Junjie Hu
Junjie Hu
Professor of Cell Biology, Institute of Biophysics
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A class of dynamin-like GTPases involved in the generation of the tubular ER network
J Hu, Y Shibata, PP Zhu, C Voss, N Rismanchi, WA Prinz, TA Rapoport, ...
Cell 138 (3), 549-561, 2009
Mechanisms shaping the membranes of cellular organelles
Y Shibata, J Hu, MM Kozlov, TA Rapoport
Annual Review of Cell and Developmental 25, 329-354, 2009
Membrane proteins of the endoplasmic reticulum induce high-curvature tubules
J Hu, Y Shibata, C Voss, T Shemesh, Z Li, M Coughlin, MM Kozlov, ...
Science 319 (5867), 1247-1250, 2008
Visualizing intracellular organelle and cytoskeletal interactions at nanoscale resolution on millisecond timescales
Y Guo, D Li, S Zhang, Y Yang, JJ Liu, X Wang, C Liu, DE Milkie, ...
Cell 175 (5), 1430-1442. e17, 2018
The reticulon and DP1/Yop1p proteins form immobile oligomers in the tubular endoplasmic reticulum
Y Shibata, C Voss, JM Rist, J Hu, TA Rapoport, WA Prinz, GK Voeltz
Journal of Biological Chemistry 283 (27), 18892-18904, 2008
The Vici syndrome protein EPG5 is a Rab7 effector that determines the fusion specificity of autophagosomes with late endosomes/lysosomes
Z Wang, G Miao, X Xue, X Guo, C Yuan, Z Wang, G Zhang, Y Chen, ...
Molecular cell 63 (5), 781-795, 2016
Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes
X Bian, RW Klemm, TY Liu, M Zhang, S Sun, X Sui, X Liu, TA Rapoport, ...
Proceedings of the National Academy of Sciences 108 (10), 3976-3981, 2011
Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK
SJ Marciniak, L Garcia-Bonilla, J Hu, HP Harding, D Ron
The Journal of cell biology 172 (2), 201-209, 2006
Structures of human mitofusin 1 provide insight into mitochondrial tethering
Y Qi, L Yan, C Yu, X Guo, X Zhou, X Hu, X Huang, Z Rao, Z Lou, J Hu
Journal of Cell Biology 215 (5), 621-629, 2016
Weaving the web of ER tubules
J Hu, WA Prinz, TA Rapoport
Cell 147 (6), 1226-1231, 2011
Mitochondrial fusion: the machineries in and out
S Gao, J Hu
Trends in cell biology 31 (1), 62-74, 2021
Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor
J Hu, J Liu, R Ghirlando, AR Saltiel, SR Hubbard
Molecular cell 12 (6), 1379-1389, 2003
Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14
RS Depetris, J Hu, I Gimpelevich, LJ Holt, RJ Daly, SR Hubbard
Molecular cell 20 (2), 325-333, 2005
Mutations in Orai1 transmembrane segment 1 cause STIM1-independent activation of Orai1 channels at glycine 98 and channel closure at arginine 91
SL Zhang, AV Yeromin, J Hu, A Amcheslavsky, H Zheng, MD Cahalan
Proceedings of the National Academy of Sciences 108 (43), 17838-17843, 2011
Shaping the endoplasmic reticulum into a social network
H Zhang, J Hu
Trends in cell biology 26 (12), 934-943, 2016
The dynamin-like GTPase Sey1p mediates homotypic ER fusion in S. cerevisiae
K Anwar, RW Klemm, A Condon, KN Severin, M Zhang, R Ghirlando, J Hu, ...
Journal of Cell Biology 197 (2), 209-217, 2012
Differential roles of the C and N termini of Orai1 protein in interacting with stromal interaction molecule 1 (STIM1) for Ca2+ release-activated Ca2+ (CRAC) channel activation
H Zheng, MH Zhou, C Hu, E Kuo, X Peng, J Hu, L Kuo, SL Zhang
Journal of Biological Chemistry 288 (16), 11263-11272, 2013
Lipid interaction of the C terminus and association of the transmembrane segments facilitate atlastin-mediated homotypic endoplasmic reticulum fusion
TY Liu, X Bian, S Sun, X Hu, RW Klemm, WA Prinz, TA Rapoport, J Hu
Proceedings of the National Academy of Sciences 109 (32), E2146-E2154, 2012
Structural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of adapter proteins
J Hu, SR Hubbard
Journal of Biological Chemistry 280 (19), 18943-18949, 2005
Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset
YJ Li, YL Cao, JX Feng, Y Qi, S Meng, JF Yang, YT Zhong, S Kang, ...
Nature communications 10 (1), 4914, 2019
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