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Michelle C. Ward
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Insights into hominid evolution from the gorilla genome sequence
A Scally, JY Dutheil, LDW Hillier, GE Jordan, I Goodhead, J Herrero, ...
Nature 483 (7388), 169-175, 2012
8102012
Gibbon genome and the fast karyotype evolution of small apes
L Carbone, R Alan Harris, S Gnerre, KR Veeramah, B Lorente-Galdos, ...
Nature 513 (7517), 195-201, 2014
3572014
Impact of regulatory variation across human iPSCs and differentiated cells
NE Banovich, YI Li, A Raj, MC Ward, P Greenside, D Calderon, PY Tung, ...
Genome research 28 (1), 122-131, 2018
1302018
A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics
I Gallego Romero, BJ Pavlovic, I Hernando-Herraez, X Zhou, MC Ward, ...
Elife 4, e07103, 2015
1282015
Co-binding by YY1 identifies the transcriptionally active, highly conserved set of CTCF-bound regions in primate genomes
PC Schwalie, MC Ward, CE Cain, AJ Faure, Y Gilad, DT Odom, P Flicek
Genome biology 14, 1-15, 2013
882013
Latent regulatory potential of human-specific repetitive elements
MC Ward, MD Wilson, NL Barbosa-Morais, D Schmidt, R Stark, Q Pan, ...
Molecular cell 49 (2), 262-272, 2013
772013
Association of human iPSC gene signatures and X chromosome dosage with two distinct cardiac differentiation trajectories
A D'Antonio-Chronowska, MKR Donovan, WWY Greenwald, JP Nguyen, ...
Stem cell reports 13 (5), 924-938, 2019
542019
Functional dynamic genetic effects on gene regulation are specific to particular cell types and environmental conditions
AS Findley, A Monziani, AL Richards, K Rhodes, MC Ward, CA Kalita, ...
eLife 10, e67077, 2021
482021
Dynamic effects of genetic variation on gene expression revealed following hypoxic stress in cardiomyocytes
MC Ward, NE Banovich, A Sarkar, M Stephens, Y Gilad
Elife 10, e57345, 2021
432021
A generally conserved response to hypoxia in iPSC-derived cardiomyocytes from humans and chimpanzees
MC Ward, Y Gilad
eLife 8, e42374, 2019
372019
Silencing of transposable elements may not be a major driver of regulatory evolution in primate iPSCs
MC Ward, S Zhao, K Luo, BJ Pavlovic, MM Karimi, M Stephens, Y Gilad
eLife 7, e33084, 2018
292018
Cracking the regulatory code
MC Ward, Y Gilad
Nature 550 (7675), 190-191, 2017
162017
Deregulated LAP2α expression in cervical cancer associates with aberrant E2F and p53 activities
MC Ward, PJ van der Watt, G Tzoneva, VD Leaner
IUBMB life 63 (11), 1018-1026, 2011
122011
Successful transmission and transcriptional deployment of a human chromosome via mouse male meiosis
C Ernst, J Pike, SJ Aitken, HK Long, N Eling, L Stojic, MC Ward, F Connor, ...
eLife 5, e20235, 2016
32016
Lamina-associated Polypeptide 2 (LAP2) Expression Patterns in Transformed and Cancer Cells
MC Ward
University of Cape Town, 2009
12009
Anthracyclines induce cardiotoxicity through a shared gene expression response signature
ER Matthews, OD Johnson, KJ Horn, JA Gutiérrez, SR Powell, MC Ward
PLoS genetics 20 (2), e1011164, 2024
2024
Anthracycline-induced cardiotoxicity associates with a shared gene expression response signature to TOP2-inhibiting breast cancer drugs in cardiomyocytes
ER Matthews, OD Johnson, KJ Horn, JA Gutiérrez, SR Powell, MC Ward
bioRxiv, 2023.10. 03.560405, 2023
2023
Abstract P3108: Induced-Pluripotent Stem Cell-Derived Cardiomyocytes As A Model To Investigate Cardiotoxicity Of A Panel Of Breast Cancer Drugs
ER Matthews, O Johnson, JA Gutierrez, M Ward
Circulation Research 131 (Suppl_1), AP3108-AP3108, 2022
2022
The regulatory potential of repetitive elements in mammalian genomes
MC Ward
University of Cambridge, 2013
2013
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