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David Nelles
David Nelles
Unknown affiliation
Verified email at u1bio.com - Homepage
Title
Cited by
Cited by
Year
Programmable RNA tracking in live cells with CRISPR/Cas9
DA Nelles, MY Fang, MR O’Connell, JL Xu, SJ Markmiller, JA Doudna, ...
Cell 165 (2), 488-496, 2016
5762016
Elimination of toxic microsatellite repeat expansion RNA by RNA-targeting Cas9
R Batra, DA Nelles, E Pirie, SM Blue, RJ Marina, H Wang, IA Chaim, ...
Cell 170 (5), 899-912. e10, 2017
2812017
Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development
L Kurian, A Aguirre, I Sancho-Martinez, C Benner, T Hishida, TB Nguyen, ...
Circulation 131 (14), 1278-1290, 2015
2092015
Intracellular mRNA regulation with self-assembled locked nucleic acid polymer nanoparticles
AM Rush, DA Nelles, AP Blum, SA Barnhill, ET Tatro, GW Yeo, ...
Journal of the American Chemical Society 136 (21), 7615-7618, 2014
622014
Tracking and manipulating cellular rna via nuclear delivery of crispr/cas9
G Yeo, DA Nelles, M Fang, R Batra
US Patent App. 15/359,567, 2017
582017
Applications of Cas9 as an RNA‐programmed RNA‐binding protein
DA Nelles, MY Fang, S Aigner, GW Yeo
BioEssays 37 (7), 732-739, 2015
492015
The sustained expression of Cas9 targeting toxic RNAs reverses disease phenotypes in mouse models of myotonic dystrophy type 1
R Batra, DA Nelles, DM Roth, F Krach, CA Nutter, T Tadokoro, JD Thomas, ...
Nature biomedical engineering 5 (2), 157-168, 2021
402021
Self-transfecting micellar RNA: modulating nanoparticle cell interactions via high density display of small molecule ligands on micelle coronas
A Roloff, DA Nelles, MP Thompson, GW Yeo, NC Gianneschi
Bioconjugate chemistry 29 (1), 126-135, 2018
292018
Directed editing of cellular RNA via nuclear delivery of CRISPR/CAS9
E Yeo, K Brannan, R Marina, D Nelles
US Patent 11,453,891, 2022
212022
Peptide brush polymers for efficient delivery of a gene editing protein to stem cells
AP Blum, DA Nelles, FJ Hidalgo, MA Touve, DS Sim, AA Madrigal, ...
Angewandte Chemie 131 (44), 15793-15796, 2019
192019
Alternative splicing in stem cell self-renewal and diferentiation
DA Nelles, GW Yeo
Adv Exp Med Biol 695, 92-104, 2010
122010
Reversal of molecular pathology by RNA-targeting Cas9 in a myotonic dystrophy mouse model
R Batra, DA Nelles, F Krach, JD Thomas, L Snjader, SM Blue, S Aigner, ...
bioRxiv, 184408, 2017
42017
Tracking and manipulating cellular RNA via nuclear delivery of CRISPR/CAS9
E Yeo, DA Nelles, M Fang, R Batra
US Patent 11,667,903, 2023
22023
Compositions and methods for the modulation of adaptive immunity
DA Nelles, R Batra, G Yeo
22019
Rna-targeting knockdown and replacement compositions and methods for use
DA Nelles, R Batra
US Patent App. 16/926,205, 2021
12021
Rna editing via recruitment of spliceosome components
DA Nelles
US Patent App. 18/362,698, 2024
2024
Rna-targeting compositions and methods for treating cag repeat diseases
DA Nelles, R Batra, D Roth, D Zisoulis, TA Angeline
US Patent App. 18/039,813, 2024
2024
Tracking and Manipulating Cellular RNA via Nuclear Delivery of CRISPR/CAS9
E Yeo, DA Nelles, M Fang, R Batra
US Patent App. 18/306,673, 2023
2023
Trans-splicing system for tissue-specific replacement of rna sequences
DA Nelles
US Patent App. 18/189,896, 2023
2023
Methods for identifying a cell uptake mechanism
E Yeo, E Van Nostrand, N Gianneschi, DA Nelles, S Barnhill, A Rush
US Patent App. 17/936,216, 2023
2023
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