| Impact of Dynamically Exposed Polarity on Permeability and Solubility of Chameleonic Drugs Beyond the Rule of 5 MR Sebastiano, BC Doak, M Backlund, V Poongavanam, B Over, ... Journal of Medicinal Chemistry 61 (9), 4189–4202, 2018 | 201 | 2018 |
| Overview of recent strategic advances in medicinal chemistry G Wu, T Zhao, D Kang, J Zhang, Y Song, V Namasivayam, J Kongsted, ... Journal of medicinal chemistry 62 (21), 9375-9414, 2019 | 147 | 2019 |
| Solution Conformations Shed Light on PROTAC Cell Permeability Y Atilaw, Y Poongavanam, CS Nilsson, D Nguyen, A Giese, D Meibom, ... ACS Med. Chem. Lett. 12 (1), 107–114, 2020 | 128 | 2020 |
| Classification of cytochrome P450 1A2 inhibitors and noninhibitors by machine learning techniques P Vasanthanathan, O Taboureau, C Oostenbrink, NPE Vermeulen, ... Drug Metabolism and Disposition 37 (3), 658-664, 2009 | 122 | 2009 |
| Ligand and structure-based classification models for prediction of P-glycoprotein inhibitors F Klepsch, P Vasanthanathan, GF Ecker Journal of chemical information and modeling 54 (1), 218-229, 2014 | 117 | 2014 |
| Synthesis, analgesic and anti-inflammatory activities of some novel 2, 3-disubstituted quinazolin-4 (3H)-ones V Alagarsamy, V Muthukumar, N Pavalarani, P Vasanthanathan, ... Biological and Pharmaceutical Bulletin 26 (4), 557-559, 2003 | 117 | 2003 |
| Macrocycles in Drug Discovery─Learning from the Past for the Future DG Jimenez, V Poongavanam, J Kihlberg Journal of Medicinal Chemistry 66 (8), 5377–5396, 2023 | 110 | 2023 |
| Enhancing preclinical drug discovery with artificial intelligence RSK Vijayan, J Kihlberg, JB Cross, V Poongavanam Drug Discovery Today 27 (4), 967-984, 2021 | 107 | 2021 |
| Solution conformations explain the chameleonic behaviour of macrocyclic drugs E Danelius, V Poongavanam, S Peintner, L Wieske, M Erdelyi, J Kihlberg Chemistry–A European Journal, 2020 | 104 | 2020 |
| Fingerprint-based in silico models for the prediction of P-glycoprotein substrates and inhibitors V Poongavanam, N Haider, GF Ecker Bioorganic & medicinal chemistry 20 (18), 5388-5395, 2012 | 91 | 2012 |
| Virtual screening and prediction of site of metabolism for cytochrome P450 1A2 ligands P Vasanthanathan, J Hritz, O Taboureau, L Olsen, F Steen Jørgensen, ... Journal of chemical information and modeling 49 (1), 43-52, 2009 | 89 | 2009 |
| Conformational Sampling of Macrocyclic Drugs in Different Environments: Can We Find the Relevant Conformations? V Poongavanam, E Danelius, L , Peintner,S, Alcaraz, G Caron, ... ACS Omega 3, 11742−11757, 2018 | 88 | 2018 |
| Opportunities and guidelines for discovery of orally absorbed drugs in beyond rule of 5 space V Poongavanam, BC Doak, J Kihlberg Current Opinion in Chemical Biology 44, 23-29, 2018 | 87 | 2018 |
| Recent developments in the medicinal chemistry of single boron atom-containing compounds S Song, P Gao, L Sun, D Kang, J Kongsted, V Poongavanam, P Zhan, ... Acta Pharmaceutica Sinica B 11 (10), 3035-3059, 2021 | 86 | 2021 |
| Viral M2 Ion Channel Protein: A Promising Target for Anti-influenza Drug Discovery NSHN Moorthy, V Poongavanam, P V Mini-Reviews in Medicinal Chemistry 14 (10), 819-830, 2014 | 79 | 2014 |
| Linker-Dependent Folding Rationalizes PROTAC Cell Permeability V Poongavanam, Y Atilaw, S Siegel, A Giese, L , Lehmann, D Meibom, ... Journal of Medicinal Chemistry 65 (19), 13029–13040, 2022 | 73 | 2022 |
| Design, synthesis and biological evaluation of tacrine-1, 2, 3-triazole derivatives as potent cholinesterase inhibitors G Wu, Y Gao, D Kang, B Huang, Z Huo, H Liu, V Poongavanam, P Zhan, ... MedChemCommun 9, 149-159, 2018 | 67 | 2018 |
| Steering New Drug Discovery Campaigns: Permeability, Solubility, and Physicochemical Properties in the bRo5 Chemical Space G Caron, J Kihlberg, G Goetz, E Ratkova, V Poongavanam, G Ermondi ACS Medicinal Chemistry Letters 12 (1), 13-23, 2021 | 61 | 2021 |
| Optimization of N-substituted oseltamivir derivatives as potent inhibitors of group-1 and-2 influenza A neuraminidases, including a drug-resistant variant J Zhang, V Poongavanam, D Kang, C Bertagnin, H Lu, X Kong, H Ju, X Lu, ... Journal of medicinal chemistry 61 (14), 6379-6397, 2018 | 57 | 2018 |
| Fast prediction of cytochrome P450 mediated drug metabolism P Rydberg, P Vasanthanathan, C Oostenbrink, L Olsen ChemMedChem 4 (12), 2070-2079, 2009 | 57 | 2009 |
Jacob KongstedUniverity of Southern DenmarkBestätigte E-Mail-Adresse bei sdu.dk
