Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down’s syndrome X Altafaj, M Dierssen, C Baamonde, E Martí, J Visa, J Guimerà, M Oset, ... Human molecular genetics 10 (18), 1915-1923, 2001 | 424 | 2001 |
MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function E Miñones-Moyano, S Porta, G Escaramís, R Rabionet, S Iraola, ... Human molecular genetics 20 (15), 3067-3078, 2011 | 419 | 2011 |
BDNF and full-length and truncated TrkB expression in Alzheimer disease. Implications in therapeutic strategies I Ferrer, C Marín, MJ Rey, T Ribalta, E Goutan, R Blanco, E Tolosa, ... Journal of neuropathology and experimental neurology 58 (7), 729-739, 1999 | 377 | 1999 |
Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice V Fotaki, M Dierssen, S Alcántara, S Martínez, E Martí, C Casas, J Visa, ... Molecular and cellular biology 22 (18), 6636-6647, 2002 | 309 | 2002 |
A myriad of miRNA variants in control and Huntington’s disease brain regions detected by massively parallel sequencing E Martí, L Pantano, M Bañez-Coronel, F Llorens, E Miñones-Moyano, ... Nucleic acids research 38 (20), 7219-7235, 2010 | 262 | 2010 |
Evidence for the biogenesis of more than 1,000 novel human microRNAs MR Friedländer, E Lizano, AJS Houben, D Bezdan, M Báñez-Coronel, ... Genome biology 15 (4), 1-17, 2014 | 243 | 2014 |
Brain-derived neurotrophic factor reduces cortical cell death by ischemia after middle cerebral artery occlusion in the rat I Ferrer, J Krupinski, E Goutan, E Marti, S Ambrosio, E Arenas Acta neuropathologica 101 (3), 229-238, 2001 | 221 | 2001 |
SeqBuster, a bioinformatic tool for the processing and analysis of small RNAs datasets, reveals ubiquitous miRNA modifications in human embryonic cells L Pantano, X Estivill, E Martí Nucleic acids research 38 (5), e34-e34, 2010 | 160 | 2010 |
BDNF up‐regulates TrkB protein and prevents the death of CA1 neurons following transient forebrain ischemia I Ferrer, J Ballabriga, E Martí, E Pérez, J Alberch, E Arenas Brain pathology 8 (2), 253-261, 1998 | 157 | 1998 |
A pathogenic mechanism in Huntington's disease involves small CAG-repeated RNAs with neurotoxic activity M Bañez-Coronel, S Porta, B Kagerbauer, E Mateu-Huertas, L Pantano, ... PLoS Genet 8 (2), e1002481, 2012 | 151 | 2012 |
Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models I Ferrer, M Barrachina, B Puig, MM De Lagrán, E Martí, J Avila, ... Neurobiology of disease 20 (2), 392-400, 2005 | 147 | 2005 |
Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system. X Martí E, Altafaj, M Dierssen, S de la Luna, V Fotaki, M Alvarez, ... Brain Research 964 (2), 250-63, 2003 | 135 | 2003 |
Expression of caspases and their substrates in the rat model of focal cerebral ischemia J Krupinski, E Lopez, E Marti, I Ferrer Neurobiology of disease 7 (4), 332-342, 2000 | 127 | 2000 |
RCAN1 (DSCR1) increases neuronal susceptibility to oxidative stress: a potential pathogenic process in neurodegeneration S Porta, SA Serra, M Huch, MA Valverde, F Llorens, X Estivill, ML Arbones, ... Human molecular genetics 16 (9), 1039-1050, 2007 | 103 | 2007 |
Three-dimensional structure and survival of newly formed blood vessels after focal cerebral ischemia J Krupinski, P Stroemer, M Slevin, E Marti, P Kumar, F Rubio Neuroreport 14 (8), 1171-1176, 2003 | 95 | 2003 |
Motor phenotypic alterations in TgDyrk1a transgenic mice implicate DYRK1A in Down syndrome motor dysfunction MM de Lagrán, X Altafaj, X Gallego, E Martı, X Estivill, I Sahun, C Fillat, ... Neurobiology of disease 15 (1), 132-142, 2004 | 86 | 2004 |
NF-kB immunoreactivity is observed in association with beta A4 diffuse plaques in patients with Alzheimer's disease. I Ferrer, E Marti, E Lopez, A Tortosa Neuropathology and applied neurobiology 24 (4), 271-277, 1998 | 86 | 1998 |
A highly expressed miR-101 isomiR is a functional silencing small RNA F Llorens, M Bañez-Coronel, L Pantano, JA del Río, I Ferrer, X Estivill, ... BMC genomics 14 (1), 1-14, 2013 | 81 | 2013 |
BDNF, and full lenght and truncated TrkB expression in the hippocampus of the rat following kainic acid excitotoxic damage E Goutan, E Martí, I Ferrer Brain Research Molecular Brain Research 59 (2), 154-164, 1999 | 81* | 1999 |
Overexpression of miR-128 specifically inhibits the truncated isoform of NTRK3 and upregulates BCL2 in SH-SY5Y neuroblastoma cells M Guidi, M Muiños-Gimeno, B Kagerbauer, E Martí, X Estivill, ... BMC molecular biology 11 (1), 1-17, 2010 | 80 | 2010 |