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Adrian Jun Chu
Adrian Jun Chu
Postdoctoral Fellow, Department of Microbiology, Faculty of Medicine, The Chinese University of Hong
Verified email at cuhk.edu.hk
Title
Cited by
Cited by
Year
Discovery of Antibacterials That Inhibit Bacterial RNA Polymerase Interactions with Sigma Factors
J Ye, AJ Chu, R Harper, ST Chan, TL Shek, Y Zhang, M Ip, M Sambir, ...
Journal of Medicinal Chemistry 63 (14), 7695-7720, 2020
212020
First-in-class inhibitors targeting the interaction between bacterial RNA polymerase and sigma initiation factor affect the viability and toxin release of Streptococcus pneumoniae
J Ye, AJ Chu, L Lin, X Yang, C Ma
Molecules 24 (16), 2902, 2019
162019
Benzyl and benzoyl benzoic acid inhibitors of bacterial RNA polymerase-sigma factor interaction
J Ye, AJ Chu, L Lin, ST Chan, R Harper, M Xiao, I Artsimovitch, Z Zuo, ...
European Journal of Medicinal Chemistry 208, 112671, 2020
142020
Nusbiarylins Inhibit Transcription and Target Virulence Factors in Bacterial Pathogen Staphylococcus aureus
AJ Chu, Y Qiu, R Harper, L Lin, C Ma, X Yang
International Journal of Molecular Sciences 21 (16), 5772, 2020
112020
Synthesis and antimicrobial activity of an SO2-releasing siderophore conjugate
CM Black, AJ Chu, GH Thomas, A Routledge, AK Duhme-Klair
Journal of Inorganic Biochemistry 234, 111875, 2022
42022
Multi-methodological approach for the Quality assessment of Senecionis scandentis Herba (Qianliguang) in the herbal market
HL Ngai, X Yang, AJ Chu, R Harper, ABJE Jacobsen, DTW Lau, HY Yu, ...
PloS one 17 (4), e0267143, 2022
42022
Synthesis and biological evaluation of nusbiarylin derivatives as bacterial rRNA synthesis inhibitor with potent antimicrobial activity against MRSA and VRSA
Y Qiu, AJ Chu, TF Tsang, Y Zheng, NM Lam, KSL Li, M Ip, X Yang, C Ma
Bioorganic Chemistry 124, 105863, 2022
32022
Sulfonamidyl derivatives of sigmacidin: Protein-protein interaction inhibitors targeting bacterial RNA polymerase and sigma factor interaction exhibiting antimicrobial activity …
J Ye, CH Kan, Y Zheng, TF Tsang, AJ Chu, KH Chan, X Yang, C Ma
Bioorganic Chemistry 143, 106983, 2024
12024
Characterising two genomic islands involved in metabolism in Neisseria meningitidis
AJ Chu
University of York, 2017
12017
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