Microbiota-dependent sequelae of acute infection compromise tissue-specific immunity DM Da Fonseca, TW Hand, SJ Han, MY Gerner, AG Zaretsky, AL Byrd, ... Cell 163 (2), 354-366, 2015 | 265 | 2015 |
Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection NR Klatt, JD Estes, X Sun, AM Ortiz, JS Barber, LD Harris, B Cervasi, ... Mucosal immunology 5 (6), 646-657, 2012 | 241 | 2012 |
Low levels of SIV infection in sooty mangabey central memory CD4+ T cells are associated with limited CCR5 expression M Paiardini, B Cervasi, E Reyes-Aviles, L Micci, AM Ortiz, A Chahroudi, ... Nature medicine 17 (7), 830-836, 2011 | 218 | 2011 |
Dysbiotic bacteria translocate in progressive SIV infection Z Klase, A Ortiz, C Deleage, JC Mudd, M Quiñones, E Schwartzman, ... Mucosal immunology 8 (5), 1009-1020, 2015 | 144 | 2015 |
Depletion of CD4+ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques AM Ortiz, NR Klatt, B Li, Y Yi, B Tabb, XP Hao, L Sternberg, B Lawson, ... The Journal of clinical investigation 121 (11), 2011 | 134 | 2011 |
Tissue myeloid cells in SIV-infected primates acquire viral DNA through phagocytosis of infected T cells N Calantone, F Wu, Z Klase, C Deleage, M Perkins, K Matsuda, ... Immunity 41 (3), 493-502, 2014 | 125 | 2014 |
CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells L Micci, X Alvarez, RI Iriele, AM Ortiz, ES Ryan, CS McGary, C Deleage, ... PLoS pathogens 10 (10), e1004467, 2014 | 121 | 2014 |
Gut-resident Lactobacillus abundance associates with IDO1 inhibition and Th17 dynamics in SIV-infected macaques I Vujkovic-Cvijin, LA Swainson, SN Chu, AM Ortiz, CA Santee, A Petriello, ... Cell reports 13 (8), 1589-1597, 2015 | 97 | 2015 |
IL-21 and probiotic therapy improve Th17 frequencies, microbial translocation, and microbiome in ARV-treated, SIV-infected macaques AM Ortiz, ZA Klase, SR DiNapoli, I Vujkovic-Cvijin, K Carmack, ... Mucosal immunology 9 (2), 458-467, 2016 | 94 | 2016 |
Tissue-resident macrophages can contain replication-competent virus in antiretroviral-naive, SIV-infected Asian macaques SR DiNapoli, AM Ortiz, F Wu, K Matsuda, HL Twigg III, VM Hirsch, K Knox, ... JCI insight 2 (4), 2017 | 69 | 2017 |
T-cell phenotypic and functional changes associated with social subordination and gene polymorphisms in the serotonin reuptake transporter in female rhesus monkeys M Paiardini, J Hoffman, B Cervasi, AM Ortiz, F Stroud, G Silvestri, ... Brain, behavior, and immunity 23 (2), 286-293, 2009 | 44 | 2009 |
Experimental microbial dysbiosis does not promote disease progression in SIV-infected macaques AM Ortiz, JK Flynn, SR DiNapoli, I Vujkovic-Cvijin, CE Starke, SH Lai, ... Nature medicine 24 (9), 1313-1316, 2018 | 36 | 2018 |
Multifunctional double-negative T cells in sooty mangabeys mediate T-helper functions irrespective of SIV infection V Sundaravaradan, R Saleem, L Micci, MA Gasper, AM Ortiz, J Else, ... PLoS pathogens 9 (6), e1003441, 2013 | 35 | 2013 |
Macrophages are phenotypically and functionally diverse across tissues in simian immunodeficiency virus-infected and uninfected Asian macaques AM Ortiz, SR DiNapoli, JM Brenchley Journal of Virology 89 (11), 5883-5894, 2015 | 28 | 2015 |
Limited CD4+ T cell proliferation leads to preservation of CD4+ T cell counts in SIV-infected sooty mangabeys ML Chan, J Petravic, AM Ortiz, J Engram, M Paiardini, D Cromer, ... Proceedings of the Royal Society B: Biological Sciences 277 (1701), 3773-3781, 2010 | 27 | 2010 |
Impact of acute HIV infection and early antiretroviral therapy on the human gut microbiome O Sortino, N Phanuphak, A Schuetz, AM Ortiz, N Chomchey, Y Belkaid, ... Open Forum Infectious Diseases 7 (12), ofz367, 2020 | 18 | 2020 |
Loss of mucosal CD103 DCs and IL-17 and IL-22 lymphocytes is associated with mucosal damage in SIV infection. Mucosal Immunol 5: 646–657 NR Klatt, JD Estes, X Sun, AM Ortiz, JS Barber, LD Harris, B Cervasi, ... | 17 | 2012 |
The Vaginal Microbiome of Nonhuman Primates Can Be Only Transiently Altered to Become Lactobacillus Dominant without Reducing Inflammation CA Langner, AM Ortiz, JK Flynn, H Kendall, LA Lagenaur, JM Brenchley Microbiology Spectrum 9 (3), e01074-21, 2021 | 16 | 2021 |
Microbial translocation: translating simian immunodeficiency virus to HIV AM Ortiz, JM Brenchley Current Opinion in HIV and AIDS 13 (1), 15-21, 2018 | 16 | 2018 |
Antiretroviral therapy administration in healthy rhesus macaques is associated with transient shifts in intestinal bacterial diversity and modest immunological perturbations AM Ortiz, JK Flynn, SR DiNapoli, O Sortino, I Vujkovic-Cvijin, Y Belkaid, ... Journal of Virology 93 (18), 10.1128/jvi. 00472-19, 2019 | 15 | 2019 |