Jie Xu

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ardem patapoutianThe Scripps Research Institute, Howard Hughes Medical InstituteVerified email at scripps.edu
Bertrand costeCNRS MarseilleVerified email at univ-amu.fr
David C TullyInterline TherapeuticsVerified email at interlinetx.com
Fuli XiangSun Ye-sun UniversityVerified email at mail.sysu.edu.cn
Zhaozhu Qiu (邱照铸)Johns Hopkins UniversityVerified email at jhmi.edu
Sanjeev S RanadePostdoctoral Fellow, UCSFVerified email at gladstone.ucsf.edu
Sung Sik HurResearch Professor, Soonchunhyang UniversityVerified email at sch.ac.kr
Yi-Shuan LiUniversity of California, San diegoVerified email at ucsd.edu
Ruhma SyedaResearch Associate, The Scripps Research InstituteVerified email at scripps.edu
Shang MaThe Scripps Research InstituteVerified email at scripps.edu
Daniel HenrionDirecteur de Recherche à l'INSERM et directeur du laboratoire MITOVASC (INSERM U1083 - CNRS UMR6214Verified email at univ-angers.fr
Anthony P OrthGNF - NIFG - NovartisVerified email at gnf.org
Viktor LukacsUniversity of LeedsVerified email at leeds.ac.uk
QI WUBaylor College of MedicineVerified email at bcm.edu
Young-Il Kim, MDCenter for Gastric Cancer, National Cancer Center, KoreaVerified email at ncc.re.kr
Bin FangNovartis Institutes for BioMedical ResearchVerified email at novartis.com
lloyd klicksteinCSO, Versanis BioVerified email at versanisbio.com
William DietrichWhitehead Institute, MIT, Harvard Medical School, NovartisVerified email at alum.mit.edu
Reginald ValdezAmgenVerified email at amgen.com
Andrew SornborgerResearch Scientist, Information Sciences CCS-3, Los Alamos National LaboratoryVerified email at lanl.gov

Jie Xu

Sun Yat-sen University

Verified email at mail.sysu.edu.cn

Mechanotransduction Cardiovascular Diseases Ion channels GPCR signaling Drug Discovery


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Piezo1, a mechanically activated ion channel, is required for vascular development in mice SS Ranade, Z Qiu, SH Woo, SS Hur, SE Murthy, SM Cahalan, J Xu, ... Proceedings of the National Academy of Sciences 111 (28), 10347-10352, 2014	810	2014
Chemical activation of the mechanotransduction channel Piezo1 R Syeda, J Xu, AE Dubin, B Coste, J Mathur, T Huynh, J Matzen, J Lao, ... elife 4, e07369, 2015	567	2015
Regulation of hunger-driven behaviors by neural ribosomal S6 kinase in Drosophila Q Wu, Y Zhang, J Xu, P Shen Proceedings of the National Academy of Sciences 102 (37), 13289-13294, 2005	284	2005
GPR68 senses flow and is essential for vascular physiology J Xu, J Mathur, E Vessières, S Hammack, K Nonomura, J Favre, ... Cell 173 (3), 762-775. e16, 2018	245	2018
Tropifexor‐mediated abrogation of steatohepatitis and fibrosis is associated with the antioxidative gene expression profile in rodents ED Hernandez, L Zheng, Y Kim, B Fang, B Liu, RA Valdez, WF Dietrich, ... Hepatology communications 3 (8), 1085-1097, 2019	83	2019
Drosophila TRPA channel modulates sugar-stimulated neural excitation, avoidance and social response J Xu, AT Sornborger, JK Lee, P Shen Nature neuroscience 11 (6), 676-682, 2008	70	2008
A G-protein-coupled neuropeptide Y-like receptor suppresses behavioral and sensory response to multiple stressful stimuli in Drosophila J Xu, M Li, P Shen Journal of Neuroscience 30 (7), 2504-2512, 2010	60	2010
LJN452 (tropifexor) attenuates steatohepatitis, inflammation, and fibrosis in dietary mouse models of nonalcoholic steatohepatitis B Laffitte, E Hernandez, Y Kim, B Liu, P Rucker, D Chianelli, D Bao, J Zoll, ... Journal of Hepatology 68, S341-S342, 2018	5	2018
G protein-coupled receptor GPR68 inhibits lymphocyte infiltration and contributes to gender-dependent melanoma growth S Ye, Y Zhu, D Zhong, X Song, J Li, F Xiao, Z Huang, W Zhang, M Wu, ... Frontiers in Oncology 13, 1202750, 2023	2	2023
Drug discovery for adult cardiomyocyte regeneration: opportunities and challenges X Zhao, D Li, Y Song, J Xu, FL Xiang Antioxidants & Redox Signaling 39 (16), 1070-1087, 2023		2023
Gpr68 Senses Blood Flow and is Essential for Vascular Physiology J Xu, J Mathur, E Vessieres, S Hammack, K Nonomura, J Favre, ... Circulation Research 123 (Suppl_1), A374-A374, 2018		2018
Chemical activation of the mechanotransduction channel Piezo1 M Bandell, J Xu, J Mathur, T Huynh, J Matzen, J Lao, D Tully, H Petrassi, ... eLife 4 (MAY), 2015		2015

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