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Peter Howley
Peter Howley
Professor, Harvard Medical School
Bestätigte E-Mail-Adresse bei hms.harvard.edu
Titel
Zitiert von
Zitiert von
Jahr
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
M Scheffner, BA Werness, JM Huibregtse, AJ Levine, PM Howley
cell 63 (6), 1129-1136, 1990
52821990
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
N Dyson, PM Howley, K Münger, ED Harlow
Science 243 (4893), 934-937, 1989
40291989
Association of human papillomavirus types 16 and 18 E6 proteins with p53
BA Werness, AJ Levine, PM Howley
Science 248 (4951), 76-79, 1990
34391990
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
M Scheffner, JM Huibregtse, RD Vierstra, PM Howley
Cell 75 (3), 495-505, 1993
31191993
The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes
K Münger, WC Phelps, V Bubb, PM Howley, R Schlegel
Journal of virology 63 (10), 4417-4421, 1989
18341989
Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product.
K Münger, BA Werness, N Dyson, WC Phelps, E Harlow, PM Howley
The EMBO journal 8 (13), 4099-4105, 1989
15371989
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase.
JM Huibregtse, M Scheffner, S Beaudenon, PM Howley
Proceedings of the National Academy of Sciences 92 (7), 2563-2567, 1995
14831995
A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18.
JM Huibregtse, M Scheffner, PM Howley
The EMBO journal 10 (13), 4129-4135, 1991
11431991
Human papillomavirus immortalization and transformation functions
K Münger, PM Howley
Virus research 89 (2), 213-228, 2002
11422002
The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines.
M Scheffner, K Münger, JC Byrne, PM Howley
Proceedings of the National Academy of Sciences 88 (13), 5523-5527, 1991
10881991
Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines
CC Baker, WC Phelps, V Lindgren, MJ Braun, MA Gonda, PM Howley
Journal of virology 61 (4), 962-971, 1987
10041987
Virus infection induces the assembly of coordinately activated transcription factors on the IFN-β enhancer in vivo
MG Wathelet, CH Lin, BS Parekh, LV Ronco, PM Howley, T Maniatis
Molecular cell 1 (4), 507-518, 1998
9411998
In Vivo Ubiquitination and Proteasome-mediated Degradation of p53
CG Maki, JM Huibregtse, PM Howley
Cancer research 56 (11), 2649-2654, 1996
8751996
The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A
WC Phelps, CL Yee, K Münger, PM Howley
Cell 53 (4), 539-547, 1988
8741988
Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the …
S Chellappan, VB Kraus, B Kroger, K Munger, PM Howley, WC Phelps, ...
Proceedings of the National Academy of Sciences 89 (10), 4549-4553, 1992
8471992
Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity
LV Ronco, AY Karpova, M Vidal, PM Howley
Genes & development 12 (13), 2061-2072, 1998
8021998
Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines.
C Yee, I Krishnan-Hewlett, CC Baker, R Schlegel, PM Howley
The American journal of pathology 119 (3), 361, 1985
7841985
Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade
L Huang, E Kinnucan, G Wang, S Beaudenon, PM Howley, JM Huibregtse, ...
Science 286 (5443), 1321-1326, 1999
7611999
Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53
JM Huibregtse, M Scheffner, PM Howley
Molecular and cellular biology, 1993
7421993
TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains
JA Pietenpol, RW Stein, E Moran, P Yaciuk, R Schlegel, RM Lyons, ...
Cell 61 (5), 777-785, 1990
7391990
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