Mucoadhesion mechanism of chitosan and thiolated chitosan-poly (isobutyl cyanoacrylate) core-shell nanoparticles I Bravo-Osuna, C Vauthier, A Farabollini, GF Palmieri, G Ponchel Biomaterials 28 (13), 2233-2243, 2007 | 364 | 2007 |
The potential of using biodegradable microspheres in retinal diseases and other intraocular pathologies R Herrero-Vanrell, I Bravo-Osuna, V Andrés-Guerrero, ... Progress in retinal and eye research 42, 27-43, 2014 | 150 | 2014 |
Retinal ganglion cells survival in a glaucoma model by GDNF/Vit E PLGA microspheres prepared according to a novel microencapsulation procedure P Checa-Casalengua, C Jiang, I Bravo-Osuna, BA Tucker, ... Journal of controlled release 156 (1), 92-100, 2011 | 121 | 2011 |
Development and in vitro evaluation of a thiomer-based nanoparticulate gene delivery system T Schmitz, I Bravo-Osuna, C Vauthier, G Ponchel, B Loretz, ... Biomaterials 28 (3), 524-531, 2007 | 105 | 2007 |
Tuning of shell and core characteristics of chitosan-decorated acrylic nanoparticles I Bravo-Osuna, G Ponchel, C Vauthier European journal of pharmaceutical sciences 30 (2), 143-154, 2007 | 97 | 2007 |
Characterization of chitosan thiolation and application to thiol quantification onto nanoparticle surface I Bravo-Osuna, D Teutonico, S Arpicco, C Vauthier, G Ponchel International journal of pharmaceutics 340 (1-2), 173-181, 2007 | 96 | 2007 |
In vitro evaluation of calcium binding capacity of chitosan and thiolated chitosan poly (isobutyl cyanoacrylate) core–shell nanoparticles I Bravo-Osuna, G Millotti, C Vauthier, G Ponchel International journal of pharmaceutics 338 (1-2), 284-290, 2007 | 92 | 2007 |
Drug release kinetics and fronts movement studies from methyl methacrylate (MMA) copolymer matrix tablets: effect of copolymer type and matrix porosity C Ferrero, I Bravo, MR Jiménez-Castellanos Journal of controlled release 92 (1-2), 69-82, 2003 | 83 | 2003 |
Elaboration and characterization of thiolated chitosan-coated acrylic nanoparticles I Bravo-Osuna, T Schmitz, A Bernkop-Schnürch, C Vauthier, G Ponchel International journal of pharmaceutics 316 (1-2), 170-175, 2006 | 81 | 2006 |
Simultaneous co-delivery of neuroprotective drugs from multi-loaded PLGA microspheres for the treatment of glaucoma A Arranz-Romera, BM Davis, I Bravo-Osuna, S Esteban-Pérez, ... Journal of controlled release 297, 26-38, 2019 | 72 | 2019 |
Novel water-soluble mucoadhesive carbosilane dendrimers for ocular administration I Bravo-Osuna, M Vicario-De-La-Torre, V Andrés-Guerrero, ... Molecular pharmaceutics 13 (9), 2966-2976, 2016 | 66 | 2016 |
Interfacial interaction between transmembrane ocular mucins and adhesive polymers and dendrimers analyzed by surface plasmon resonance I Bravo-Osuna, M Noiray, E Briand, AM Woodward, P Argüeso, ... Pharmaceutical research 29, 2329-2340, 2012 | 66 | 2012 |
Specific permeability modulation of intestinal paracellular pathway by chitosan-poly (isobutylcyanoacrylate) core-shell nanoparticles I Bravo-Osuna, C Vauthier, H Chacun, G Ponchel European journal of pharmaceutics and biopharmaceutics 69 (2), 436-444, 2008 | 64 | 2008 |
Water sorption–desorption behaviour of methyl methacrylate–starch copolymers: effect of hydrophobic graft and drying method I Bravo-Osuna, C Ferrero, MR Jiménez-Castellanos European journal of pharmaceutics and biopharmaceutics 59 (3), 537-548, 2005 | 53 | 2005 |
Mineralocorticoid receptor antagonism limits experimental choroidal neovascularization and structural changes associated with neovascular age-related macular degeneration M Zhao, I Mantel, E Gelize, X Li, X Xie, A Arboleda, M Seminel, ... Nature communications 10 (1), 369, 2019 | 52 | 2019 |
Controlled delivery of tauroursodeoxycholic acid from biodegradable microspheres slows retinal degeneration and vision loss in P23H rats L Fernandez-Sanchez, I Bravo-Osuna, P Lax, A Arranz-Romera, V Maneu, ... PLoS One 12 (5), e0177998, 2017 | 51 | 2017 |
Optimising the controlled release of dexamethasone from a new generation of PLGA-based microspheres intended for intravitreal administration JR Villanueva, I Bravo-Osuna, R Herrero-Vanrell, ITM Martínez, ... European Journal of Pharmaceutical Sciences 92, 287-297, 2016 | 47 | 2016 |
Six month delivery of GDNF from PLGA/vitamin E biodegradable microspheres after intravitreal injection in rabbits C García-Caballero, E Prieto-Calvo, P Checa-Casalengua, ... European Journal of Pharmaceutical Sciences 103, 19-26, 2017 | 43 | 2017 |
Pharmaceutical microscope and nanoscale approaches for the efficient treatment of ocular diseases I Bravo-Osuna, V Andrés-Guerrero, P Pastoriza Abal, IT Molina-Martínez, ... Drug Delivery and Translational Research 92, 287, 2016 | 43 | 2016 |
Influence of moisture content on the mechanical properties of methyl methacrylate–starch copolymers I Bravo-Osuna, C Ferrero, MR Jiménez-Castellanos European journal of pharmaceutics and biopharmaceutics 66 (1), 63-72, 2007 | 40 | 2007 |