The membrane of peroxisomes in Saccharomyces cerevisiae is impermeable to NAD (H) and acetyl‐CoA under in vivo conditions. CW Van Roermund, Y Elgersma, N Singh, RJ Wanders, HF Tabak The EMBO journal 14 (14), 3480-3486, 1995 | 384 | 1995 |
The chaperone protein BiP binds to a mutant prion protein and mediates its degradation by the proteasome T Jin, Y Gu, G Zanusso, MS Sy, A Kumar, M Cohen, P Gambetti, N Singh Journal of Biological Chemistry 275 (49), 38699-38704, 2000 | 209 | 2000 |
Proteasomal degradation and N-terminal protease resistance of the codon 145 mutant prion protein G Zanusso, RB Petersen, T Jin, Y Jing, R Kanoush, S Ferrari, P Gambetti, ... Journal of Biological Chemistry 274 (33), 23396-23404, 1999 | 207 | 1999 |
Brain iron homeostasis: from molecular mechanisms to clinical significance and therapeutic opportunities N Singh, S Haldar, AK Tripathi, K Horback, J Wong, D Sharma, A Beserra, ... Antioxidants & redox signaling 20 (8), 1324-1363, 2014 | 201 | 2014 |
Recurrent expression signatures of cytokines and chemokines are present and are independently prognostic in acute myelogenous leukemia and myelodysplasia SM Kornblau, D McCue, N Singh, W Chen, Z Estrov, KR Coombes Blood, The Journal of the American Society of Hematology 116 (20), 4251-4261, 2010 | 187 | 2010 |
The integration of certain products of the multivariableH-function with a general class of polynomials HM Srivastava, NP Singh Rendiconti del Circolo Matematico di Palermo 32 (2), 157-187, 1983 | 181 | 1983 |
Further comments on the measurement of carotid stenosis from angiograms. North American Symptomatic Carotid Endarterectomy Trial (NASCET) Group. M Eliasziw, RF Smith, N Singh, DW Holdsworth, AJ Fox, HJ Barnett Stroke 25 (12), 2445-2449, 1994 | 172 | 1994 |
Highly phosphorylated FOXO3A is an adverse prognostic factor in acute myeloid leukemia SM Kornblau, N Singh, YH Qiu, W Chen, N Zhang, KR Coombes Clinical Cancer Research 16 (6), 1865-1874, 2010 | 146 | 2010 |
Protease-resistant human prion protein and ferritin are cotransported across Caco-2 epithelial cells: implications for species barrier in prion uptake from the intestine RS Mishra, S Basu, Y Gu, X Luo, WQ Zou, R Mishra, R Li, SG Chen, ... Journal of Neuroscience 24 (50), 11280-11290, 2004 | 142 | 2004 |
Prion peptide 106–126 modulates the aggregation of cellular prion protein and induces the synthesis of potentially neurotoxic transmembrane PrP Y Gu, H Fujioka, RS Mishra, R Li, N Singh Journal of Biological Chemistry 277 (3), 2275-2286, 2002 | 120 | 2002 |
Binding of pro-prion to filamin A disrupts cytoskeleton and correlates with poor prognosis in pancreatic cancer C Li, S Yu, F Nakamura, S Yin, J Xu, AA Petrolla, N Singh, A Tartakoff, ... The Journal of clinical investigation 119 (9), 2725-2736, 2009 | 117 | 2009 |
Prion protein aggregation reverted by low temperature in transfected cells carrying a prion protein gene mutation N Singh, G Zanusso, SG Chen, H Fujioka, S Richardson, P Gambetti, ... Journal of Biological Chemistry 272 (45), 28461-28470, 1997 | 117 | 1997 |
Abnormal brain iron homeostasis in human and animal prion disorders A Singh, AO Isaac, X Luo, ML Mohan, ML Cohen, F Chen, Q Kong, J Bartz, ... PLoS pathogens 5 (3), e1000336, 2009 | 114 | 2009 |
Prion protein (PrP) knock-out mice show altered iron metabolism: a functional role for PrP in iron uptake and transport A Singh, Q Kong, X Luo, RB Petersen, H Meyerson, N Singh PLoS One 4 (7), e6115, 2009 | 111 | 2009 |
Identification of cryptic nuclear localization signals in the prion protein Y Gu, J Hinnerwisch, R Fredricks, S Kalepu, RS Mishra, N Singh Neurobiology of disease 12 (2), 133-149, 2003 | 94 | 2003 |
Prion protein regulates iron transport by functioning as a ferrireductase A Singh, S Haldar, K Horback, C Tom, L Zhou, H Meyerson, N Singh Journal of Alzheimer's Disease 35 (3), 541-552, 2013 | 92 | 2013 |
Aggresome formation by mutant prion proteins: the unfolding role of proteasomes in familial prion disorders RS Mishra, S Bose, Y Gu, R Li, N Singh Journal of Alzheimer's Disease 5 (1), 15-23, 2003 | 82 | 2003 |
Modulation of proteinase K-resistant prion protein in cells and infectious brain homogenate by redox iron: implications for prion replication and disease pathogenesis S Basu, ML Mohan, X Luo, B Kundu, Q Kong, N Singh Molecular Biology of the Cell 18 (9), 3302-3312, 2007 | 78 | 2007 |
Prion protein modulates cellular iron uptake: a novel function with implications for prion disease pathogenesis A Singh, ML Mohan, AO Isaac, X Luo, J Petrak, D Vyoral, N Singh PloS one 4 (2), e4468, 2009 | 77 | 2009 |
Prion protein functions as a ferrireductase partner for ZIP14 and DMT1 AK Tripathi, S Haldar, J Qian, A Beserra, S Suda, A Singh, U Hopfer, ... Free Radical Biology and Medicine 84, 322-330, 2015 | 72 | 2015 |