Biomarkers and surrogate endpoints: preferred definitions and conceptual framework Biomarkers Definitions Working Group, AJ Atkinson Jr, WA Colburn, ... Clinical pharmacology & therapeutics 69 (3), 89-95, 2001 | 7324 | 2001 |
Modeling the relationship of survival to longitudinal data measured with error. Applications to survival and CD4 counts in patients with AIDS AA Tsiatis, V Degruttola, MS Wulfsohn Journal of the American statistical association 90 (429), 27-37, 1995 | 768 | 1995 |
Modelling progression of CD4-lymphocyte count and its relationship to survival time V De Gruttola, XM Tu Biometrics, 1003-1014, 1994 | 581 | 1994 |
Estimating the proportion of treatment effect explained by a surrogate marker DY Lin, TR Fleming, V De Gruttola Statistics in medicine 16 (13), 1515-1527, 1997 | 537 | 1997 |
Considerations in the evaluation of surrogate endpoints in clinical trials: summary of a National Institutes of Health workshop VG De Gruttola, P Clax, DL DeMets, GJ Downing, SS Ellenberg, ... Controlled clinical trials 22 (5), 485-502, 2001 | 507 | 2001 |
Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection GK Robbins, V De Gruttola, RW Shafer, LM Smeaton, SW Snyder, ... New England Journal of Medicine 349 (24), 2293-2303, 2003 | 473 | 2003 |
The relation between baseline HIV drug resistance and response to antiretroviral therapy: re-analysis of retrospective and prospective studies using a standardized data … V DeGruttola, L Dix, R D'Aquila, D Holder, A Phillips, M Ait-Khaled, ... Antiviral therapy 5 (1), 41-48, 2000 | 417 | 2000 |
Analysis of doubly-censored survival data, with application to AIDS V De Gruttola, SW Lagakos Biometrics 45 (1), 1-11, 1989 | 412 | 1989 |
Nonparametric analysis of truncated survival data, with application to AIDS SW Lagakos, LM Barraj, V Gruttola Biometrika 75 (3), 515-523, 1988 | 368 | 1988 |
Primary neural degeneration in the human cochlea: evidence for hidden hearing loss in the aging ear PZ Wu, LD Liberman, K Bennett, V De Gruttola, JT O'malley, MC Liberman Neuroscience 407, 8-20, 2019 | 340 | 2019 |
Use of changes in plasma levels of human immunodeficiency virus type 1 RNA to assess the clinical benefit of antiretroviral therapy IC Marschner, AC Collier, RW Coombs, RT D'Aquila, V DeGruttola, ... Journal of Infectious Diseases 177 (1), 40-47, 1998 | 319 | 1998 |
Pharmacogenetics of long-term responses to antiretroviral regimens containing efavirenz and/or nelfinavir: an Adult AIDS Clinical Trials Group study DW Haas, LM Smeaton, RW Shafer, GK Robbins, GD Morse, L Labbé, ... Journal of Infectious Diseases 192 (11), 1931-1942, 2005 | 313 | 2005 |
Comparison of four-drug regimens and pairs of sequential three-drug regimens as initial therapy for HIV-1 infection RW Shafer, LM Smeaton, GK Robbins, V De Gruttola, SW Snyder, ... New England Journal of Medicine 349 (24), 2304-2315, 2003 | 309 | 2003 |
Incubation periods for paediatric AIDS patients I Auger, P Thomas, V De Gruttola, D Morse, D Moore, R Williams, ... Nature 336 (6199), 575-577, 1988 | 288 | 1988 |
Zidovudine resistance and HIV-1 disease progression during antiretroviral therapy RT D'Aquila, VA Johnson, SL Welles, AJ Japour, DR Kuritzkes, ... Annals of internal medicine 122 (6), 401-408, 1995 | 285 | 1995 |
Botswana's progress toward achieving the 2020 UNAIDS 90-90-90 antiretroviral therapy and virological suppression goals: a population-based survey T Gaolathe, KE Wirth, MP Holme, J Makhema, S Moyo, U Chakalisa, ... The lancet HIV 3 (5), e221-e230, 2016 | 263 | 2016 |
Infectiousness of HIV between male homosexual partners V DeGruttola, GR Seage III, KH MAYER, CR Horsburgh Jr Journal of clinical epidemiology 42 (9), 849-856, 1989 | 261 | 1989 |
A flexible B-spline model for multiple longitudinal biomarkers and survival ER Brown, JG Ibrahim, V DeGruttola Biometrics 61 (1), 64-73, 2005 | 244 | 2005 |
Association of plasma human immunodeficiency virus type 1 RNA level with risk of clinical progression in patients with advanced infection RW Coombs, SL Welles, C Hooper, PA Reichelderfer, RT D'Aquila, ... Journal of Infectious Diseases 174 (4), 704-712, 1996 | 231 | 1996 |
Dual vs single protease inhibitor therapy following antiretroviral treatment failure: a randomized trial SM Hammer, F Vaida, KK Bennett, MK Holohan, L Sheiner, JJ Eron, ... Jama 288 (2), 169-180, 2002 | 206 | 2002 |