Discovery of Antibacterials That Inhibit Bacterial RNA Polymerase Interactions with Sigma Factors J Ye, AJ Chu, R Harper, ST Chan, TL Shek, Y Zhang, M Ip, M Sambir, ... Journal of Medicinal Chemistry 63 (14), 7695-7720, 2020 | 21 | 2020 |
First-in-class inhibitors targeting the interaction between bacterial RNA polymerase and sigma initiation factor affect the viability and toxin release of Streptococcus pneumoniae J Ye, AJ Chu, L Lin, X Yang, C Ma Molecules 24 (16), 2902, 2019 | 16 | 2019 |
Benzyl and benzoyl benzoic acid inhibitors of bacterial RNA polymerase-sigma factor interaction J Ye, AJ Chu, L Lin, ST Chan, R Harper, M Xiao, I Artsimovitch, Z Zuo, ... European Journal of Medicinal Chemistry 208, 112671, 2020 | 14 | 2020 |
Nusbiarylins Inhibit Transcription and Target Virulence Factors in Bacterial Pathogen Staphylococcus aureus AJ Chu, Y Qiu, R Harper, L Lin, C Ma, X Yang International Journal of Molecular Sciences 21 (16), 5772, 2020 | 11 | 2020 |
Synthesis and antimicrobial activity of an SO2-releasing siderophore conjugate CM Black, AJ Chu, GH Thomas, A Routledge, AK Duhme-Klair Journal of Inorganic Biochemistry 234, 111875, 2022 | 4 | 2022 |
Multi-methodological approach for the Quality assessment of Senecionis scandentis Herba (Qianliguang) in the herbal market HL Ngai, X Yang, AJ Chu, R Harper, ABJE Jacobsen, DTW Lau, HY Yu, ... PloS one 17 (4), e0267143, 2022 | 4 | 2022 |
Synthesis and biological evaluation of nusbiarylin derivatives as bacterial rRNA synthesis inhibitor with potent antimicrobial activity against MRSA and VRSA Y Qiu, AJ Chu, TF Tsang, Y Zheng, NM Lam, KSL Li, M Ip, X Yang, C Ma Bioorganic Chemistry 124, 105863, 2022 | 3 | 2022 |
Sulfonamidyl derivatives of sigmacidin: Protein-protein interaction inhibitors targeting bacterial RNA polymerase and sigma factor interaction exhibiting antimicrobial activity … J Ye, CH Kan, Y Zheng, TF Tsang, AJ Chu, KH Chan, X Yang, C Ma Bioorganic Chemistry 143, 106983, 2024 | 1 | 2024 |
Characterising two genomic islands involved in metabolism in Neisseria meningitidis AJ Chu University of York, 2017 | 1 | 2017 |