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| The most infectious prion protein particles JR Silveira, GJ Raymond, AG Hughson, RE Race, VL Sim, SF Hayes, ... Nature 437 (7056), 257-261, 2005 | 1084 | 2005 |
| Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy BW Caughey, A Dong, KS Bhat, D Ernst, SF Hayes, WS Caughey Biochemistry 30 (31), 7672-7680, 1991 | 1063 | 1991 |
| The scrapie-associated form of PrP is made from a cell surface precursor that is both protease-and phospholipase-sensitive. B Caughey, GJ Raymond Journal of Biological Chemistry 266 (27), 18217-18223, 1991 | 842 | 1991 |
| Anchorless prion protein results in infectious amyloid disease without clinical scrapie B Chesebro, M Trifilo, R Race, K Meade-White, C Teng, R LaCasse, ... Science 308 (5727), 1435-1439, 2005 | 771 | 2005 |
| Non-genetic propagation of strain-specific properties of scrapie prion protein RA Bessen, DA Kocisko, GJ Raymond, S Nandan, PT Lansbury, ... Nature 375 (6533), 698-700, 1995 | 686 | 1995 |
| Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells B Caughey, GJ Raymond Journal of virology 67 (2), 643-650, 1993 | 524 | 1993 |
| N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease (s): implications regarding the site of conversion of PrP to the protease-resistant state B Caughey, GJ Raymond, D Ernst, RE Race Journal of virology 65 (12), 6597-6603, 1991 | 510 | 1991 |
| Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassays JM Wilham, CD Orrú, RA Bessen, R Atarashi, K Sano, B Race, ... PLoS pathogens 6 (12), e1001217, 2010 | 502 | 2010 |
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| Prion protein biosynthesis in scrapie-infected and uninfected neuroblastoma cells B Caughey, RE Race, D Ernst, MJ Buchmeier, B Chesebro Journal of virology 63 (1), 175-181, 1989 | 447 | 1989 |
| Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation K Doh-Ura, T Iwaki, B Caughey Journal of virology 74 (10), 4894-4897, 2000 | 408 | 2000 |
| Strain-dependent differences in β-sheet conformations of abnormal prion protein B Caughey, GJ Raymond, RA Bessen Journal of Biological Chemistry 273 (48), 32230-32235, 1998 | 406 | 1998 |
| Real time quaking‐induced conversion analysis of cerebrospinal fluid in sporadic Creutzfeldt–Jakob disease LI McGuire, AH Peden, CD Orrú, JM Wilham, NE Appleford, G Mallinson, ... Annals of neurology 72 (2), 278-285, 2012 | 397 | 2012 |
| Ultrasensitive detection of scrapie prion protein using seeded conversion of recombinant prion protein R Atarashi, RA Moore, VL Sim, AG Hughson, DW Dorward, HA Onwubiko, ... Nature methods 4 (8), 645-650, 2007 | 392 | 2007 |
| A test for Creutzfeldt–Jakob disease using nasal brushings CD Orrú, M Bongianni, G Tonoli, S Ferrari, AG Hughson, BR Groveman, ... New England Journal of Medicine 371 (6), 519-529, 2014 | 386 | 2014 |
| Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions B Caughey, GS Baron, B Chesebro, M Jeffrey Annual review of biochemistry 78, 177-204, 2009 | 373 | 2009 |
| Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking R Atarashi, JM Wilham, L Christensen, AG Hughson, RA Moore, ... Nature methods 5 (3), 211-212, 2008 | 369 | 2008 |
| Prions and their partners in crime B Caughey, GS Baron Nature 443 (7113), 803-810, 2006 | 358 | 2006 |
