Aurelio Lorico
Aurelio Lorico
Professor of Pathology, Touro University College of Medicine
Verified email at - Homepage
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Evidence that the multidrug resistance protein (MRP) functions as a co-transporter of glutathione and natural product toxins
G Rappa, A Lorico, RA Flavell, AC Sartorelli
Cancer research 57 (23), 5232-5237, 1997
Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione
A Lorico, G Rappa, RA Finch, D Yang, RA Flavell, AC Sartorelli
Cancer research 57 (23), 5238-5242, 1997
The stem cell‐associated antigen CD133 (Prominin‐1) is a molecular therapeutic target for metastatic melanoma
G Rappa, O Fodstad, A Lorico
Stem cells 26 (12), 3008-3017, 2008
Inhibitors of ribonucleotide reductase: Comparative effects of amino-and hydroxy-substituted pyridine-2-carboxaldehydethiosemicarbazones
JG Cory, AH Cory, G Rappa, A Lorico, L Mao-Chin, L Tai-Shun, ...
Biochemical pharmacology 48 (2), 335-344, 1994
Mechanisms of resistance to etoposide and teniposide in acquired resistant human colon and lung carcinoma cell lines
BH Long, L Wang, A Lorico, RCC Wang, MG Brattain, AM Casazza
Cancer research 51 (19), 5275-5283, 1991
Double knockout of the MRP gene leads to increased drug sensitivity in vitro
A Lorico, G Rappa, RA Flavell, AC Sartorelli
Cancer research 56 (23), 5351-5355, 1996
New insights into the biology and pharmacology of the multidrug resistance protein (MRP) from gene knockout models.
G Rappa, RA Finch, AC Sartorelli, A Lorico
Biochemical pharmacology 58 (4), 557-562, 1999
Accumulation of DNA strand breaks in cells exposed to methotrexate or N10-propargyl-5, 8-dideazafolic acid
A Lorico, G Toffoli, M Boiocchi, E Erba, M Broggini, G Rappa, M D'Incalci
Cancer Research 48 (8), 2036-2041, 1988
Apparent lack of Mrp1-mediated efflux at the luminal side of mouse blood-brain barrier endothelial cells
S Cisternino, C Rousselle, A Lorico, G Rappa, JM Scherrmann
Pharmaceutical research 20 (6), 904-909, 2003
Growth of cancer cell lines under stem cell-like conditions has the potential to unveil therapeutic targets
G Rappa, J Mercapide, F Anzanello, L Prasmickaite, Y Xi, J Ju, O Fodstad, ...
Experimental cell research 314 (10), 2110-2122, 2008
Biochemical and biological characterization of exosomes containing prominin-1/CD133
G Rappa, J Mercapide, F Anzanello, RM Pope, A Lorico
Molecular cancer 12 (1), 1-17, 2013
Spontaneous formation of tumorigenic hybrids between breast cancer and multipotent stromal cells is a source of tumor heterogeneity
G Rappa, J Mercapide, A Lorico
The American journal of pathology 180 (6), 2504-2515, 2012
Phenotypic heterogeneity of breast cancer stem cells
A Lorico, G Rappa
Journal of oncology 2011, 2011
Erythrocyte membrane ATP binding cassette (ABC) proteins: MRP1 and CFTR as well as CD39 (ecto-apyrase) involved in RBC ATP transport and elevated blood plasma ATP of cystic …
EH Abraham, KM Sterling, RJ Kim, AY Salikhova, HB Huffman, ...
Blood Cells, Molecules, and Diseases 27 (1), 165-180, 2001
Clinical significance of extracellular vesicles in plasma from glioblastoma patients
D Osti, M Del Bene, G Rappa, M Santos, V Matafora, C Richichi, S Faletti, ...
Clinical Cancer Research 25 (1), 266-276, 2019
Extracellular vesicle-mediated transfer of CLIC1 protein is a novel mechanism for the regulation of glioblastoma growth
M Setti, D Osti, C Richichi, B Ortensi, M Del Bene, L Fornasari, ...
Oncotarget 6 (31), 31413, 2015
Biochemical characterisation of elsamicin and other coumarin-related antitumour agents as potent inhibitors of human topoisomerase II
A Lorico, BH Long
European Journal of Cancer 29 (14), 1985-1991, 1993
Role of the Multidrug Resistance Protein 1 in Protection from Heavy Metal Oxyanions: Investigations in Vitro and in MRP1-Deficient Mice
A Lorico, A Bertola, C Baum, O Fodstad, G Rappa
Biochemical and biophysical research communications 291 (3), 617-622, 2002
Structure-function relationships for a new series of pyridine-2-carboxaldehyde thiosemicarbazones on ribonucleotide reductase activity and tumor cell growth in culture and in vivo
JG Cory, AH Cory, G Rappa, A Lorico, MC Llu, TS Lin, AC Sartorelli
Advances in enzyme regulation 35, 55-68, 1995
Wnt interaction and extracellular release of prominin-1/CD133 in human malignant melanoma cells
G Rappa, J Mercapide, F Anzanello, TT Le, MG Johlfs, RR Fiscus, ...
Experimental cell research 319 (6), 810-819, 2013
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