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Barbara Mair
Barbara Mair
Verified email at utoronto.ca
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Year
CLP1 links tRNA metabolism to progressive motor-neuron loss
T Hanada, S Weitzer, B Mair, C Bernreuther, BJ Wainger, J Ichida, ...
Nature 495 (7442), 474-480, 2013
2602013
Global genetic networks and the genotype-to-phenotype relationship
M Costanzo, E Kuzmin, J van Leeuwen, B Mair, J Moffat, C Boone, ...
Cell 177 (1), 85-100, 2019
1942019
Essential gene profiles for human pluripotent stem cells identify uncharacterized genes and substrate dependencies
B Mair, J Tomic, SN Masud, P Tonge, A Weiss, M Usaj, AHY Tong, ...
Cell reports 27 (2), 599-615. e12, 2019
962019
Digital microfluidic isolation of single cells for-Omics
J Lamanna, EY Scott, HS Edwards, MD Chamberlain, MDM Dryden, ...
Nature communications 11 (1), 5632, 2020
932020
Exploiting epigenetic vulnerabilities for cancer therapeutics
B Mair, S Kubicek, SMB Nijman
Trends in pharmacological sciences 35 (3), 136-145, 2014
742014
A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo
C Kofink, N Trainor, B Mair, S Wöhrle, M Wurm, N Mischerikow, MJ Roy, ...
Nature Communications 13 (1), 5969, 2022
722022
High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting
B Mair, PM Aldridge, RS Atwal, D Philpott, M Zhang, SN Masud, M Labib, ...
Nature Biomedical Engineering 3 (10), 796-805, 2019
682019
Gain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug Sensitivity
B Mair, T Konopka, C Kerzendorfer, K Sleiman, S Salic, V Serra, ...
PLoS genetics 12 (9), e1006279, 2016
542016
Genetic interaction networks in cancer cells
B Mair, J Moffat, C Boone, BJ Andrews
Current opinion in genetics & development 54, 64-72, 2019
352019
Discovery of a highly selective cell‐active inhibitor of the histone lysine demethylases KDM2/7
PA Gerken, JR Wolstenhulme, A Tumber, SB Hatch, Y Zhang, S Müller, ...
Angewandte Chemie International Edition 56 (49), 15555-15559, 2017
352017
MEK inhibitors block growth of lung tumours with mutations in ataxia–telangiectasia mutated
M Smida, F Fece de La Cruz, C Kerzendorfer, IZ Uras, B Mair, A Mazouzi, ...
Nature communications 7 (1), 13701, 2016
342016
A cohesin traffic pattern genetically linked to gene regulation
AL Valton, SV Venev, B Mair, ES Khokhar, AHY Tong, M Usaj, K Chan, ...
Nature structural & molecular biology 29 (12), 1239-1251, 2022
332022
CRISPR screens are feasible in TP53 wild‐type cells
KR Brown, B Mair, M Soste, J Moffat
Molecular systems biology 15 (8), e8679, 2019
332019
Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes
A Köferle, A Schlattl, A Hörmann, V Thatikonda, A Popa, F Spreitzer, ...
Cell reports 39 (2), 2022
282022
Targeting a cell state common to triple‐negative breast cancers
MK Muellner, B Mair, Y Ibrahim, C Kerzendorfer, H Lechtermann, ...
Molecular Systems Biology 11 (2), 789, 2015
242015
Intron excision from precursor tRNA molecules in mammalian cells requires ATP hydrolysis and phosphorylation of tRNA-splicing endonuclease components
B Mair, J Popow, K Mechtler, S Weitzer, J Martinez
Biochemical Society Transactions 41 (4), 831-837, 2013
62013
High-throughput microfluidic cell sorting platform (MICS)
D Philpott, P Aldridge, B Mair, R Atwal, S Masud, M Zhang, AHY Tong, ...
32019
Interrogation of cancer gene dependencies reveals novel paralog interactions of autosome and sex chromosome encoded genes
A Köferle, A Schlattl, A Hörmann, F Spreitzer, A Popa, V Thatikonda, ...
bioRxiv, 2021.05. 21.445116, 2021
12021
Scalable, FACS-Free Genome-Wide Phenotypic Screening
B Mair, PM Aldridge, RS Atwal, SN Masud, M Zhang, D Philpott, ...
bioRxiv, 612887, 2019
12019
SOS1 inhibition enhances the efficacy of and delays resistance to G12C inhibitors in lung adenocarcinoma
BR Daley, NE Sealover, E Sheffels, JM Hughes, D Gerlach, MH Hofmann, ...
bioRxiv, 2023.12. 07.570642, 2023
2023
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