Yusuf A Hannun
Yusuf A Hannun
Director, Stony Brook Cancer Center
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Zitiert von
Zitiert von
Principles of bioactive lipid signalling: lessons from sphingolipids
YA Hannun, LM Obeid
Nature reviews Molecular cell biology 9 (2), 139-150, 2008
Programmed cell death induced by ceramide
LM Obeid, CM Linardic, LA Karolak, YA Hannun
Science 259 (5102), 1769-1771, 1993
Functions of ceramide in coordinating cellular responses to stress
YA Hannun
Science 274 (5294), 1855-1859, 1996
The sphingomyelin cycle and the second messenger function of ceramide
YA Hannun
The Journal of biological chemistry 269 (5), 3125-3128, 1994
Functions of sphingolipids and sphingolipid breakdown products in cellular regulation
YA Hannun, RM Bell
Science 243 (4890), 500-507, 1989
Sphingolipids and their metabolism in physiology and disease
YA Hannun, LM Obeid
Nature reviews Molecular cell biology 19 (3), 175-191, 2018
Biologically active sphingolipids in cancer pathogenesis and treatment
B Ogretmen, YA Hannun
Nature Reviews Cancer 4 (8), 604-616, 2004
Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.
YA Hannun, CR Loomis, AH Merrill Jr, RM Bell
Journal of Biological Chemistry 261 (27), 12604-12609, 1986
An overview of sphingolipid metabolism: from synthesis to breakdown
CR Gault, LM Obeid, YA Hannun
Sphingolipids as signaling and regulatory molecules, 1-23, 2010
The ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind
YA Hannun, LM Obeid
Journal of Biological Chemistry 277 (29), 25847-25850, 2002
Ceramide in the eukaryotic stress response
YA Hannun, C Luberto
Trends in cell biology 10 (2), 73-80, 2000
Ceramide in apoptosis: an overview and current perspectives
BJ Pettus, CE Chalfant, YA Hannun
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2002
Apoptosis and the dilemma of cancer chemotherapy
YA Hannun
Blood, The Journal of the American Society of Hematology 89 (6), 1845-1853, 1997
The complex life of simple sphingolipids
AH Futerman, YA Hannun
EMBO reports 5 (8), 777-782, 2004
Sphingomyelin turnover induced by vitamin D3 in HL-60 cells: role in cell differentiation
T Okazaki, RM Bell, YA Hannun
Journal of Biological Chemistry 264 (32), 19076-19080, 1989
Bioactive sphingolipids: metabolism and function
N Bartke, YA Hannun
Journal of lipid research 50, S91-S96, 2009
Substantial contribution of extrinsic risk factors to cancer development
S Wu, S Powers, W Zhu, YA Hannun
Nature 529 (7584), 43-47, 2016
Ceramide activates heterotrimeric protein phosphatase 2A
RT Dobrowsky, C Kamibayashi, MC Mumby, YA Hannun
Journal of Biological Chemistry 268 (21), 15523-15530, 1993
Ceramide: an intracellular signal for apoptosis
YA Hannun, LM Obeid
Trends in biochemical sciences 20 (2), 73-77, 1995
Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation.
MY Kim, C Linardic, L Obeid, Y Hannun
Journal of Biological Chemistry 266 (1), 484-489, 1991
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