| Oxygen battle in the gut: Hypoxia and hypoxia-inducible factors in metabolic and inflammatory responses in the intestine R Singhal, YM Shah Journal of Biological Chemistry 295 (30), 10493-10505, 2020 | 212 | 2020 |
| Platelet activation determines the severity of thrombocytopenia in dengue infection A Ojha, D Nandi, H Batra, R Singhal, GK Annarapu, S Bhattacharyya, ... Scientific reports 7 (1), 41697, 2017 | 161 | 2017 |
| HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron R Singhal, SR Mitta, NK Das, SA Kerk, P Sajjakulnukit, S Solanki, ... The Journal of clinical investigation 131 (12), 2021 | 126 | 2021 |
| Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance HN Bell, RJ Rebernick, J Goyert, R Singhal, M Kuljanin, SA Kerk, ... Cancer cell 40 (2), 185-200. e6, 2022 | 110 | 2022 |
| Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells AJ Schwartz, JW Goyert, S Solanki, SA Kerk, B Chen, C Castillo, PP Hsu, ... Nature metabolism 3 (7), 969-982, 2021 | 61 | 2021 |
| Hemoglobin interaction with GP1bα induces platelet activation and apoptosis: a novel mechanism associated with intravascular hemolysis R Singhal, GK Annarapu, A Pandey, S Chawla, A Ojha, A Gupta, MA Cruz, ... Haematologica 100 (12), 1526, 2015 | 52 | 2015 |
| Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer HN Bell, AK Huber, R Singhal, N Korimerla, RJ Rebernick, R Kumar, ... Cell metabolism 35 (1), 134-149. e6, 2023 | 29 | 2023 |
| HbS binding to GP1bα activates platelets in sickle cell disease GK Annarapu, R Singhal, A Gupta, S Chawla, H Batra, T Seth, P Guchhait PLoS One 11 (12), e0167899, 2016 | 25 | 2016 |
| Development of pro-inflammatory phenotype in monocytes after engulfing Hb-activated platelets in hemolytic disorders R Singhal, S Chawla, DK Rathore, A Bhasym, GK Annarapu, V Sharma, ... Clinical Immunology 175, 133-142, 2017 | 23 | 2017 |
| Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress SN Devenport, R Singhal, MD Radyk, JG Taranto, SA Kerk, B Chen, ... JCI insight 6 (14), 2021 | 21 | 2021 |
| Engulfment of Hb‐activated platelets differentiates monocytes into pro‐inflammatory macrophages in PNH patients R Singhal, S Chawla, H Batra, S Gupta, A Ojha, DK Rathore, T Seth, ... European Journal of Immunology 48 (8), 1285-1294, 2018 | 8 | 2018 |
| PTEN-induced kinase PINK1 supports colorectal cancer growth by regulating the labile iron pool B Chen, NK Das, I Talukder, R Singhal, C Castillo, A Andren, JD Mancias, ... Journal of Biological Chemistry 299 (5), 2023 | 7 | 2023 |
| Inhibition of Hb binding to GP1bα abrogates Hb-mediated thrombus formation on immobilized VWF and collagen under physiological shear stress GK Annarapu, R Singhal, Y Peng, P Guchhait PloS one 11 (4), e0154276, 2016 | 7 | 2016 |
| Hypoxia inducible factor-2α increases sensitivity of colon cancer cells towards oxidative cell death R Singhal, SR Mitta, KP Olive, CA Lyssiotis, YM Shah BioRxiv, 823997, 2019 | 3 | 2019 |
| Absence of nonclassical monocytes in hemolytic patients: free hb and no-mediated mechanism R Singhal, DK Rathore, T Bhakuni, T Seth, P Guchhait Journal of Immunology Research 2019, 2019 | 3 | 2019 |
| Sulfide oxidation promotes hypoxic angiogenesis and neovascularization R Kumar, V Vitvitsky, A Sethaudom, R Singhal, S Solanki, S Alibeckoff, ... Nature Chemical Biology, 1-11, 2024 | 1 | 2024 |
| Disruption of hypoxia-inducible factor-2α in neutrophils decreases colitis-associated colon cancer R Singhal, NK Kotla, S Solanki, W Huang, HN Bell, MO El-Derany, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 326 (1 …, 2024 | 1 | 2024 |
| Unique case of autoantibody mediated inactivation of ADAMTS13 in an Indian TTP patient T Bhakuni, R Singhal, GK Annarapu, A Sharma, M Mahapatra, R Saxena, ... Blood Cells, Molecules, and Diseases 77, 29-33, 2019 | 1 | 2019 |
| Hemoglobin Mediated Regulation of Platelet Functions GK Annarapu, R Singhal, S Chawla, A Ojha, P Guchhait | 1 | 2016 |
| Myeloid Hif2α is not essential to maintain systemic iron homeostasis C Jain, S Parimi, W Huang, S Hannifin, R Singhal, NK Das, KE Lee, ... Experimental Hematology 125, 25-36. e1, 2023 | | 2023 |
