| Evidence that the multidrug resistance protein (MRP) functions as a co-transporter of glutathione and natural product toxins G Rappa, A Lorico, RA Flavell, AC Sartorelli Cancer research 57 (23), 5232-5237, 1997 | 355 | 1997 |
| Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione A Lorico, G Rappa, RA Finch, D Yang, RA Flavell, AC Sartorelli Cancer research 57 (23), 5238-5242, 1997 | 293 | 1997 |
| The stem cell‐associated antigen CD133 (Prominin‐1) is a molecular therapeutic target for metastatic melanoma G Rappa, O Fodstad, A Lorico Stem cells 26 (12), 3008-3017, 2008 | 252 | 2008 |
| Inhibitors of ribonucleotide reductase: Comparative effects of amino-and hydroxy-substituted pyridine-2-carboxaldehydethiosemicarbazones JG Cory, AH Cory, G Rappa, A Lorico, L Mao-Chin, L Tai-Shun, ... Biochemical pharmacology 48 (2), 335-344, 1994 | 126 | 1994 |
| Mechanisms of resistance to etoposide and teniposide in acquired resistant human colon and lung carcinoma cell lines BH Long, L Wang, A Lorico, RCC Wang, MG Brattain, AM Casazza Cancer research 51 (19), 5275-5283, 1991 | 120 | 1991 |
| Double knockout of the MRP gene leads to increased drug sensitivity in vitro A Lorico, G Rappa, RA Flavell, AC Sartorelli Cancer research 56 (23), 5351-5355, 1996 | 106 | 1996 |
| New insights into the biology and pharmacology of the multidrug resistance protein (MRP) from gene knockout models. G Rappa, RA Finch, AC Sartorelli, A Lorico Biochemical pharmacology 58 (4), 557-562, 1999 | 89 | 1999 |
| Accumulation of DNA strand breaks in cells exposed to methotrexate or N10-propargyl-5, 8-dideazafolic acid A Lorico, G Toffoli, M Boiocchi, E Erba, M Broggini, G Rappa, M D'Incalci Cancer Research 48 (8), 2036-2041, 1988 | 87 | 1988 |
| Apparent lack of Mrp1-mediated efflux at the luminal side of mouse blood-brain barrier endothelial cells S Cisternino, C Rousselle, A Lorico, G Rappa, JM Scherrmann Pharmaceutical research 20 (6), 904-909, 2003 | 86 | 2003 |
| Growth of cancer cell lines under stem cell-like conditions has the potential to unveil therapeutic targets G Rappa, J Mercapide, F Anzanello, L Prasmickaite, Y Xi, J Ju, O Fodstad, ... Experimental cell research 314 (10), 2110-2122, 2008 | 84 | 2008 |
| Biochemical and biological characterization of exosomes containing prominin-1/CD133 G Rappa, J Mercapide, F Anzanello, RM Pope, A Lorico Molecular cancer 12 (1), 1-17, 2013 | 83 | 2013 |
| Spontaneous formation of tumorigenic hybrids between breast cancer and multipotent stromal cells is a source of tumor heterogeneity G Rappa, J Mercapide, A Lorico The American journal of pathology 180 (6), 2504-2515, 2012 | 82 | 2012 |
| Phenotypic heterogeneity of breast cancer stem cells A Lorico, G Rappa Journal of oncology 2011, 2011 | 77 | 2011 |
| Erythrocyte membrane ATP binding cassette (ABC) proteins: MRP1 and CFTR as well as CD39 (ecto-apyrase) involved in RBC ATP transport and elevated blood plasma ATP of cystic … EH Abraham, KM Sterling, RJ Kim, AY Salikhova, HB Huffman, ... Blood Cells, Molecules, and Diseases 27 (1), 165-180, 2001 | 77 | 2001 |
| Clinical significance of extracellular vesicles in plasma from glioblastoma patients D Osti, M Del Bene, G Rappa, M Santos, V Matafora, C Richichi, S Faletti, ... Clinical Cancer Research 25 (1), 266-276, 2019 | 69 | 2019 |
| Extracellular vesicle-mediated transfer of CLIC1 protein is a novel mechanism for the regulation of glioblastoma growth M Setti, D Osti, C Richichi, B Ortensi, M Del Bene, L Fornasari, ... Oncotarget 6 (31), 31413, 2015 | 64 | 2015 |
| Biochemical characterisation of elsamicin and other coumarin-related antitumour agents as potent inhibitors of human topoisomerase II A Lorico, BH Long European Journal of Cancer 29 (14), 1985-1991, 1993 | 57 | 1993 |
| Role of the Multidrug Resistance Protein 1 in Protection from Heavy Metal Oxyanions: Investigations in Vitro and in MRP1-Deficient Mice A Lorico, A Bertola, C Baum, O Fodstad, G Rappa Biochemical and biophysical research communications 291 (3), 617-622, 2002 | 51 | 2002 |
| Structure-function relationships for a new series of pyridine-2-carboxaldehyde thiosemicarbazones on ribonucleotide reductase activity and tumor cell growth in culture and in vivo JG Cory, AH Cory, G Rappa, A Lorico, MC Llu, TS Lin, AC Sartorelli Advances in enzyme regulation 35, 55-68, 1995 | 47 | 1995 |
| Wnt interaction and extracellular release of prominin-1/CD133 in human malignant melanoma cells G Rappa, J Mercapide, F Anzanello, TT Le, MG Johlfs, RR Fiscus, ... Experimental cell research 319 (6), 810-819, 2013 | 46 | 2013 |
Oystein fodstadProfessor emeritus, Oslo University Hospital, University of OsloVerified email at rr-research.no
