| Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins PS Chae, SGF Rasmussen, RR Rana, K Gotfryd, R Chandra, MA Goren, ... Nature methods 7 (12), 1003-1008, 2010 | 521 | 2010 |
| Lessons from lactose permease L Guan, HR Kaback Annu. Rev. Biophys. Biomol. Struct. 35, 67-91, 2006 | 375 | 2006 |
| Structural determination of wild-type lactose permease L Guan, O Mirza, G Verner, S Iwata, HR Kaback Proceedings of the National Academy of Sciences 104 (39), 15294-15298, 2007 | 244 | 2007 |
| Structural evidence for induced fit and a mechanism for sugar/H+ symport in LacY O Mirza, L Guan, G Verner, S Iwata, HR Kaback The EMBO Journal 25 (6), 1177-1183, 2006 | 207 | 2006 |
| Identification of Essential Charged Residues in Transmembrane Segments of the Multidrug Transporter MexB ofPseudomonas aeruginosa L Guan, T Nakae Journal of bacteriology 183 (5), 1734-1739, 2001 | 157 | 2001 |
| Structure-based mechanism for Na+/melibiose symport by MelB SA Ethayathulla, SM Yousef, A Amin, G Leblanc, HR Kaback, L Guan Nature Communications 5 (Article number: 3009), doi:10.1038/ncomms4009, 2014 | 148 | 2014 |
| A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins PS Chae, SGF Rasmussen, RR Rana, K Gotfryd, AC Kruse, A Manglik, ... Chemistry–A European Journal 18 (31), 9485-9490, 2012 | 148 | 2012 |
| An approach to membrane protein structure without crystals PL Sorgen, Y Hu, L Guan, HR Kaback, ME Girvin Proceedings of the National Academy of Sciences 99 (22), 14037-14040, 2002 | 118 | 2002 |
| Manipulating phospholipids for crystallization of a membrane transport protein L Guan, IN Smirnova, G Verner, S Nagamori, HR Kaback Proceedings of the National Academy of Sciences 103 (6), 1723-1726, 2006 | 108 | 2006 |
| Opening and closing of the periplasmic gate in lactose permease Y Zhou, L Guan, JA Freites, HR Kaback Proceedings of the National Academy of Sciences 105 (10), 3774-3778, 2008 | 100 | 2008 |
| Membrane topology of the xenobiotic-exporting subunit, MexB, of the MexA, B-OprM extrusion pump in Pseudomonas aeruginosa L Guan, M Ehrmann, H Yoneyama, T Nakae Journal of Biological Chemistry 274 (15), 10517-10522, 1999 | 99 | 1999 |
| Crystal structure of lactose permease in complex with an affinity inactivator yields unique insight into sugar recognition V Chaptal, S Kwon, MR Sawaya, L Guan, HR Kaback, J Abramson Proceedings of the National Academy of Sciences 108 (23), 9361-9366, 2011 | 98 | 2011 |
| Aromatic stacking in the sugar binding site of the lactose permease L Guan, Y Hu, HR Kaback Biochemistry 42 (6), 1377-1382, 2003 | 80 | 2003 |
| Exploiting luminescence spectroscopy to elucidate the interaction between sugar and a tryptophan residue in the lactose permease of Escherichia coli JL Vázquez-Ibar, L Guan, M Svrakic, HR Kaback Proceedings of the National Academy of Sciences 100 (22), 12706-12711, 2003 | 69 | 2003 |
| Mechanism of melibiose/cation symport of the melibiose permease of Salmonella typhimurium L Guan, S Nurva, SP Ankeshwarapu Journal of biological chemistry 286 (8), 6367-6374, 2011 | 67 | 2011 |
| Site-directed alkylation of cysteine to test solvent accessibility of membrane proteins L Guan, H Ronald Kaback Nature protocols 2 (8), 2012-2017, 2007 | 62 | 2007 |
| Binding affinity of lactose permease is not altered by the H+ electrochemical gradient L Guan, HR Kaback Proceedings of the National Academy of Sciences 101 (33), 12148-12152, 2004 | 62 | 2004 |
| Surface-exposed positions in the transmembrane helices of the lactose permease of Escherichia coli determined by intermolecular thiol cross-linking L Guan, FD Murphy, HR Kaback Proceedings of the National Academy of Sciences 99 (6), 3475-3480, 2002 | 60 | 2002 |
| Highly branched pentasaccharide-bearing amphiphiles for membrane protein studies M Ehsan, Y Du, NJ Scull, E Tikhonova, J Tarrasch, JS Mortensen, ... Journal of the American Chemical Society 138 (11), 3789-3796, 2016 | 59 | 2016 |
| Maltose neopentyl glycol-3 (MNG-3) analogues for membrane protein study KH Cho, M Husri, A Amin, K Gotfryd, HJ Lee, J Go, JW Kim, CJ Loland, ... Analyst 140 (9), 3157-3163, 2015 | 56 | 2015 |
