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Alexandra Ortiz (O'Sick)
Alexandra Ortiz (O'Sick)
Verified email at nih.gov
Title
Cited by
Cited by
Year
Microbiota-dependent sequelae of acute infection compromise tissue-specific immunity
DM Da Fonseca, TW Hand, SJ Han, MY Gerner, AG Zaretsky, AL Byrd, ...
Cell 163 (2), 354-366, 2015
2652015
Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection
NR Klatt, JD Estes, X Sun, AM Ortiz, JS Barber, LD Harris, B Cervasi, ...
Mucosal immunology 5 (6), 646-657, 2012
2412012
Low levels of SIV infection in sooty mangabey central memory CD4+ T cells are associated with limited CCR5 expression
M Paiardini, B Cervasi, E Reyes-Aviles, L Micci, AM Ortiz, A Chahroudi, ...
Nature medicine 17 (7), 830-836, 2011
2182011
Dysbiotic bacteria translocate in progressive SIV infection
Z Klase, A Ortiz, C Deleage, JC Mudd, M Quiñones, E Schwartzman, ...
Mucosal immunology 8 (5), 1009-1020, 2015
1442015
Depletion of CD4+ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques
AM Ortiz, NR Klatt, B Li, Y Yi, B Tabb, XP Hao, L Sternberg, B Lawson, ...
The Journal of clinical investigation 121 (11), 2011
1342011
Tissue myeloid cells in SIV-infected primates acquire viral DNA through phagocytosis of infected T cells
N Calantone, F Wu, Z Klase, C Deleage, M Perkins, K Matsuda, ...
Immunity 41 (3), 493-502, 2014
1252014
CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells
L Micci, X Alvarez, RI Iriele, AM Ortiz, ES Ryan, CS McGary, C Deleage, ...
PLoS pathogens 10 (10), e1004467, 2014
1212014
Gut-resident Lactobacillus abundance associates with IDO1 inhibition and Th17 dynamics in SIV-infected macaques
I Vujkovic-Cvijin, LA Swainson, SN Chu, AM Ortiz, CA Santee, A Petriello, ...
Cell reports 13 (8), 1589-1597, 2015
972015
IL-21 and probiotic therapy improve Th17 frequencies, microbial translocation, and microbiome in ARV-treated, SIV-infected macaques
AM Ortiz, ZA Klase, SR DiNapoli, I Vujkovic-Cvijin, K Carmack, ...
Mucosal immunology 9 (2), 458-467, 2016
942016
Tissue-resident macrophages can contain replication-competent virus in antiretroviral-naive, SIV-infected Asian macaques
SR DiNapoli, AM Ortiz, F Wu, K Matsuda, HL Twigg III, VM Hirsch, K Knox, ...
JCI insight 2 (4), 2017
692017
T-cell phenotypic and functional changes associated with social subordination and gene polymorphisms in the serotonin reuptake transporter in female rhesus monkeys
M Paiardini, J Hoffman, B Cervasi, AM Ortiz, F Stroud, G Silvestri, ...
Brain, behavior, and immunity 23 (2), 286-293, 2009
442009
Experimental microbial dysbiosis does not promote disease progression in SIV-infected macaques
AM Ortiz, JK Flynn, SR DiNapoli, I Vujkovic-Cvijin, CE Starke, SH Lai, ...
Nature medicine 24 (9), 1313-1316, 2018
362018
Multifunctional double-negative T cells in sooty mangabeys mediate T-helper functions irrespective of SIV infection
V Sundaravaradan, R Saleem, L Micci, MA Gasper, AM Ortiz, J Else, ...
PLoS pathogens 9 (6), e1003441, 2013
352013
Macrophages are phenotypically and functionally diverse across tissues in simian immunodeficiency virus-infected and uninfected Asian macaques
AM Ortiz, SR DiNapoli, JM Brenchley
Journal of Virology 89 (11), 5883-5894, 2015
282015
Limited CD4+ T cell proliferation leads to preservation of CD4+ T cell counts in SIV-infected sooty mangabeys
ML Chan, J Petravic, AM Ortiz, J Engram, M Paiardini, D Cromer, ...
Proceedings of the Royal Society B: Biological Sciences 277 (1701), 3773-3781, 2010
272010
Impact of acute HIV infection and early antiretroviral therapy on the human gut microbiome
O Sortino, N Phanuphak, A Schuetz, AM Ortiz, N Chomchey, Y Belkaid, ...
Open Forum Infectious Diseases 7 (12), ofz367, 2020
182020
Loss of mucosal CD103 DCs and IL-17 and IL-22 lymphocytes is associated with mucosal damage in SIV infection. Mucosal Immunol 5: 646–657
NR Klatt, JD Estes, X Sun, AM Ortiz, JS Barber, LD Harris, B Cervasi, ...
172012
The Vaginal Microbiome of Nonhuman Primates Can Be Only Transiently Altered to Become Lactobacillus Dominant without Reducing Inflammation
CA Langner, AM Ortiz, JK Flynn, H Kendall, LA Lagenaur, JM Brenchley
Microbiology Spectrum 9 (3), e01074-21, 2021
162021
Microbial translocation: translating simian immunodeficiency virus to HIV
AM Ortiz, JM Brenchley
Current Opinion in HIV and AIDS 13 (1), 15-21, 2018
162018
Antiretroviral therapy administration in healthy rhesus macaques is associated with transient shifts in intestinal bacterial diversity and modest immunological perturbations
AM Ortiz, JK Flynn, SR DiNapoli, O Sortino, I Vujkovic-Cvijin, Y Belkaid, ...
Journal of Virology 93 (18), 10.1128/jvi. 00472-19, 2019
152019
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