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Jianping Guo
Jianping Guo
BIDMC, Harvard Medical School
Bestätigte E-Mail-Adresse bei BIDMC.HARVARD.EDU
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Zitiert von
Zitiert von
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Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance
J Zhang, X Bu, H Wang, Y Zhu, Y Geng, NT Nihira, Y Tan, Y Ci, F Wu, ...
Nature 553 (7686), 91-95, 2018
7772018
PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex
P Liu, W Gan, YR Chin, K Ogura, J Guo, J Zhang, B Wang, J Blenis, ...
Cancer discovery 5 (11), 1194-1209, 2015
3982015
Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4
X Dai, W Gan, X Li, S Wang, W Zhang, L Huang, S Liu, Q Zhong, J Guo, ...
Nature medicine 23 (9), 1063-1071, 2017
2802017
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
J Guo, AA Chakraborty, P Liu, W Gan, X Zheng, H Inuzuka, B Wang, ...
Science 353 (6302), 929-932, 2016
1812016
TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling
B Wang, Z Jie, D Joo, A Ordureau, P Liu, W Gan, J Guo, J Zhang, BJ North, ...
Nature 545 (7654), 365-369, 2017
1542017
Analysis of PD1, PDL1, PDL2 expression and T cells infiltration in 1014 gastric cancer patients
X Xing, J Guo, G Ding, B Li, B Dong, Q Feng, S Li, J Zhang, X Ying, ...
Oncoimmunology 7 (3), e1356144, 2018
1332018
AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions
J Guo, X Dai, B Laurent, N Zheng, W Gan, J Zhang, A Guo, M Yuan, P Liu, ...
Nature cell biology 21 (2), 226-237, 2019
1142019
Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade
X Dai, X Bu, Y Gao, J Guo, J Hu, C Jiang, Z Zhang, K Xu, J Duan, S He, ...
Molecular cell 81 (11), 2317-2331. e6, 2021
1132021
The emerging roles of protein homeostasis‐governing pathways in Alzheimer's disease
J Cheng, BJ North, T Zhang, X Dai, K Tao, J Guo, W Wei
Aging cell 17 (5), e12801, 2018
1052018
Inhibition of Rb phosphorylation leads to mTORC2-mediated activation of Akt
J Zhang, K Xu, P Liu, Y Geng, B Wang, W Gan, J Guo, F Wu, YR Chin, ...
Molecular cell 62 (6), 929-942, 2016
1042016
The potent roles of salt-inducible kinases (SIKs) in metabolic homeostasis and tumorigenesis
Z Sun, Q Jiang, J Li, J Guo
Signal transduction and targeted therapy 5 (1), 150, 2020
902020
Copper Promotes Tumorigenesis by Activating the PDK1‐AKT Oncogenic Pathway in a Copper Transporter 1 Dependent Manner
J Guo, J Cheng, N Zheng, X Zhang, X Dai, L Zhang, C Hu, X Wu, Q Jiang, ...
Advanced science 8 (18), 2004303, 2021
802021
Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair
P Liu, W Gan, C Guo, A Xie, D Gao, J Guo, J Zhang, N Willis, A Su, ...
Molecular cell 57 (4), 648-661, 2015
752015
Functional analysis of Cullin 3 E3 ligases in tumorigenesis
J Cheng, J Guo, Z Wang, BJ North, K Tao, X Dai, W Wei
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1869 (1), 11-28, 2018
692018
LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control
W Gan, X Dai, X Dai, J Xie, S Yin, J Zhu, C Wang, Y Liu, J Guo, M Wang, ...
Nature cell biology 22 (2), 246-256, 2020
682020
New insights into protein hydroxylation and its important role in human diseases
G Zurlo, J Guo, M Takada, W Wei, Q Zhang
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1866 (2), 208-220, 2016
642016
Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle
J Liu, Y Peng, LE Shi, L Wan, H Inuzuka, J Long, J Guo, J Zhang, M Yuan, ...
Cell research 31 (1), 80-93, 2021
602021
Functional analyses of major cancer-related signaling pathways in Alzheimer's disease etiology
J Guo, J Cheng, BJ North, W Wei
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1868 (2), 341-358, 2017
592017
Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells
L Zhang, S Peng, X Dai, W Gan, X Nie, W Wei, G Hu, J Guo
Cancer letters 390, 11-20, 2017
552017
The emerging role for Cullin 4 family of E3 ligases in tumorigenesis
J Cheng, J Guo, BJ North, K Tao, P Zhou, W Wei
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1871 (1), 138-159, 2019
542019
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