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Alaa Elwan
Alaa Elwan
Faculty of pharmacy - Al-Azhar university - Medicinal chemistry and drug design department
Verified email at azhar.edu.eg
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Cited by
Cited by
Year
New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies
H Elkady, A Elwan, HA El-Mahdy, AS Doghish, A Ismail, MS Taghour, ...
Journal of enzyme inhibition and medicinal chemistry 37 (1), 403-416, 2022
1022022
Discovery of thieno [2, 3-d] pyrimidine-based derivatives as potent VEGFR-2 kinase inhibitors and anti-cancer agents
SA El-Metwally, MM Abou-El-Regal, IH Eissa, ABM Mehany, HA Mahdy, ...
Bioorganic Chemistry 112, 104947, 2021
792021
Design, synthesis, docking, ADMET studies, and anticancer evaluation of new 3-methylquinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers
MM Alanazi, IH Eissa, NA Alsaif, AJ Obaidullah, WA Alanazi, AF Alasmari, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 1760-1782, 2021
692021
Design, synthesis, molecular docking and anti-proliferative evaluations of [1, 2, 4] triazolo [4, 3-a] quinoxaline derivatives as DNA intercalators and Topoisomerase II inhibitors
K El-Adl, AGA El-Helby, H Sakr, A Elwan
Bioorganic Chemistry 105, 104399, 2020
472020
Discovery of new VEGFR-2 inhibitors based on bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as anticancer agents and apoptosis inducers
NA Alsaif, MS Taghour, MM Alanazi, AJ Obaidullah, AA Al-Mehizia, ...
Journal of enzyme inhibition and medicinal chemistry 36 (1), 1093-1114, 2021
442021
A multistage in silico study of natural potential inhibitors targeting SARS-CoV-2 main protease
EB Elkaeed, IH Eissa, H Elkady, A Abdelalim, AM Alqaisi, AA Alsfouk, ...
International Journal of Molecular Sciences 23 (15), 8407, 2022
402022
Discovery of new 3-methylquinoxalines as potential anti-cancer agents and apoptosis inducers targeting VEGFR-2: design, synthesis, and in silico studies
MM Alanazi, A Elwan, NA Alsaif, AJ Obaidullah, HM Alkahtani, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 1732-1750, 2021
382021
[1, 2, 4] Triazolo [4, 3-a] quinoxaline and [1, 2, 4] triazolo [4, 3-a] quinoxaline-1-thiol-derived DNA intercalators: design, synthesis, molecular docking, in silico ADMET …
K El-Adl, AGA El-Helby, H Sakr, A Elwan
New journal of chemistry 45 (2), 881-897, 2021
352021
Design, molecular docking and synthesis of some novel 4-acetyl-1-substituted-3,4-dihydroquinoxalin-2(1H)-one derivatives for anticonvulsant evaluation as AMPA …
AGA El-Helby, RRA Ayyad, K El-Adl, H Sakr, AA Abd-Elrahman, IH Eissa, ...
Medicinal Chemistry Research 25, 3030-3046, 2016
342016
Modified benzoxazole-based VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, and anti-proliferative evaluation
A Elwan, AE Abdallah, HA Mahdy, MA Dahab, MS Taghour, EB Elkaeed, ...
Molecules 27 (15), 5047, 2022
282022
Quinoxalin-2(1H)-one derived AMPA-receptor antagonists: Design, synthesis, molecular docking and anticonvulsant activity
AGA El-Helby, RRA Ayyad, K El-Adl, A Elwan
Medicinal Chemistry Research 26, 2967-2984, 2017
282017
Benzoxazole derivatives as new VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, in silico studies, and antiproliferative evaluation
MS Taghour, HA Mahdy, MH Gomaa, A Aglan, MG Eldeib, A Elwan, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2063-2077, 2022
262022
Anti-cancer and immunomodulatory evaluation of new nicotinamide derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: in vitro and in silico studies
RG Yousef, A Elwan, IMM Gobaara, ABM Mehany, WM Eldehna, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 2206-2222, 2022
232022
Structure-based virtual screening, docking, ADMET, molecular dynamics, and MM-PBSA calculations for the discovery of potential natural SARS-CoV-2 helicase inhibitors from the …
AM Metwaly, A Elwan, AAMM El-Attar, ST Al-Rashood, IH Eissa
Journal of Chemistry 2022, 2022
132022
Targeting VEGFR‐2 by new quinoxaline derivatives: Design, synthesis, antiproliferative assay, apoptosis induction, and in silico studies
NA Alsaif, HA Mahdy, MM Alanazi, AJ Obaidullah, HM Alkahtani, ...
Archiv der Pharmazie 355 (2), 2100359, 2022
132022
Design, synthesis and molecular docking of new [1, 2, 4] triazolo [4, 3-a] quinoxaline derivatives as anticancer agents targeting VEGFR-2 kinase
NA Alsaif, A Elwan, MM Alanazi, AJ Obaidullah, WA Alanazi, AF Alasmari, ...
Molecular Diversity 26 (4), 1915-1932, 2022
122022
Design, synthesis, in silico and in vitro studies of new immunomodulatory anticancer nicotinamide derivatives targeting VEGFR-2
RG Yousef, WM Eldehna, A Elwan, AS Abdelaziz, ABM Mehany, ...
Molecules 27 (13), 4079, 2022
112022
Design, synthesis, molecular modeling and biological evaluation of novel Benzoxazole-Benzamide conjugates via a 2-Thioacetamido linker as potential anti …
IH Eissa, R El-Haggar, MA Dahab, MF Ahmed, HA Mahdy, RI Alsantali, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1587-1599, 2022
102022
New theobromine derivatives inhibiting VEGFR-2: design, synthesis, antiproliferative, docking and molecular dynamics simulations
HA Mahdy, H Elkady, MS Taghour, A Elwan, MA Dahab, MA Elkady, ...
Future Medicinal Chemistry 15 (14), 1233-1250, 2023
72023
New [1,2,4]triazolo[4,3‐c]quinazoline derivatives as vascular endothelial growth factor receptor‐2 inhibitors and apoptosis inducers: Design, synthesis, docking …
AE Azab, MS Alesawy, WM Eldehna, A Elwan, IH Eissa
Archiv der Pharmazie 355 (10), 2200133, 2022
72022
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