| Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and-independent mechanisms LI Grad, JJ Yerbury, BJ Turner, WC Guest, E Pokrishevsky, MA O’Neill, ... Proceedings of the National Academy of Sciences 111 (9), 3620-3625, 2014 | 447 | 2014 |
| Intermolecular transmission of superoxide dismutase 1 misfolding in living cells LI Grad, WC Guest, A Yanai, E Pokrishevsky, MA O'Neill, E Gibbs, ... Proceedings of the National Academy of Sciences 108 (39), 16398-16403, 2011 | 301 | 2011 |
| Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis E Pokrishevsky, LI Grad, M Yousefi, J Wang, IR Mackenzie, NR Cashman PloS one 7 (4), e35050, 2012 | 219 | 2012 |
| TDP-43 or FUS-induced misfolded human wild-type SOD1 can propagate intercellularly in a prion-like fashion E Pokrishevsky, LI Grad, NR Cashman Scientific reports 6 (1), 22155, 2016 | 83 | 2016 |
| Generalization of the prion hypothesis to other neurodegenerative diseases: an imperfect fit WC Guest, JM Silverman, E Pokrishevsky, MA O'Neill, LI Grad, ... Journal of Toxicology and Environmental Health, Part A 74 (22-24), 1433-1459, 2011 | 75 | 2011 |
| Exosome-dependent and independent mechanisms are involved in prion-like transmission of propagated Cu/Zn superoxide dismutase misfolding LI Grad, E Pokrishevsky, JM Silverman, NR Cashman Prion 8 (5), 331-335, 2014 | 69 | 2014 |
| Tryptophan 32-mediated SOD1 aggregation is attenuated by pyrimidine-like compounds in living cells E Pokrishevsky, L McAlary, NE Farrawell, B Zhao, M Sher, JJ Yerbury, ... Scientific Reports 8 (1), 15590, 2018 | 42 | 2018 |
| Spinal cord homogenates from SOD1 familial amyotrophic lateral sclerosis induce SOD1 aggregation in living cells E Pokrishevsky, RH Hong, IR Mackenzie, NR Cashman PloS one 12 (9), e0184384, 2017 | 33 | 2017 |
| Tryptophan 32 mediates SOD1 toxicity in a in vivo motor neuron model of ALS and is a promising target for small molecule therapeutics MG DuVal, VK Hinge, N Snyder, R Kanyo, J Bratvold, E Pokrishevsky, ... Neurobiology of disease 124, 297-310, 2019 | 25 | 2019 |
| Intercellular prion-like conversion and transmission of Cu/Zn superoxide dismutase (SOD1) in cell culture LI Grad, E Pokrishevsky, NR Cashman Prions: Methods and Protocols, 357-367, 2017 | 8 | 2017 |
| Misfolded wild-type SOD1 induced by pathological FUS or TDP-43 transmits intercellularly and is propagation-competent E Pokrishevsky, L Grad, N Cashman Prion 9, S7-S8, 2015 | 2 | 2015 |
| Tryptophan residues in TDP-43 and SOD1 modulate the cross-seeding and toxicity of SOD1 E Pokrishevsky, MG DuVal, L McAlary, S Louadi, S Pozzi, A Roman, ... Journal of Biological Chemistry, 107207, 2024 | 1 | 2024 |
| P4‐163: THE PATHOLOGICAL INTERACTOME OF TDP‐43 INCLUDES HUMAN WILDTYPE SOD1 E Pokrishevsky, M DuVal, L McAlary, B Zhao, E Gibbs, S Louadi, J Kaplan, ... Alzheimer's & Dementia 15, P1336-P1337, 2019 | | 2019 |
| TDP-43 induces SOD1 aggregation and toxicity via tryptophan interactions that present a novel drug target MG DuVal, E Pokrishevsky, VK Hinge, J Bratvold, R Kanyo, N Snyder, ... PRION 13, 110-111, 2019 | | 2019 |
| Induction of Cu/Zn Superoxide Dismutase (SOD1) Aggregation in Living Cells E Pokrishevsky, J Nan, NR Cashman Protein Misfolding Diseases: Methods and Protocols, 213-224, 2019 | | 2019 |
| Induction of wild-type SOD1 misfolding, aggregation and its cell-to-cell propagation E Pokrishevsky University of British Columbia, 2017 | | 2017 |
| Aberrant localization of fused in sarcoma (FUS) and TAR DNA binding protein (TDP)-43 triggers misfolding of human Cu/Zn superoxide dismutase (SOD1) E Pokrishevsky University of British Columbia, 2011 | | 2011 |
| Aberrant localization of fused in sarcoma (FUS) and TAR DNA binding protein (TDP)-43 triggers misfolding of human Cu/Zn superoxide dismutase (SOD1) E Pokrishevsky University of British Columbia, 2011 | | 2011 |
| Prion-Like Propagation of SOD1 Misfolding In Vitro NR Cashman, LI Grad, A Yanai, W Guest, MA O'Neill, E Pokrishevsky, ... NEUROLOGY 74 (9), A503-A503, 2010 | | 2010 |
| PRION-LIKE MECHANISMS IN AMYOTROPHIC LATERAL SCLEROSIS LI Grad, E Pokrishevsky, NR Cashman | | |
