Cyclooxygenase‐1 haplotype modulates platelet response to aspirin AO Maree, RJ Curtin, A Chubb, C Dolan, D Cox, J O'brien, P Crean, ... Journal of Thrombosis and Haemostasis 3 (10), 2340-2345, 2005 | 325 | 2005 |
Open source drug discovery with the malaria box compound collection for neglected diseases and beyond WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ... PLoS pathogens 12 (7), e1005763, 2016 | 294 | 2016 |
Elucidating the role of Staphylococcus epidermidis serine–aspartate repeat protein G in platelet activation MP Brennan, A Loughman, M Devocelle, S Arasu, AJ Chubb, TJ Foster, ... Journal of thrombosis and haemostasis 7 (8), 1364-1372, 2009 | 108 | 2009 |
RN181, a novel ubiquitin E3 ligase that interacts with the KVGFFKR motif of platelet integrin αIIbβ3 TM Brophy, M Raab, H Daxecker, KG Culligan, I Lehmann, AJ Chubb, ... Biochemical and biophysical research communications 369 (4), 1088-1093, 2008 | 52 | 2008 |
Roles of the juxtamembrane and extracellular domains of angiotensin-converting enzyme in ectodomain shedding S PANG, AJ CHUBB, SLU SCHWAGER, MRW EHLERS, ED STURROCK, ... Biochemical Journal 358 (1), 185-192, 2001 | 48 | 2001 |
CycloPs: generating virtual libraries of cyclized and constrained peptides including nonnatural amino acids FJ Duffy, M Verniere, M Devocelle, E Bernard, DC Shields, AJ Chubb Journal of chemical information and modeling 51 (4), 829-836, 2011 | 46 | 2011 |
Modulation of juxtamembrane cleavage (“shedding”) of angiotensin-converting enzyme by stalk glycosylation: evidence for an alternative shedding protease SLU Schwager, AJ Chubb, RR Scholle, WF Brandt, R Mentele, ... Biochemistry 38 (32), 10388-10397, 1999 | 41 | 1999 |
A novel platinum complex of the histone deacetylase inhibitor belinostat: rational design, development and in vitro cytotoxicity JP Parker, H Nimir, DM Griffith, B Duff, AJ Chubb, MP Brennan, ... Journal of Inorganic Biochemistry 124, 70-77, 2013 | 36 | 2013 |
Monoclonal antibodies 1B3 and 5C8 as probes for monitoring the integrity of the C-terminal end of soluble angiotensin-converting enzyme IV Balyasnikova, ZL Sun, FE Franke, YV Berestetskaya, AJ Chubb, ... Hybridoma 24 (1), 14-26, 2005 | 32 | 2005 |
Homologous substitution of ACE C-domain regions with N-domain sequences: effect on processing, shedding, and catalytic properties ZL Woodman, SLU Schwager, P Redelinghuys, AJ Chubb, ... Walter de Gruyter 387 (8), 1043-1051, 2006 | 31 | 2006 |
The productive conformation of prostaglandin G2 at the peroxidase site of prostaglandin endoperoxide H synthase: docking, molecular dynamics, and site-directed mutagenesis studies AJ Chubb, DJ Fitzgerald, KB Nolan, E Moman Biochemistry 45 (3), 811-820, 2006 | 27 | 2006 |
Defining the boundaries of the testis angiotensin I-converting enzyme ectodomain AJ Chubb, SLU Schwager, ZL Woodman, MRW Ehlers, ED Sturrock Biochemical and biophysical research communications 297 (5), 1225-1230, 2002 | 24 | 2002 |
Identification of Mycobacterium tuberculosis signal sequences that direct the export of a leaderless β-lactamase gene product in Escherichia coli AJ Chubb, ZL Woodman, FMPR da Silva Tatley, HJ Hoffmann, ... Microbiology 144 (6), 1619-1629, 1998 | 24 | 1998 |
The present state of aspirin and clopidogrel resistance KE Guyer Hämostaseologie 29 (03), 285-290, 2009 | 23 | 2009 |
Integrated computational prediction and experimental validation identifies promiscuous T cell epitopes in the proteome of Mycobacterium bovis D Farrell, G Jones, C Pirson, K Malone, K Rue-Albrecht, AJ Chubb, ... Microbial genomics 2 (8), e000071, 2016 | 22 | 2016 |
Phorbol ester-induced juxtamembrane cleavage of angiotensin-converting enzyme is not inhibited by a stalk containing intrachain disulfides SLU Schwager, AJ Chubb, RR Scholle, WF Brandt, C Eckerskorn, ... Biochemistry 37 (44), 15449-15456, 1998 | 22 | 1998 |
Recombinant PAPP-A resistant insulin-like growth factor binding protein 4 (dBP4) inhibits angiogenesis and metastasis in a murine model of breast cancer YE Smith, S Toomey, S Napoletano, G Kirwan, C Schadow, AJ Chubb, ... BMC cancer 18, 1-12, 2018 | 20 | 2018 |
BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer S Shields, E Conroy, T O’Grady, A McGoldrick, K Connor, MP Ward, ... Oncotarget 9 (21), 15673, 2018 | 20 | 2018 |
Parallel synthesis and in vitro activity of novel anthranilic hydroxamate-based inhibitors of the prostaglandin H 2 synthase peroxidase activity J Lee, AJ Chubb, E Moman, BM McLoughlin, CT Sharkey, JG Kelly, ... Organic & Biomolecular Chemistry 3 (20), 3678-3685, 2005 | 19 | 2005 |
C‐reactive protein binds to αIIbβ3 MP Brennan, RD Moriarty, S Grennan, AJ Chubb, D Cox Journal of thrombosis and haemostasis 6 (7), 1239-1241, 2008 | 17 | 2008 |