Therapeutically exploiting STAT3 activity in cancer—using tissue repair as a road map J Huynh, A Chand, D Gough, M Ernst Nature Reviews Cancer 19 (2), 82-96, 2019 | 431 | 2019 |
The JAK/STAT3 axis: A comprehensive drug target for solid malignancies J Huynh, N Etemadi, F Hollande, M Ernst, M Buchert Seminars in cancer biology 45, 13-22, 2017 | 169 | 2017 |
ADAM17 is required for EGF-R–induced intestinal tumors via IL-6 trans-signaling S Schmidt, N Schumacher, J Schwarz, S Tangermann, L Kenner, ... Journal of Experimental Medicine 215 (4), 1205-1225, 2018 | 68 | 2018 |
Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiation MQ Kwa, J Huynh, J Aw, L Zhang, T Nguyen, EC Reynolds, MJ Sweet, ... Journal of Biological Chemistry 289 (45), 31077-31087, 2014 | 62 | 2014 |
IRF6 regulates the expression of IL-36γ by human oral epithelial cells in response to porphyromonas gingivalis J Huynh, GM Scholz, J Aw, MQ Kwa, A Achuthan, JA Hamilton, ... The Journal of Immunology 196 (5), 2230-2238, 2016 | 57 | 2016 |
CSF-1 receptor signalling from endosomes mediates the sustained activation of Erk1/2 and Akt in macrophages J Huynh, MQ Kwa, AD Cook, JA Hamilton, GM Scholz Cellular signalling 24 (9), 1753-1761, 2012 | 46 | 2012 |
Interferon regulatory factor 6 differentially regulates Toll-like receptor 2-dependent chemokine gene expression in epithelial cells MQ Kwa, T Nguyen, J Huynh, D Ramnath, D De Nardo, PY Lam, ... Journal of Biological Chemistry 289 (28), 19758-19768, 2014 | 42 | 2014 |
Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth P Thilakasiri, J Huynh, AR Poh, CW Tan, TL Nero, K Tran, AC Parslow, ... EMBO molecular medicine 11 (4), e9539, 2019 | 39 | 2019 |
Host IL11 Signaling Suppresses CD4+ T cell–Mediated Antitumor Responses to Colon Cancer in Mice J Huynh, D Baloyan, D Chisanga, W Shi, M O'Brien, S Afshar-Sterle, ... Cancer immunology research 9 (7), 735-747, 2021 | 24 | 2021 |
Disease-associated mutations in IRF6 and RIPK4 dysregulate their signalling functions MQ Kwa, J Huynh, EC Reynolds, JA Hamilton, GM Scholz Cellular Signalling 27 (7), 1509-1516, 2015 | 22 | 2015 |
Hypoxia enhances the proliferative response of macrophages to CSF-1 and their pro-survival response to TNF JA Hamilton, DC Lacey, A Turner, B De Kok, J Huynh, GM Scholz Public Library of Science 7 (9), e45853, 2012 | 15 | 2012 |
STAT3 signalling via the IL-6ST/gp130 cytokine receptor promotes epithelial integrity and intestinal barrier function during DSS-induced colitis L Pang, J Huynh, MG Alorro, X Li, M Ernst, AL Chand Biomedicines 9 (2), 187, 2021 | 13 | 2021 |
Exploiting the STAT3 nexus in cancer-associated fibroblasts to improve cancer therapy A Allam, M Yakou, L Pang, M Ernst, J Huynh Frontiers in immunology 12, 767939, 2021 | 12 | 2021 |
IL-36G promotes cancer-cell intrinsic hallmarks in human gastric cancer cells N Le, I Luk, D Chisanga, W Shi, L Pang, G Scholz, J Mariadason, M Ernst, ... Cytokine 155, 155887, 2022 | 8 | 2022 |
Interplay between Porphyromonas gingivalis and EGF signalling in the regulation of CXCL14 J Aw, GM Scholz, NL Huq, J Huynh, NM O'Brien‐Simpson, EC Reynolds Cellular microbiology 20 (7), e12837, 2018 | 8 | 2018 |
Interferon regulatory factor 6 promotes keratinocyte differentiation in response to Porphyromonas gingivalis J Huynh, GM Scholz, J Aw, EC Reynolds Infection and Immunity 85 (5), 10.1128/iai. 00858-16, 2017 | 8 | 2017 |
Development of a multiplex immunohistochemistry workflow to investigate the immune microenvironment in mouse models of inflammatory bowel disease and colon cancer L Pang, M Ernst, J Huynh International journal of molecular sciences 22 (20), 11001, 2021 | 3 | 2021 |
Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss JO Mejía-Hernández, SP Keam, R Saleh, F Muntz, SB Fox, D Byrne, ... Cell Death & Disease 13 (9), 777, 2022 | 2 | 2022 |
IL6 signaling in cancer: Not always bad news J Huynh, M Ernst Cancer research 81 (18), 4671-4672, 2021 | 2 | 2021 |
Protocol for investigating tertiary lymphoid structures in human and murine fixed tissue sections using Opal™-TSA multiplex immunohistochemistry LT Quigley, L Pang, E Tavancheh, M Ernst, A Behren, J Huynh, ... STAR protocols 4 (1), 101961, 2023 | 1 | 2023 |