium release on calcium dynamics and action potential morphology in human atrial myocytes: a computational study JT Koivumäki, T Korhonen, P Tavi PLoS computational biology 7 (1), e1001067, 2011 | 161 | 2011 |
Benchmarking electrophysiological models of human atrial myocytes M Wilhelms, H Hettmann, MM Maleckar, JT Koivumäki, O Dössel, ... Frontiers in physiology 3, 487, 2013 | 156 | 2013 |
Method and arrangement for entering data in an electronic apparatus and an electronic apparatus J Mäntyjärvi, J Koivumäki, A Kinnula US Patent 6,956,506, 2005 | 149 | 2005 |
Structural Immaturity of Human iPSC-Derived Cardiomyocytes: In Silico Investigation of Effects on Function and Disease Modeling JT Koivumäki, N Naumenko, T Tuomainen, J Takalo, M Oksanen, ... Frontiers in physiology 9, 80, 2018 | 134 | 2018 |
Ca2+–calmodulin‐dependent protein kinase II represses cardiac transcription of the L‐type calcium channel α1C‐subunit gene (Cacna1c) by DREAM translocation JJ Ronkainen, SL Hänninen, T Korhonen, JT Koivumäki, R Skoumal, ... The Journal of physiology 589 (11), 2669-2686, 2011 | 104 | 2011 |
Variable t-tubule organization and Ca2+ homeostasis across the atria M Frisk, JT Koivumäki, PA Norseng, MM Maleckar, OM Sejersted, ... American Journal of Physiology-Heart and Circulatory Physiology 307 (4 …, 2014 | 96 | 2014 |
Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy M Prondzynski, MD Lemoine, ATL Zech, A Horváth, V Di Mauro, ... EMBO Molecular Medicine 11 (12), e11115, 2019 | 89 | 2019 |
Calcium signalling in developing cardiomyocytes: implications for model systems and disease WE Louch, JT Koivumäki, P Tavi The Journal of physiology 593 (5), 1047-1063, 2015 | 89 | 2015 |
Human induced pluripotent stem cell–derived engineered heart tissue as a sensitive test system for QT prolongation and arrhythmic triggers MD Lemoine, T Krause, JT Koivumäki, M Prondzynski, ML Schulze, ... Circulation: Arrhythmia and Electrophysiology 11 (7), e006035, 2018 | 79 | 2018 |
In Silico Screening of the Key Cellular Remodeling Targets in Chronic Atrial Fibrillation JT Koivumäki, G Seemann, MM Maleckar, P Tavi PLoS computational biology 10 (5), e1003620, 2014 | 70 | 2014 |
Modelling sarcoplasmic reticulum calcium ATPase and its regulation in cardiac myocytes JT Koivumäki, J Takalo, T Korhonen, P Tavi, M Weckström Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2009 | 56 | 2009 |
Computational modeling of electrophysiology and pharmacotherapy of atrial fibrillation: recent advances and future challenges M Vagos, IGM van Herck, J Sundnes, HJ Arevalo, AG Edwards, ... Frontiers in physiology 9, 1221, 2018 | 47 | 2018 |
Refractoriness in human atria: Time and voltage dependence of sodium channel availability L Skibsbye, T Jespersen, T Christ, MM Maleckar, J van den Brink, P Tavi, ... Journal of molecular and cellular cardiology 101, 26-34, 2016 | 47 | 2016 |
Keystroke recognition for virtual keyboard J Mantyjarvi, J Koivumaki, P Vuori Proceedings. IEEE International Conference on Multimedia and Expo 2, 429-432, 2002 | 45 | 2002 |
Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant L Yuan, JT Koivumäki, B Liang, LG Lorentzen, C Tang, MN Andersen, ... American Journal of Physiology-Heart and Circulatory Physiology 306 (8 …, 2014 | 35 | 2014 |
Local Ca2+ releases enable rapid heart rates in developing cardiomyocytes T Korhonen, R Rapila, VP Ronkainen, P Tavi Biophysical Journal 98 (3), 548a, 2010 | 34 | 2010 |
Na+ current expression in human atrial myofibroblasts: identity and functional roles JT Koivumäki, RB Clark, D Belke, C Kondo, PWM Fedak, MMC Maleckar, ... Frontiers in physiology 5, 275, 2014 | 33 | 2014 |
Regulation of excitation-contraction coupling in mouse cardiac myocytes: integrative analysis with mathematical modelling JT Koivumäki, T Korhonen, J Takalo, M Weckström, P Tavi BMC physiology 9 (1), 1-20, 2009 | 28 | 2009 |
hiPSC-derived cardiomyocyte model of LQT2 syndrome derived from asymptomatic and symptomatic mutation carriers reproduces clinical differences in aggregates but not in single cells D Shah, C Prajapati, K Penttinen, RM Cherian, JT Koivumäki, ... Cells 9 (5), 1153, 2020 | 25 | 2020 |