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Ophiomics - Precision Medicine
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Comparative genomics of trypanosomatid parasitic protozoa
NM El-Sayed, PJ Myler, G Blandin, M Berriman, J Crabtree, G Aggarwal, ...
Science 309 (5733), 404-409, 2005
9802005
Evolution of the Rab family of small GTP-binding proteins
JB Pereira-Leal, MC Seabra
Journal of molecular biology 313 (4), 889-901, 2001
9522001
The mammalian Rab family of small GTPases: definition of family and subfamily sequence motifs suggests a mechanism for functional specificity in the Ras superfamily
JB Pereira-Leal, MC Seabra
Journal of molecular biology 301 (4), 1077-1087, 2000
5592000
Detection of functional modules from protein interaction networks
JB Pereira‐Leal, AJ Enright, CA Ouzounis
Proteins: Structure, Function, and Bioinformatics 54 (1), 49-57, 2004
5182004
Evolution: Tracing the origins of centrioles, cilia, and flagella
Z Carvalho-Santos, J Azimzadeh, JB Pereira-Leal, M Bettencourt-Dias
The Journal of cell biology 194 (2), 165, 2011
4342011
3D complex: a structural classification of protein complexes
ED Levy, JB Pereira-Leal, C Chothia, SA Teichmann
PLoS computational biology 2 (11), e155, 2006
3772006
Stepwise evolution of the centriole-assembly pathway
Z Carvalho-Santos, P Machado, P Branco, F Tavares-Cadete, ...
Journal of cell science 123 (9), 1414-1426, 2010
2442010
Prenylation of Rab GTPases: molecular mechanisms and involvement in genetic disease
JB Pereira-Leal, AN Hume, MC Seabra
FEBS letters 498 (2-3), 197-200, 2001
2302001
The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway
G Mosedale, W Niedzwiedz, A Alpi, F Perrina, JB Pereira-Leal, ...
Nature structural & molecular biology 12 (9), 763-771, 2005
2252005
The relationship between domain duplication and recombination
C Vogel, SA Teichmann, J Pereira-Leal
Journal of molecular biology 346 (1), 355-365, 2005
2152005
Evolution of protein complexes by duplication of homomeric interactions
JB Pereira-Leal, ED Levy, C Kamp, SA Teichmann
Genome biology 8 (4), 1-12, 2007
2052007
Thousands of rab GTPases for the cell biologist
Y Diekmann, E Seixas, M Gouw, F Tavares-Cadete, MC Seabra, ...
PLoS computational biology 7 (10), e1002217, 2011
1992011
Genome evolution reveals biochemical networks and functional modules
C Von Mering, EM Zdobnov, S Tsoka, FD Ciccarelli, JB Pereira-Leal, ...
Proceedings of the National Academy of Sciences 100 (26), 15428-15433, 2003
1992003
The superfamily of heme–copper oxygen reductases: types and evolutionary considerations
FL Sousa, RJ Alves, MA Ribeiro, JB Pereira-Leal, M Teixeira, MM Pereira
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1817 (4), 629-637, 2012
1972012
The origins and evolution of functional modules: lessons from protein complexes
JB Pereira-Leal, ED Levy, SA Teichmann
Philosophical Transactions of the Royal Society B: Biological Sciences 361 …, 2006
1802006
Evolution of intracellular compartmentalization
Y Diekmann, JB Pereira-Leal
Biochemical journal 449 (2), 319-331, 2013
1722013
Classification schemes for protein structure and function
CA Ouzounis, RMR Coulson, AJ Enright, V Kunin, JB Pereira-Leal
Nature Reviews Genetics 4 (7), 508-519, 2003
1612003
Actin stress fiber organization promotes cell stiffening and proliferation of pre-invasive breast cancer cells
S Tavares, AF Vieira, AV Taubenberger, M Araújo, NP Martins, ...
Nature communications 8 (1), 15237, 2017
1592017
Mechanisms underlying the dual-mode regulation of microtubule dynamics by Kip3/kinesin-8
X Su, W Qiu, ML Gupta, JB Pereira-Leal, SL Reck-Peterson, D Pellman
Molecular cell 43 (5), 751-763, 2011
1442011
Evolution and dynamics of protein interactions and networks
ED Levy, JB Pereira-Leal
Current opinion in structural biology 18 (3), 349-357, 2008
1362008
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