Inflamm‐aging: an evolutionary perspective on immunosenescence C Franceschi, M Bonafè, S Valensin, F Olivieri, M De Luca, E Ottaviani, ... Annals of the new York Academy of Sciences 908 (1), 244-254, 2000 | 5706 | 2000 |
IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland P Sansone, G Storci, S Tavolari, T Guarnieri, C Giovannini, M Taffurelli, ... The Journal of clinical investigation 117 (12), 3988-4002, 2007 | 918 | 2007 |
Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer P Sansone, C Savini, I Kurelac, Q Chang, LB Amato, A Strillacci, ... Proceedings of the National Academy of Sciences 114 (43), E9066-E9075, 2017 | 677 | 2017 |
Bone marrow cells differentiate in cardiac cell lineages after infarction independently of cell fusion J Kajstura, M Rota, B Whang, S Cascapera, T Hosoda, C Bearzi, ... Circulation research 96 (1), 127-137, 2005 | 670 | 2005 |
Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans M Barbieri, M Bonafe, C Franceschi, G Paolisso American Journal of Physiology-Endocrinology and Metabolism 285 (5), E1064-E1071, 2003 | 598 | 2003 |
Human immunosenescence: the prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space C Franceschi, M Bonafe, S Valensin Vaccine 18 (16), 1717-1720, 2000 | 573 | 2000 |
The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis Q Chang, E Bournazou, P Sansone, M Berishaj, SP Gao, L Daly, J Wels, ... Neoplasia 15 (7), 848-IN45, 2013 | 507 | 2013 |
Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans G De Benedictis, G Rose, G Carrieri, M De Luca, E Falcone, G Passarino, ... The FASEB Journal 13 (12), 1532-1536, 1999 | 482 | 1999 |
The network and the remodeling theories of aging: historical background and new perspectives C Franceschi, S Valensin, M Bonafe, G Paolisso, AI Yashin, D Monti, ... Experimental gerontology 35 (6-7), 879-896, 2000 | 446 | 2000 |
Centenarians as a model for healthy aging C Franceschi, M Bonafè Biochemical Society Transactions 31 (2), 457-461, 2003 | 443 | 2003 |
Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an … M Bonafè, M Barbieri, F Marchegiani, F Olivieri, E Ragno, C Giampieri, ... The Journal of Clinical Endocrinology & Metabolism 88 (7), 3299-3304, 2003 | 396 | 2003 |
A gender–dependent genetic predisposition to produce high levels of IL‐6 is detrimental for longevity M Bonafè, F Olivieri, L Cavallone, S Giovagnetti, F Marchegiani, ... European journal of immunology 31 (8), 2357-2361, 2001 | 389 | 2001 |
Chronic inflammation and the effect of IGF-I on muscle strength and power in older persons M Barbieri, L Ferrucci, E Ragno, A Corsi, S Bandinelli, M Bonafé, F Olivieri, ... American Journal of Physiology-Endocrinology and Metabolism 284 (3), E481-E487, 2003 | 388 | 2003 |
Do men and women follow different trajectories to reach extreme longevity? C Franceschi, L Motta, S Valensin, R Rapisarda, A Franzone, M Berardelli, ... Aging Clinical and Experimental Research 12, 77-84, 2000 | 370 | 2000 |
Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly G Rose, S Dato, K Altomare, D Bellizzi, S Garasto, V Greco, G Passarino, ... Experimental gerontology 38 (10), 1065-1070, 2003 | 353 | 2003 |
Fibroblasts isolated from common sites of breast cancer metastasis enhance cancer cell growth rates and invasiveness in an interleukin-6–dependent manner AW Studebaker, G Storci, JL Werbeck, P Sansone, AK Sasser, S Tavolari, ... Cancer research 68 (21), 9087-9095, 2008 | 289 | 2008 |
Gender-specific association between− 1082 IL-10 promoter polymorphism and longevity D Lio, L Scola, A Crivello, G Colonna-Romano, G Candore, M Bonafe, ... Genes & Immunity 3 (1), 30-33, 2002 | 283 | 2002 |
p66Shc/Notch-3 interplay controls self-renewal and hypoxia survival in human stem/progenitor cells of the mammary gland expanded in vitro as mammospheres P Sansone, G Storci, C Giovannini, S Pandolfi, S Pianetti, M Taffurelli, ... Stem cells 25 (3), 807-815, 2007 | 236 | 2007 |
Inflammation, genetics, and longevity: further studies on the protective effects in men of IL-10− 1082 promoter SNP and its interaction with TNF-α− 308 promoter SNP D Lio, L Scola, A Crivello, G Colonna-Romano, G Candore, M Bonafè, ... Journal of medical genetics 40 (4), 296-299, 2003 | 232 | 2003 |
Interleukin-6 gene alleles affect the risk of Alzheimer’s disease and levels of the cytokine in blood and brain F Licastro, LME Grimaldi, M Bonafè, C Martina, F Olivieri, L Cavallone, ... Neurobiology of aging 24 (7), 921-926, 2003 | 228 | 2003 |