Philip Van Damme
Philip Van Damme
Professor of Neuroscience, University of Leuven
Verified email at
Cited by
Cited by
EFNS guidelines on the clinical management of amyotrophic lateral sclerosis (MALS)–revised report of an EFNS task force
EFNS Task Force on Diagnosis and Management of Amyotrophic Lateral Sclerosis:
European journal of neurology 19 (3), 360-375, 2012
Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS
E Storkebaum, D Lambrechts, M Dewerchin, MP Moreno-Murciano, ...
Nature neuroscience 8 (1), 85-92, 2005
The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis
L Van Den Bosch, P Van Damme, E Bogaert, W Robberecht
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1762 (11-12 …, 2006
HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease
C d'Ydewalle, J Krishnan, DM Chiheb, P Van Damme, J Irobi, ...
Nature medicine 17 (8), 968-974, 2011
Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival
P Van Damme, A Van Hoecke, D Lambrechts, P Vanacker, E Bogaert, ...
The Journal of cell biology 181 (1), 37-41, 2008
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis
W Van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ...
Nature genetics 48 (9), 1043-1048, 2016
Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs
J Jiang, Q Zhu, TF Gendron, S Saberi, M McAlonis-Downes, A Seelman, ...
Neuron 90 (3), 535-550, 2016
Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
S Boeynaems, E Bogaert, D Kovacs, A Konijnenberg, E Timmerman, ...
Molecular cell 65 (6), 1044-1055. e5, 2017
EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans
A Van Hoecke, L Schoonaert, R Lemmens, M Timmers, KA Staats, ...
Nature medicine 18 (9), 1418-1422, 2012
Genome-wide analyses identify KIF5A as a novel ALS gene
A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ...
Neuron 97 (6), 1268-1283. e6, 2018
Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind …
JF Howard Jr, K Utsugisawa, M Benatar, H Murai, RJ Barohn, I Illa, ...
The Lancet Neurology 16 (12), 976-986, 2017
Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study
A Shatunov, K Mok, S Newhouse, ME Weale, B Smith, C Vance, ...
The Lancet Neurology 9 (10), 986-994, 2010
Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity
P Van Damme, E Bogaert, M Dewil, N Hersmus, D Kiraly, W Scheveneels, ...
Proceedings of the National Academy of Sciences 104 (37), 14825-14830, 2007
Treatment-related peripheral neuropathy in multiple myeloma: the challenge continues
M Delforge, J Bladé, MA Dimopoulos, T Facon, M Kropff, H Ludwig, ...
The lancet oncology 11 (11), 1086-1095, 2010
The C9ORF72 expansion mutation is a common cause of ALS+/− FTD in Europe and has a single founder
BN Smith, S Newhouse, A Shatunov, C Vance, S Topp, L Johnson, ...
European Journal of Human Genetics 21 (1), 102-108, 2013
Serum biomarker for progranulin‐associated frontotemporal lobar degeneration
K Sleegers, N Brouwers, P Van Damme, S Engelborghs, I Gijselinck, ...
Annals of Neurology: Official Journal of the American Neurological …, 2009
Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis
T Philips, A Bento-Abreu, A Nonneman, W Haeck, K Staats, V Geelen, ...
Brain 136 (2), 471-482, 2013
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility
International Multiple Sclerosis Genetics Consortium*†, ANZgene, ...
Science 365 (6460), eaav7188, 2019
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD
S Boeynaems, E Bogaert, E Michiels, I Gijselinck, A Sieben, A Jovičić, ...
Scientific reports 6 (1), 1-8, 2016
The C9orf72 repeat size correlates with onset age of disease, DNA methylation and transcriptional downregulation of the promoter
I Gijselinck, S Van Mossevelde, J van der Zee, A Sieben, S Engelborghs, ...
Molecular psychiatry 21 (8), 1112-1124, 2016
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