| Binding, uptake, and intracellular trafficking of phosphorothioate-modified oligodeoxynucleotides. C Beltinger, HU Saragovi, RM Smith, L LeSauteur, N Shah, L DeDionisio, ... The Journal of clinical investigation 95 (4), 1814-1823, 1995 | 399 | 1995 |
| Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease EJ Mufson, SY Ma, EJ Cochran, DA Bennett, LA Beckett, S Jaffar, ... Journal of Comparative Neurology 427 (1), 19-30, 2000 | 293 | 2000 |
| Reduction of cortical TrkA but not p75NTR protein in early‐stage Alzheimer's disease SE Counts, M Nadeem, J Wuu, SD Ginsberg, HU Saragovi, EJ Mufson Annals of Neurology: Official Journal of the American Neurological …, 2004 | 232 | 2004 |
| Design and synthesis of a mimetic from an antibody complementarity-determining region HU Saragovi, D Fitzpatrick, A Raktabutr, H Nakanishi, M Kahn, MI Greene Science 253 (5021), 792-795, 1991 | 229 | 1991 |
| Reduction in p140-TrkA receptor protein within the nucleus basalis and cortex in Alzheimer's disease EJ Mufson, N Lavine, S Jaffar, JH Kordower, R Quirion, HU Saragovi Experimental neurology 146 (1), 91-103, 1997 | 226 | 1997 |
| PBX and MEIS as non-DNA-binding partners in trimeric complexes with HOX proteins K Shanmugam, NC Green, I Rambaldi, HU Saragovi, MS Featherstone Molecular and cellular biology 19 (11), 7577-7588, 1999 | 207 | 1999 |
| Development of pharmacological agents for targeting neurotrophins and their receptors HU Saragovi, K Gehring Trends in pharmacological sciences 21 (3), 93-98, 2000 | 175 | 2000 |
| A designed peptidomimetic agonistic ligand of TrkA nerve growth factor receptors S Maliartchouk, Y Feng, L Ivanisevic, T Debeir, AC Cuello, K Burgess, ... Molecular pharmacology 57 (2), 385-391, 2000 | 171 | 2000 |
| Small peptide mimics of nerve growth factor bind TrkA receptors and affect biological responses L LeSauteur, L Wei, BF Gibbs, HU Saragovi Journal of Biological Chemistry 270 (12), 6564-6569, 1995 | 155 | 1995 |
| p75 Co-receptors regulate ligand-dependent and ligand-independent Trk receptor activation, in part by altering Trk docking subdomains MC Zaccaro, L Ivanisevic, P Perez, SO Meakin, HU Saragovi Journal of Biological Chemistry 276 (33), 31023-31029, 2001 | 144 | 2001 |
| Taxane-antibody conjugates afford potent cytotoxicity, enhanced solubility, and tumor target selectivity V Guillemard, HU Saragovi Cancer research 61 (2), 694-699, 2001 | 143 | 2001 |
| A nerve growth factor mimetic TrkA antagonist causes withdrawal of cortical cholinergic boutons in the adult rat T Debeir, HU Saragovi, AC Cuello Proceedings of the National Academy of Sciences 96 (7), 4067-4072, 1999 | 143 | 1999 |
| Long-lasting rescue of age-associated deficits in cognition and the CNS cholinergic phenotype by a partial agonist peptidomimetic ligand of TrkA MA Bruno, PBS Clarke, A Seltzer, R Quirion, K Burgess, AC Cuello, ... Journal of Neuroscience 24 (37), 8009-8018, 2004 | 123 | 2004 |
| Optimal nerve growth factor trophic signals mediated by synergy of TrkA and p75 receptor-specific ligands S Maliartchouk, HU Saragovi Journal of Neuroscience 17 (16), 6031-6037, 1997 | 123 | 1997 |
| Interleukin 2 regulates the activity of the lyn protein-tyrosine kinase in a B-cell line. T Torigoe, HU Saragovi, JC Reed Proceedings of the National Academy of Sciences 89 (7), 2674-2678, 1992 | 123 | 1992 |
| Chronic and acute models of retinal neurodegeneration TrkA activity are neuroprotective whereas p75NTR activity is neurotoxic through a paracrine mechanism Y Bai, P Dergham, H Nedev, J Xu, A Galan, JC Rivera, S ZhiHua, ... Journal of Biological Chemistry 285 (50), 39392-39400, 2010 | 122 | 2010 |
| An agonistic TrkB mAb causes sustained TrkB activation, delays RGC death, and protects the retinal structure in optic nerve axotomy and in glaucoma Y Bai, J Xu, F Brahimi, Y Zhuo, MV Sarunic, HU Saragovi Investigative ophthalmology & visual science 51 (9), 4722-4731, 2010 | 120 | 2010 |
| Inhibition of p75NTR in glia potentiates TrkA-mediated survival of injured retinal ganglion cells F Lebrun-Julien, B Morquette, A Douillette, HU Saragovi, A Di Polo Molecular and Cellular Neuroscience 40 (4), 410-420, 2009 | 120 | 2009 |
| A TrkA-selective, fast internalizing nerve growth factor-antibody complex induces trophic but not neuritogenic signals HU Saragovi, WH Zheng, S Maliartchouk, GM DiGugliemo, YR Mawal, ... Journal of Biological Chemistry 273 (52), 34933-34940, 1998 | 118 | 1998 |
| A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2α-mediated Rho/ROCK signaling pathway E Goupil, D Tassy, C Bourguet, C Quiniou, V Wisehart, D Pétrin, ... Journal of biological chemistry 285 (33), 25624-25636, 2010 | 117 | 2010 |
