| How directed evolution reshapes the energy landscape in an enzyme to boost catalysis R Otten, RAP Pádua, HA Bunzel, V Nguyen, W Pitsawong, MK Patterson, ... Science 370 (6523), 1442-1446, 2020 | 128 | 2020 |
| Speeding up enzyme discovery and engineering with ultrahigh-throughput methods HA Bunzel, X Garrabou, M Pott, D Hilvert Current opinion in structural biology 48, 149-156, 2018 | 125 | 2018 |
| Evolution of dynamical networks enhances catalysis in a designer enzyme HA Bunzel, JLR Anderson, D Hilvert, VL Arcus, MW Van Der Kamp, ... Nature Chemistry 13 (10), 1017-1022, 2021 | 78 | 2021 |
| Designing better enzymes: Insights from directed evolution HA Bunzel, JLR Anderson, AJ Mulholland Current Opinion in Structural Biology 67, 212-218, 2021 | 61 | 2021 |
| Efficient Lewis acid catalysis of an abiological reaction in a de novo protein scaffold S Basler, S Studer, Y Zou, T Mori, Y Ota, A Camus, HA Bunzel, ... Nature Chemistry 13 (3), 231-235, 2021 | 60 | 2021 |
| Emergence of a negative activation heat capacity during evolution of a designed enzyme HA Bunzel, H Kries, L Marchetti, C Zeymer, PRE Mittl, AJ Mulholland, ... Journal of the American Chemical Society 141 (30), 11745-11748, 2019 | 45 | 2019 |
| Rigidifying a De Novo Enzyme Increases Activity and Induces a Negative Activation Heat Capacity SA Hindson, HA Bunzel, B Frank, DA Svistunenko, C Williams, ... ACS catalysis 11 (18), 11532-11541, 2021 | 16 | 2021 |
| Contribution of oxyanion stabilization to kemp eliminase efficiency H Kries, JS Bloch, HA Bunzel, DM Pinkas, D Hilvert ACS Catalysis 10 (8), 4460-4464, 2020 | 16 | 2020 |
| An expandable, modular de novo protein platform for precision redox engineering GH Hutchins, CEM Noble, HA Bunzel, C Williams, P Dubiel, SKN Yadav, ... Proceedings of the National Academy of Sciences 120 (31), e2306046120, 2023 | 2 | 2023 |
| Selection of a promiscuous minimalist cAMP phosphodiesterase from a library of de novo designed proteins JD Schnettler, MS Wang, M Gantz, HA Bunzel, C Karas, F Hollfelder, ... Nature Chemistry, 1-9, 2024 | 1 | 2024 |
| Epistasis arises from shifting the rate-limiting step during enzyme evolution of a β-lactamase C Fröhlich, HA Bunzel, K Buda, AJ Mulholland, MW Van der Kamp, ... Nature Catalysis, 1-11, 2024 | 1 | 2024 |
| Electric Fields Are a Key Determinant of Carbapenemase Activity in Class A β-Lactamases H Jabeen, M Beer, J Spencer, MW van der Kamp, HA Bunzel, ... ACS Catalysis 14, 7166-7172, 2024 | 1 | 2024 |
| In vitro generated antibodies guide thermostable ADDomer nanoparticle design for nasal vaccination and passive immunization against SARS-CoV-2 D Buzas, AH Bunzel, O Staufer, EJ Milodowski, GL Edmunds, JC Bufton, ... Antibody therapeutics 6 (4), 277-297, 2023 | 1 | 2023 |
| Comment on:“Computer Simulations Reveal an Entirely Entropic Activation Barrier for the Chemical Step in a Designer Enzyme” A Lear, JLR Anderson, D Hilvert, VL Arcus, MW van der Kamp, HA Bunzel, ... ACS Catalysis 13 (15), 10527-10530, 2023 | 1 | 2023 |
| Photovoltaic enzymes by design and evolution HA Bunzel, JA Smith, TAA Oliver, MR Jones, AJ Mulholland, ... bioRxiv, 2022.12. 20.521207, 2022 | 1 | 2022 |
| De Novo Enzyme Engineering: Directed Evolution of Computationally Designed Enzymes HA Bunzel ETH Zurich, 2018 | 1 | 2018 |
| Selection of a Promiscuous Minimalist cAMP Phosphodiesterase from a Library of De Novo Designed Proteins F Hollfelder, JD Schnettler, M Gantz, MS Wang, HA Bunzel, C Karas, ... Nature Research, 2023 | | 2023 |
| Epistasis Arises from Shifting the Rate-Limiting Step during Enzyme Evolution C Frohlich, HA Bunzel, K Buda, AJ Mulholland, MW van der Kamp, ... bioRxiv, 2023.06. 29.547057, 2023 | | 2023 |
| Beneficial substrate partitioning boosts non-aqueous catalysis in de novo enzyme-alginate beads R Stenner, H Adrian Bunzel, AJ Mulholland, JL Ross Anderson bioRxiv, 2021.04. 12.439416, 2021 | | 2021 |
| KN HOUK, G. JIMÉNEZ-OSÉS, D. HILVERT*(ETH ZÜRICH, SWITZERLAND; UNIVERSITY OF CALIFORNIA, LOS ANGELES, USA; BASQUE RESEARCH AND TECHNOLOGY ALLIANCE, DERIO, SPAIN) S BASLER, S STUDER, Y ZOU, T MORI, Y OTA, A CAMUS, HA BUNZEL, ... J. Am. Chem. Soc 143, 3003-3012, 2021 | | 2021 |
