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Zhipeng Hou
Zhipeng Hou
Computer Imaging
Bestätigte E-Mail-Adresse bei jh.edu
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Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets
M Jiang, J Wang, J Fu, L Du, H Jeong, T West, L Xiang, Q Peng, Z Hou, ...
Nature medicine 18 (1), 153-158, 2012
3632012
Mutant huntingtin N-terminal fragments of specific size mediate aggregation and toxicity in neuronal cells
T Ratovitski, M Gucek, H Jiang, E Chighladze, E Waldron, J D'Ambola, ...
Journal of biological chemistry 284 (16), 10855-10867, 2009
1602009
Small-molecule TrkB receptor agonists improve motor function and extend survival in a mouse model of Huntington's disease
M Jiang, Q Peng, X Liu, J Jin, Z Hou, J Zhang, S Mori, CA Ross, K Ye, ...
Human molecular genetics 22 (12), 2462-2470, 2013
1342013
Photoactivated composite biomaterial for soft tissue restoration in rodents and in humans
AT Hillel, S Unterman, Z Nahas, B Reid, JM Coburn, J Axelman, JJ Chae, ...
Science translational medicine 3 (93), 93ra67-93ra67, 2011
1232011
Longitudinal characterization of brain atrophy of a Huntington's disease mouse model by automated morphological analyses of magnetic resonance images
J Zhang, Q Peng, Q Li, N Jahanshad, Z Hou, M Jiang, N Masuda, ...
Neuroimage 49 (3), 2340-2351, 2010
1102010
Cognitive impairments induced by necrotizing enterocolitis can be prevented by inhibiting microglial activation in mouse brain
DF Niño, Q Zhou, Y Yamaguchi, LY Martin, S Wang, WB Fulton, H Jia, ...
Science translational medicine 10 (471), eaan0237, 2018
1062018
Resource atlases for multi-atlas brain segmentations with multiple ontology levels based on T1-weighted MRI
D Wu, T Ma, C Ceritoglu, Y Li, J Chotiyanonta, Z Hou, J Hsu, X Xu, ...
Neuroimage 125, 120-130, 2016
992016
Fibril polymorphism affects immobilized non-amyloid flanking domains of huntingtin exon1 rather than its polyglutamine core
HK Lin, JC Boatz, IE Krabbendam, R Kodali, Z Hou, R Wetzel, AM Dolga, ...
Nature communications 8 (1), 15462, 2017
932017
Polyglutamine amyloid core boundaries and flanking domain dynamics in huntingtin fragment fibrils determined by solid-state nuclear magnetic resonance
CL Hoop, HK Lin, K Kar, Z Hou, MA Poirier, R Wetzel, PCA Van Der Wel
Biochemistry 53 (42), 6653-6666, 2014
912014
Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease
J Jin, Q Peng, Z Hou, M Jiang, X Wang, AJ Langseth, M Tao, PB Barker, ...
Human molecular genetics 24 (9), 2508-2527, 2015
852015
Multimodality MRI assessment of grey and white matter injury and blood-brain barrier disruption after intracerebral haemorrhage in mice
J Yang, Q Li, Z Wang, C Qi, X Han, X Lan, J Wan, W Wang, X Zhao, Z Hou, ...
Scientific reports 7 (1), 40358, 2017
812017
Toxic role of prostaglandin E2 receptor EP1 after intracerebral hemorrhage in mice
X Zhao, T Wu, CF Chang, H Wu, X Han, Q Li, Y Gao, Q Li, Z Hou, ...
Brain, behavior, and immunity 46, 293-310, 2015
802015
Characterization of behavioral, neuropathological, brain metabolic and key molecular changes in zQ175 knock-in mouse model of Huntington’s disease
Q Peng, B Wu, M Jiang, J Jin, Z Hou, J Zheng, J Zhang, W Duan
PloS one 11 (2), e0148839, 2016
642016
Transgenic mouse model expressing the caspase 6 fragment of mutant huntingtin
E Waldron-Roby, T Ratovitski, XF Wang, M Jiang, E Watkin, N Arbez, ...
Journal of Neuroscience 32 (1), 183-193, 2012
622012
Structural MRI detects progressive regional brain atrophy and neuroprotective effects in N171-82Q Huntington's disease mouse model
Y Cheng, Q Peng, Z Hou, M Aggarwal, J Zhang, S Mori, CA Ross, W Duan
Neuroimage 56 (3), 1027-1034, 2011
622011
Sirtuin 1 activator SRT 2104 protects Huntington's disease mice
M Jiang, J Zheng, Q Peng, Z Hou, J Zhang, S Mori, JL Ellis, GP Vlasuk, ...
Annals of clinical and translational neurology 1 (12), 1047-1052, 2014
512014
Diffeomorphic registration with intensity transformation and missing data: Application to 3D digital pathology of Alzheimer's disease
D Tward, T Brown, Y Kageyama, J Patel, Z Hou, S Mori, M Albert, ...
Frontiers in neuroscience 14, 478330, 2020
482020
Small molecule modulator of protein disulfide isomerase attenuates mutant huntingtin toxicity and inhibits endoplasmic reticulum stress in a mouse model of Huntington’s disease
X Zhou, G Li, A Kaplan, MM Gaschler, X Zhang, Z Hou, M Jiang, R Zott, ...
Human molecular genetics 27 (9), 1545-1555, 2018
472018
2, 4 DNP improves motor function, preserves medium spiny neuronal identity, and reduces oxidative stress in a mouse model of Huntington's disease
B Wu, M Jiang, Q Peng, G Li, Z Hou, GL Milne, S Mori, R Alonso, ...
Experimental Neurology 293, 83-90, 2017
442017
Maternal pravastatin prevents altered fetal brain development in a preeclamptic CD-1 mouse model
AR Carver, M Andrikopoulou, J Lei, E Tamayo, P Gamble, Z Hou, J Zhang, ...
PloS one 9 (6), e100873, 2014
392014
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