Bin Chen
Titel
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Zitiert von
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A survey of current trends in computational drug repositioning
J Li, S Zheng, B Chen, AJ Butte, SJ Swamidass, Z Lu
Briefings in bioinformatics 17 (1), 2-12, 2016
3352016
Chem2Bio2RDF: a semantic framework for linking and data mining chemogenomic and systems chemical biology data
B Chen, X Dong, D Jiao, H Wang, Q Zhu, Y Ding, D Wild
BMC bioinformatics 11 (1), 255, 2010
2362010
Gaining insight into off-target mediated effects of drug candidates with a comprehensive systems chemical biology analysis
J Scheiber, B Chen, M Milik, SCK Sukuru, A Bender, D Mikhailov, ...
Journal of chemical information and modeling 49 (2), 308-317, 2009
1722009
PubChem as a source of polypharmacology
B Chen, D Wild, R Guha
Journal of chemical information and modeling 49 (9), 2044-2055, 2009
1582009
Assessing Drug Target Association using Semantic Linked Data
B Chen, Y Ding, DJ Wild
PLoS Computational Biology 8 (7), e1002574, 2012
1562012
Leveraging big data to transform target selection and drug discovery
B Chen, AJ Butte
Clinical Pharmacology & Therapeutics 99 (3), 285-297, 2016
1342016
Leveraging big data to transform target selection and drug discovery
B Chen, AJ Butte
Clinical Pharmacology & Therapeutics 99 (3), 285-297, 2016
1342016
The ChEMBL database as linked open data
EL Willighagen, A Waagmeester, O Spjuth, P Ansell, AJ Williams, ...
Journal of cheminformatics 5 (1), 1-12, 2013
1102013
Reversal of cancer gene expression correlates with drug efficacy and reveals therapeutic targets
B Chen, L Ma, H Paik, M Sirota, W Wei, MS Chua, S So, AJ Butte
Nature communications 8 (1), 1-12, 2017
862017
Predicting drug target interactions using meta-path-based semantic network analysis
G Fu, Y Ding, A Seal, B Chen, Y Sun, E Bolton
BMC bioinformatics 17 (1), 1-10, 2016
832016
Comparison of random forest and Pipeline Pilot Naive Bayes in prospective QSAR predictions.
B Chen, RP Sheridan, V Hornak, JH Voigt
Journal of Chemical Information and Modeling, 2012
782012
Relating genes to function: identifying enriched transcription factors using the ENCODE ChIP-Seq significance tool
RK Auerbach, B Chen, AJ Butte
Bioinformatics 29 (15), 1922-1924, 2013
692013
Relating hepatocellular carcinoma tumor samples and cell lines using gene expression data in translational research
B Chen, M Sirota, H Fan-Minogue, D Hadley, AJ Butte
BMC medical genomics 8 (2), 1-10, 2015
592015
Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice
S Zhang, X Song, D Cao, Z Xu, B Fan, L Che, J Hu, B Chen, M Dong, ...
Journal of hepatology 67 (6), 1194-1203, 2017
532017
Characteristics of drug combination therapy in oncology by analyzing clinical trial data on ClinicalTrials. gov
M Wu, M Sirota, AJ Butte, BIN Chen
Pacific Symposium on Biocomputing Co-Chairs, 68-79, 2014
522014
Relating chemical structure to cellular response: an integrative analysis of gene expression, bioactivity, and structural data across 11,000 compounds
B Chen, P Greenside, H Paik, M Sirota, D Hadley, AJ Butte
CPT: pharmacometrics & systems pharmacology 4 (10), 576-584, 2015
472015
PubChem BioAssays as a data source for predictive models
B Chen, DJ Wild
Journal of Molecular Graphics and Modelling 28 (5), 420-426, 2010
452010
Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell …
B Chen, W Wei, L Ma, B Yang, RM Gill, MS Chua, AJ Butte, S So
Gastroenterology 152 (8), 2022-2036, 2017
432017
Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types
K Yu, B Chen, D Aran, J Charalel, C Yau, DM Wolf, LJ van‘t Veer, AJ Butte, ...
Nature Communications 10 (1), 1-11, 2019
392019
Network medicine in disease analysis and therapeutics
B Chen, AJ Butte
Clinical Pharmacology & Therapeutics 94 (6), 627-629, 2013
342013
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