Natural and induced CD4+ CD25+ cells educate CD4+ CD25− cells to develop suppressive activity: the role of IL-2, TGF-β, and IL-10 SG Zheng, JH Wang, JD Gray, H Soucier, DA Horwitz The Journal of Immunology 172 (9), 5213-5221, 2004 | 938 | 2004 |
IL-2 is essential for TGF-β to convert naive CD4+ CD25− cells to CD25+ Foxp3+ regulatory T cells and for expansion of these cells SG Zheng, J Wang, P Wang, JD Gray, DA Horwitz The Journal of Immunology 178 (4), 2018-2027, 2007 | 783 | 2007 |
Role of vitamin A in the immune system Z Huang, Y Liu, G Qi, D Brand, SG Zheng Journal of clinical medicine 7 (9), 258, 2018 | 616 | 2018 |
Generation ex vivo of TGF-β-producing regulatory T cells from CD4+ CD25− precursors SG Zheng, JD Gray, K Ohtsuka, S Yamagiwa, DA Horwitz The Journal of Immunology 169 (8), 4183-4189, 2002 | 594 | 2002 |
TGF-β requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+ CD25+ regulatory cells SG Zheng, JH Wang, W Stohl, KS Kim, JD Gray, DA Horwitz The Journal of Immunology 176 (6), 3321-3329, 2006 | 477 | 2006 |
Natural and TGF-β–induced Foxp3+ CD4+ CD25+ regulatory T cells are not mirror images of each other DA Horwitz, SG Zheng, JD Gray Trends in immunology 29 (9), 429-435, 2008 | 445 | 2008 |
Cutting edge: Foxp3+ CD4+ CD25+ regulatory T cells induced by IL-2 and TGF-β are resistant to Th17 conversion by IL-6 SG Zheng, J Wang, DA Horwitz The Journal of Immunology 180 (11), 7112-7116, 2008 | 428 | 2008 |
Vitamin D and chronic diseases H Wang, W Chen, D Li, X Yin, X Zhang, N Olsen, SG Zheng Aging and disease 8 (3), 346, 2017 | 424 | 2017 |
Role of TNF–TNF receptor 2 signal in regulatory T cells and its therapeutic implications S Yang, J Wang, DD Brand, SG Zheng Frontiers in immunology 9, 360533, 2018 | 347 | 2018 |
The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3 Z Chen, J Barbi, S Bu, HY Yang, Z Li, Y Gao, D Jinasena, J Fu, F Lin, ... Immunity 39 (2), 272-285, 2013 | 312 | 2013 |
The role of the combination of IL-2 and TGF-β or IL-10 in the generation and function of CD4+ CD25+ and CD8+regulatory T cell subsets DA Horwitz, SG Zheng, JD Gray Journal of Leucocyte Biology 74 (4), 471-478, 2003 | 302 | 2003 |
CD4+ and CD8+ regulatory T cells generated ex vivo with IL-2 and TGF-β suppress a stimulatory graft-versus-host disease with a lupus-like syndrome SG Zheng, JH Wang, MN Koss, F Quismorio, JD Gray, DA Horwitz The Journal of Immunology 172 (3), 1531-1539, 2004 | 294 | 2004 |
Hall of fame among pro-inflammatory cytokines: interleukin-6 gene and its transcriptional regulation mechanisms Y Luo, SG Zheng Frontiers in immunology 7, 236681, 2016 | 292 | 2016 |
Cutting edge: all-trans retinoic acid sustains the stability and function of natural regulatory T cells in an inflammatory milieu X Zhou, N Kong, J Wang, H Fan, H Zou, D Horwitz, D Brand, Z Liu, ... The Journal of Immunology 185 (5), 2675-2679, 2010 | 264 | 2010 |
Critical role of IL‐2 and TGF‐β in generation, function and stabilization of Foxp3+CD4+ Treg DA Horwitz, SG Zheng, J Wang, JD Gray European journal of immunology 38 (4), 912-915, 2008 | 254 | 2008 |
Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions L Lu, Q Lan, Z Li, X Zhou, J Gu, Q Li, J Wang, M Chen, Y Liu, Y Shen, ... Proceedings of the National Academy of Sciences 111 (33), E3432-E3440, 2014 | 231 | 2014 |
Advances in distinguishing natural from induced Foxp3+ regulatory T cells X Lin, M Chen, Y Liu, Z Guo, X He, D Brand, SG Zheng International journal of clinical and experimental pathology 6 (2), 116, 2013 | 226 | 2013 |
Role of SMAD and non-SMAD signals in the development of Th17 and regulatory T cells L Lu, J Wang, F Zhang, Y Chai, D Brand, X Wang, DA Horwitz, W Shi, ... The Journal of immunology 184 (8), 4295-4306, 2010 | 218 | 2010 |
Adoptive transfer of human gingiva‐derived mesenchymal stem cells ameliorates collagen‐induced arthritis via suppression of Th1 and Th17 cells and enhancement of regulatory T … M Chen, W Su, X Lin, Z Guo, J Wang, Q Zhang, D Brand, B Ryffel, ... Arthritis & Rheumatism 65 (5), 1181-1193, 2013 | 200 | 2013 |
Inflammasome–IL-1–Th17 response in allergic lung inflammation AG Besnard, D Togbe, I Couillin, Z Tan, SG Zheng, F Erard, M Le Bert, ... Journal of molecular cell biology 4 (1), 3-10, 2012 | 197 | 2012 |