| Phthalimide conjugation as a strategy for in vivo target protein degradation GE Winter, DL Buckley, J Paulk, JM Roberts, A Souza, S Dhe-Paganon, ... Science 348 (6241), 1376-1381, 2015 | 1471 | 2015 |
| Human haploid cell genetics reveals roles for lipid metabolism genes in nonapoptotic cell death SJ Dixon, GE Winter, LS Musavi, ED Lee, B Snijder, M Rebsamen, ... ACS chemical biology 10 (7), 1604-1609, 2015 | 743 | 2015 |
| The dTAG system for immediate and target-specific protein degradation B Nabet, JM Roberts, DL Buckley, J Paulk, S Dastjerdi, A Yang, ... Nature chemical biology 14 (5), 431-441, 2018 | 715 | 2018 |
| Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation CM Olson, B Jiang, MA Erb, Y Liang, ZM Doctor, Z Zhang, T Zhang, ... Nature chemical biology 14 (2), 163-170, 2018 | 427 | 2018 |
| BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment GE Winter, A Mayer, DL Buckley, MA Erb, JE Roderick, S Vittori, JM Reyes, ... Molecular cell 67 (1), 5-18. e19, 2017 | 391 | 2017 |
| Suv39h-dependent H3K9me3 marks intact retrotransposons and silences LINE elements in mouse embryonic stem cells A Bulut-Karslioglu, A Inti, F Ramirez, M Barenboim, M Onishi-Seebacher, ... Molecular cell 55 (2), 277-290, 2014 | 322 | 2014 |
| Transcription control by the ENL YEATS domain in acute leukaemia MA Erb, TG Scott, BE Li, H Xie, J Paulk, HS Seo, A Souza, JM Roberts, ... Nature 543 (7644), 270-274, 2017 | 297 | 2017 |
| Rational discovery of molecular glue degraders via scalable chemical profiling C Mayor-Ruiz, S Bauer, M Brand, Z Kozicka, M Siklos, H Imrichova, ... Nature chemical biology 16 (11), 1199-1207, 2020 | 217 | 2020 |
| Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands LN Gechijian, DL Buckley, MA Lawlor, JM Reyes, J Paulk, CJ Ott, ... Nature chemical biology 14 (4), 405-412, 2018 | 213 | 2018 |
| Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML M Brand, B Jiang, S Bauer, KA Donovan, Y Liang, ES Wang, RP Nowak, ... Cell chemical biology 26 (2), 300-306. e9, 2019 | 201 | 2019 |
| Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma R Zeid, MA Lawlor, E Poon, JM Reyes, M Fulciniti, MA Lopez, TG Scott, ... Nature genetics 50 (4), 515-523, 2018 | 193 | 2018 |
| The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity GE Winter, B Radic, C Mayor-Ruiz, VA Blomen, C Trefzer, RK Kandasamy, ... Nature chemical biology 10 (9), 768-773, 2014 | 174 | 2014 |
| LZTR1 is a regulator of RAS ubiquitination and signaling JW Bigenzahn, GM Collu, F Kartnig, M Pieraks, GI Vladimer, LX Heinz, ... Science 362 (6419), 1171-1177, 2018 | 162 | 2018 |
| Translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders M Ishoey, S Chorn, N Singh, MG Jaeger, M Brand, J Paulk, S Bauer, ... ACS Chemical Biology 13 (3), 553-560, 2018 | 144 | 2018 |
| Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML GE Winter, U Rix, SM Carlson, KV Gleixner, F Grebien, M Gridling, ... Nature chemical biology 8 (11), 905-912, 2012 | 119 | 2012 |
| Acute BAF perturbation causes immediate changes in chromatin accessibility S Schick, S Grosche, KE Kohl, D Drpic, MG Jaeger, NC Marella, ... Nature genetics 53 (3), 269-278, 2021 | 112 | 2021 |
| Targetable BET proteins-and E2F1-dependent transcriptional program maintains the malignancy of glioblastoma L Xu, Y Chen, A Mayakonda, L Koh, YK Chong, DL Buckley, ... Proceedings of the National Academy of Sciences 115 (22), E5086-E5095, 2018 | 104 | 2018 |
| MELK is not necessary for the proliferation of basal-like breast cancer cells HT Huang, HS Seo, T Zhang, Y Wang, B Jiang, Q Li, DL Buckley, B Nabet, ... Elife 6, e26693, 2017 | 102 | 2017 |
| Methods to induce targeted protein degradation through bifunctional molecules J Bradner, D Buckley, G Winter US Patent 9,694,084, 2017 | 94 | 2017 |
| Selective Mediator dependence of cell-type-specifying transcription MG Jaeger, B Schwalb, SD Mackowiak, T Velychko, A Hanzl, H Imrichova, ... Nature genetics 52 (7), 719-727, 2020 | 87 | 2020 |
