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Catherine Leimkuhler Grimes
Catherine Leimkuhler Grimes
Assistant Professor University of Delaware
Verified email at udel.edu - Homepage
Title
Cited by
Cited by
Year
Glycopeptide and lipoglycopeptide antibiotics
D Kahne, C Leimkuhler, W Lu, C Walsh
Chemical reviews 105 (2), 425-448, 2005
8272005
The innate immune protein Nod2 binds directly to MDP, a bacterial cell wall fragment
CL Grimes, LDZ Ariyananda, JE Melnyk, EK O’Shea
Journal of the American Chemical Society 134 (33), 13535-13537, 2012
2232012
Metabolic labelling of the carbohydrate core in bacterial peptidoglycan and its applications
H Liang, KE DeMeester, CW Hou, MA Parent, JL Caplan, CL Grimes
Nature communications 8 (1), 15015, 2017
1362017
A systematic investigation of the synthetic utility of glycopeptide glycosyltransferases
M Oberthür, C Leimkuhler, RG Kruger, W Lu, CT Walsh, D Kahne
Journal of the American Chemical Society 127 (30), 10747-10752, 2005
1002005
AknT is an activating protein for the glycosyltransferase AknS in L-aminodeoxysugar transfer to the aglycone of aclacinomycin A
W Lu, C Leimkuhler, GJ Gatto, RG Kruger, M Oberthu, D Kahne, CT Walsh
Chemistry & biology 12 (5), 527-534, 2005
882005
Characterization of a regiospecific epivancosaminyl transferase GtfA and enzymatic reconstitution of the antibiotic chloroeremomycin
W Lu, M Oberthür, C Leimkuhler, J Tao, D Kahne, CT Walsh
Proceedings of the National Academy of Sciences 101 (13), 4390-4395, 2004
742004
Synthesis of Functionalized N-Acetyl Muramic Acids To Probe Bacterial Cell Wall Recycling and Biosynthesis
KE DeMeester, H Liang, MR Jensen, ZS Jones, EA D’Ambrosio, SL Scinto, ...
Journal of the American Chemical Society 140 (30), 9458-9465, 2018
662018
AknK is an L-2-deoxyfucosyltransferase in the biosynthesis of the anthracycline aclacinomycin A
W Lu, C Leimkuhler, M Oberthür, D Kahne, CT Walsh
Biochemistry 43 (15), 4548-4558, 2004
662004
In vitro reconstitution of EryCIII activity for the preparation of unnatural macrolides
Y Yuan, HS Chung, C Leimkuhler, CT Walsh, D Kahne, S Walker
Journal of the American Chemical Society 127 (41), 14128-14129, 2005
652005
Kinetic Characterization of the Glycosyltransferase Module of Staphylococcus aureus PBP2
D Barrett, C Leimkuhler, L Chen, D Walker, D Kahne, S Walker
Journal of bacteriology 187 (6), 2215-2217, 2005
642005
Differential inhibition of Staphylococcus aureus PBP2 by glycopeptide antibiotics
C Leimkuhler, L Chen, D Barrett, G Panzone, B Sun, B Falcone, ...
Journal of the American Chemical Society 127 (10), 3250-3251, 2005
592005
Distinct cytoskeletal proteins define zones of enhanced cell wall synthesis in Helicobacter pylori
JA Taylor, BP Bratton, SR Sichel, KM Blair, HM Jacobs, KE DeMeester, ...
elife 9, e52482, 2020
582020
Degradation and reconstruction of moenomycin A and derivatives: dissecting the function of the isoprenoid chain
M Adachi, Y Zhang, C Leimkuhler, B Sun, JV LaTour, DE Kahne
Journal of the American Chemical Society 128 (43), 14012-14013, 2006
582006
Molecular recognition of muramyl dipeptide occurs in the leucine-rich repeat domain of Nod2
ML Lauro, EA D’Ambrosio, BJ Bahnson, CL Grimes
ACS infectious diseases 3 (4), 264-270, 2017
542017
A two-track model for the spatiotemporal coordination of bacterial septal cell wall synthesis revealed by single-molecule imaging of FtsW
X Yang, R McQuillen, Z Lyu, P Phillips-Mason, A De La Cruz, ...
Nature microbiology 6 (5), 584-593, 2021
532021
Peptidoglycan modifications tune the stability and function of the innate immune receptor Nod2
JE Melnyk, V Mohanan, AK Schaefer, CW Hou, CL Grimes
Journal of the American Chemical Society 137 (22), 6987-6990, 2015
532015
A practical method for the stereoselective generation of β-2-deoxy glycosyl phosphates
M Oberthür, C Leimkuhler, D Kahne
Organic Letters 6 (17), 2873-2876, 2004
482004
The molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn disease
V Mohanan, CL Grimes
Journal of Biological Chemistry 289 (27), 18987-18998, 2014
452014
Characterization of rhodosaminyl transfer by the AknS/AknT glycosylation complex and its use in reconstituting the biosynthetic pathway of aclacinomycin A
C Leimkuhler, M Fridman, T Lupoli, S Walker, CT Walsh, D Kahne
Journal of the American Chemical Society 129 (34), 10546-10550, 2007
402007
Bacterial peptidoglycan fragments differentially regulate innate immune signaling
KL Bersch, KE DeMeester, R Zagani, S Chen, KA Wodzanowski, S Liu, ...
ACS central science 7 (4), 688-696, 2021
392021
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